Results 21 to 30 of about 16,618,960 (281)

Regulators of G protein signalling proteins in the human myometrium [PDF]

, 2009
The contractile state of the human myometrium is controlled by extracellular signals that promote relaxation or contraction. Many of these signals function through G proteincoupled receptors at the cell surface, stimulating heterotrimeric G proteins and ...
Ladds, Graham, Thornton, Steven, Zervou, Sevasti I., Vatish, Manu, Davey, John   +4 more
core   +1 more source

Editorial: Direct modulation of ion channels by G-proteins [PDF]

Frontiers in Physiology
Daniel Yakubovich, Daniel Yakubovich
doaj   +2 more sources

The role of inhibitory G proteins and regulators of G protein signalling in the in-vivo control of heart rate and predisposition to cardiac arrhythmias [PDF]

, 2012
Inhibitory heterotrimeric G-proteins and the control of heart rate.The activation of cell signalling pathways involving inhibitory heterotrimeric G-proteins acts to slow the heart rate via modulation of ion channels.
Aaisha Opel, Aaisha eOpel, Richard Ang, Richard eAng, Opel, A, Tinker, A, Andrew Tinker, Ang, R, Andrew eTinker   +8 more
core   +1 more source

Two RSV Platforms for G, F, or G+F Proteins VLPs

Viruses, 2020
Respiratory syncytial virus (RSV) causes substantial lower respiratory tract disease in children and at-risk adults. Though there are no effective anti-viral drugs for acute disease or licensed vaccines for RSV, palivizumab prophylaxis is available for ...
Binh Ha, Jie E. Yang, Xuemin Chen, Samadhan J. Jadhao, Elizabeth R. Wright, Larry J. Anderson   +5 more
doaj   +1 more source

14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins [PDF]

, 2013
Signaling through G proteins normally involves conformational switching between GTP- and GDP-bound states. Several Rho GTPases are also regulated by RhoGDI binding and sequestering in the cytosol.
Riou, P, O’Reilly, N., George, Roger, Ritu Garg, McColl, Brad, Ganka Bineva, Kjær, S., Svend Kjær, Garg, R, Bineva, G., Thompson, AJ, Reymond, N, Philippe Riou, Purkiss, Andrew, Nicola O’Reilly, Parker, Peter J, Brad McColl, Peter J. Parker, Neil Q. McDonald, Parker, Peter J.; id_orcid, Riou, P., Purkiss, A, Parker, PJ, Thompson, A.J., McColl, B, Cain, RJ, Parker, P.J., Kjær, Svend, McColl, B., Andrew Purkiss, O’Reilly, N, Kjær, S, Garg, R., Garg, Ritu, O'Reilly, Nicola, Anne J. Ridley, Cain, Robert J, Robert J. Cain, McDonald, Neil Q, Ridley, Anne J, Bineva, G, Ridley, A.J., Purkiss, Andrew G., Nicolas Reymond, George, R., Thompson, Andrew J, Reymond, N., Reymond, Nicolas, Bineva, Ganka, McDonald, NQ, Riou, Philippe, Andrew J. Thompson, Ridley, AJ, Kjaer, Svend, George, R, Cain, R.J., Roger George, McDonald, Neil Q., Thompson, Andrew J., Cain, Robert J., Ridley, Anne J.   +60 more
core   +1 more source

Control of striatal signaling by G protein regulators

Frontiers in Neuroanatomy, 2011
Signaling via heterotrimeric G proteins plays a crucial role in modulating the responses of striatal neurons that ultimately shape core behaviors mediated by the basal ganglia circuitry, such as reward valuation, habit formation and movement coordination.
Keqiang eXie, Kirill eMartemyanov
doaj   +1 more source

Accessory proteins for heterotrimeric G-proteins in the kidney

Frontiers in Physiology, 2015
Heterotrimeric G-proteins play a fundamentally important role in regulating signal transduction pathways in the kidney. Accessory proteins are being identified as direct binding partners for heterotrimeric G-protein α or βγ subunits to promote more ...
Frank ePark
doaj   +1 more source

G-Quadruplex-Binding Proteins: Promising Targets for Drug Design

Biomolecules, 2022
G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with the potential to form G4s are abundant in regulatory regions of the genome including telomeres, promoters and 5′ non-coding regions, indicating they fulfill ...
Huiling Shu, Rongxin Zhang, Ke Xiao, Jing Yang, Xiao Sun   +4 more
doaj   +1 more source

Role of heterotrimeric G proteins in platelet activation and clot formation in platelets treated with integrin αIIbβ3 inhibitor

Platelets, 2018
Mechanisms of platelet activation are triggered by thrombin, adenosine diphosphate (ADP), epinephrine, thromboxane A2, and other soluble agonists which induce signaling via heterotrimeric Gαq, Gαi, and Gα12/13 proteins.
Ivan Budnik, Boris Shenkman, Hagit Hauschner, Isaac Zilinsky, Naphtali Savion   +4 more
doaj   +1 more source

Cellular and subcellular localization of the RGS7/Gβ5/R7BP complex in the cerebellar cortex

Frontiers in Neuroanatomy, 2016
A member of regulator of G-protein signalling family, RGS7, is an essential modulator of signalling through GABAB receptors. RGS7 functions as a macromolecular complex with type 5 G protein β (Gβ5) and R7 binding protein (R7BP) to control the ...
Carolina Aguado, Cesare Orlandi, Ana Fajardo-Serrano, Mercedes Gil-Minguez, Kirill Martemyanov, Rafael Lujan   +5 more
doaj   +1 more source