Results 31 to 40 of about 16,477,249 (235)

Estrogen Actions in Triple-Negative Breast Cancer

Cells, 2020
Triple-negative breast cancer (TNBC) lacks estrogen receptor (ER) α, but the expression of estrogen receptors ERβ and G protein-coupled estrogen receptor 1 (GPER-1) is able to trigger estrogen-responsivity in TNBC.
Oliver Treeck, Susanne Schüler-Toprak, Olaf Ortmann   +2 more
doaj   +1 more source

GPER (G protein-coupled estrogen receptor 1) [PDF]

, 2010
Review on GPER (G protein-coupled estrogen receptor 1), with data on DNA, on the protein encoded, and where the gene is ...
Eric R Prossnitz, Prossnitz, Eric R
core   +1 more source

Disruption of 3D MCF-12A breast cell cultures by estrogens - An in vitro model for ER-mediated changes indicative of hormonal carcinogenesis [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Stephanie Marchese, Elisabete Silva, Silva, E, Marchese, S, Marchese Stephanie, Silva Elisabete   +5 more
core   +1 more source

Bisphenol A attenuates the therapeutic effect of the selective G protein-coupled estrogen receptor agonist G-1 on allergic rhinitis inflammation in mice

Ecotoxicology and Environmental Safety, 2022
Background: Bisphenol A (BPA) is found in many plastics widely used in everyday life and affects the immune system. Previous studies found that the selective G protein coupled estrogen receptor (GPER) agonist G-1 can reduce the inflammation associated ...
Yunxiu Wang, Zhiwei Cao, He Zhao, Zhaowei Gu   +3 more
doaj   +1 more source

Similarity between class A and class B G-protein-coupled receptors exemplified through calcitonin gene-related peptide receptor modelling and mutagenesis studies [PDF]

, 2012
Modelling class B G-protein-coupled receptors (GPCRs) using class A GPCR structural templates is difficult due to lack of homology. The plant GPCR, GCR1, has homology to both class A and class B GPCRs. We have used this to generate a
Poyner, David, Reynolds, Christopher A., Hay, Debbie L., Poyner, David R, Barwell, James, Upton, Graham J.G., Poyner, David R., Reeves, Philip J., Upton, Graham J. G., Taddese, Bruck, Reeves, Philip J, Reynolds, Christopher A, Conner, Alex C., Hay, Debbie L, Conner, Alex C, Vohra, Shabana, Upton, Graham JG   +16 more
core   +1 more source

G Protein-Coupled Estrogen Receptor: A Potential Therapeutic Target in Cancer

Frontiers in Endocrinology, 2019
The G protein-coupled estrogen receptor (GPER) is a seven-transmembrane-domain receptor that mediates non-genomic estrogen related signaling. After ligand activation, GPER triggers multiple downstream pathways that exert diverse biological effects on the
Shen Xu, Shan Yu, Shan Yu, Daming Dong, Leo Tsz On Lee, Leo Tsz On Lee   +5 more
doaj   +1 more source

G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Mantle Cell Lymphoma Growth in Preclinical Models

Frontiers in Oncology, 2021
Mantle cell lymphoma (MCL) is an aggressive form of non-Hodgkin’s B-cell lymphoma with poor prognosis. Despite recent advances, resistance to therapy and relapse remain significant clinical problems.
Lixia Zhou, Lixia Zhou, Tenghua Yu, Fei Yang, Jingjing Han, Bin Zuo, Lulu Huang, Xia Bai, Xia Bai, Xia Bai, Xia Bai, Miao Jiang, Depei Wu, Depei Wu, Suning Chen, Suning Chen, Lijun Xia, Lijun Xia, Jia Ruan, Changgeng Ruan, Changgeng Ruan, Changgeng Ruan, Changgeng Ruan   +22 more
doaj   +1 more source

Function of G-Protein-Coupled Estrogen Receptor-1 in Reproductive System Tumors

Journal of Immunology Research, 2016
The G-protein-coupled estrogen receptor-1 (GPER-1), also known as GPR30, is a novel estrogen receptor mediating estrogen receptor signaling in multiple cell types.
Hongyan Qian, Jingxiu Xuan, Yuan Liu, Guixiu Shi   +3 more
doaj   +1 more source

The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells [PDF]

, 2008
The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes.
Bennett, DC, Venturi C, Palmigiano, A, Schiaffino, MV, Piccirillo, R, Altimare D., Rotondo G., Tacchetti, C, Marigo, V, Bagnato P., Coppola M., Rotondo, G, Venturi, C, Sviderskaya, EV, Palmisano I., Palmigiano A., Altimare D, Bagnato, P, Marigo V., Surace, EM, Altimare, D, Tacchetti C, Innamorati G., Venturi C., Surace E. M., Palmisano I, Rotondo G, INNAMORATI, Giulio, BALLABIO, ANDREA, Schiaffino M. V., Sviderskaya E. V., Palmigiano A, Innamorati G, SURACE, Enrico Maria, Sviderskaya EV, Piccirillo R, Bagnato P, Ballabio A., Incerti B, Piccirillo R., Tacchetti C., Schiaffino MV, Coppola, M, Incerti, B, Bennett DC, Incerti B., Palmisano, I, Coppola M, Bennett D. C., Innamorati, G, Ballabio, A, Marigo V   +51 more
core   +1 more source

GPER was associated with hypertension in post-menopausal women

Open Medicine, 2018
To explore the relationship between G protein-coupled estrogen receptor (GPER) and hypertension in post-menopausal women.
Liu Shichao, Ding Tongbin, Liu Hang, Jian Liguo   +3 more
doaj   +1 more source