Results 31 to 40 of about 16,618,960 (281)
Frontiers in Molecular Neuroscience, 2020 Opioid drugs are the gold standard for the management of pain, but their use is severely limited by dangerous and unpleasant side effects. All clinically available opioid analgesics bind to and activate the mu-opioid receptor (MOR), a heterotrimeric G ...
Nicolas B. Senese +6 more
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Computational Modeling for the Activation Cycle of G-proteins by G-protein-coupled Receptors [PDF]
Electronic Proceedings in Theoretical Computer Science, 2010 In this paper, we survey five different computational modeling methods. For comparison, we use the activation cycle of G-proteins that regulate cellular signaling events downstream of G-protein-coupled receptors (GPCRs) as a driving example.
Yifei Bao +3 more
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Effect of Regulator of G Protein Signaling Proteins on Bone
Frontiers in Endocrinology, 2022 Regulator of G protein signaling (RGS) proteins are critical negative molecules of G protein-coupled receptor (GPCR) signaling, which mediates a variety of biological processes in bone homeostasis and diseases.
Gongsheng Yuan +3 more
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Heterotrimeric G Proteins [PDF]
Türk Biyokimya Dergisi, 2007 Heterotrimeric G proteins, commonly known as G proteins are members of thelarge GTPase superfamily that are conserved from bacteria to mammals. G proteinsplay an essential role in cellular signaling by coupling many cell surface receptorsto effectors on ...
Bahire Küçükkaya,, Beki Kan
doaj
Study of signal transduction factors involved in mycoparasitic response of Trichoderma atroviride
浙江大学学报. 农业与生命科学版, 2004 Numerous Trichoderma spp. are mycoparasites and commercially applied as biological control agents against a large number of plant pathogenic fungi.
Scala V +9 more
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Watching G proteins at work [PDF]
Trends in Neurosciences, 1990 It has been known for over a century that rod photoreceptors in the living retina contract and swell in response to light. Although it is still not known whether this structural light-response is of any functional significance, it has recently been possible to correlate the underlying molecular processes with the activation and deactivation of the ...
Uhl, R., Wagner, R., Ryba, N.
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BioTech, 2021 G-quadruplexes are four-stranded nucleic acid structures occurring in the genomes of all living organisms and viruses. It is increasingly evident that these structures play important molecular roles; generally, by modulating gene expression and overall ...
Adriana Volná +5 more
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Insect Cell systems to Study the Communication of Mammalian Receptors and G proteins
, 2000 Cells contain large and often diverse complements of receptors that bind circulating hormones, paracrine factors, and neurotransmitters and, in so doing, initiate events that culminate in the regulation of cell function.
Manning, D.R., Barr, A.J., Windh, R.
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Regulation of large and small G proteins by ubiquitination [PDF]
, 2019 Many sensory and chemical signal inputs are transmitted by intracellular GTP-binding (G) proteins. G proteins make up two major subfamilies: "large" G proteins comprising three subunits and "small" G proteins, such as the proto-oncogene product RAS ...
Campbell, Sharon L, Dohlman, Henrik G
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Molecules, 2019 G-quadruplex is a special secondary structure of nucleic acids in guanine-rich sequences of genome. G-quadruplexes have been proved to be involved in the regulation of replication, DNA damage repair, and transcription and translation of oncogenes or ...
Zhi-Yin Sun +4 more
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