Results 131 to 140 of about 470,203 (387)

Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression

Nature Cell Biology, 2022
De Huang, Yan Wang, J. Thompson, Tao Yin, Peter B. Alexander, Diyuan Qin, Poorva Mudgal, Haiyang Wu, Yaosi Liang, Lianmei Tan, C. Pan, Lifeng Yuan, Ying Wan, Qi-jing Li, Xiao-Fan Wang   +14 more
semanticscholar   +1 more source

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

Advanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan, Keshav Gajendra Babu, Markus Mukenhirn, Antje Garside, Vinita Ajit Kini, Trishla Adhikari, Timon Beck, Byung Ho Lee, Kyoohyun Kim, Carsten Werner, Raimund Schlüßler, Alf Honigmann, Sebastian Aland, Anna Verena Taubenberger   +13 more
wiley   +1 more source

Effect of exogenous γ-aminobutyric acid (GABA) and nutrients on growth and quality of Glechoma longituba (Nakai) Kupr

Folia Horticulturae
Medicinal plants play a crucial role in both traditional and modern medicine. As demand continues to grow, the requirements for their yield and quality are becoming stringent.
Zhang Rui, Xie Zi-Yang, Zhao Bing-Nan, Jin Mei-Juan, Chen Xiao-Ran, Liu Jia-Ning, Wang Xin-Xin, Li Jia-Yi, Wei Yan-Hui, Si Chao   +9 more
doaj   +1 more source

Influence of Harvesting Time on Phytochemical Content of Colored Brown and Parboiled Rice

AGRIVITA Journal of Agricultural Science
Colored rice receives more attention from consumers because of its high phytochemicals and antioxidant activity beneficial to health. The aims of this investigation were to quantify the important phytochemicals and antioxidant activity in three varieties
Nattareeporn Rodnuch, Kiattisak Burum, Chorkaew Aninbon   +2 more
doaj   +1 more source

Plant‐Derived Melatonin Inhibits Bacterial Virulence via CpxA/R Two‐Component System

Advanced Science, EarlyView.
Plant‐derived melatonin is sensed by CpxAE48/T51, which inhibits the phosphorylation cascade transmission from CpxAH240 to CpxRD52, resulting in the inhibition of DNA‐binding capacity of CpxR and subsequent T3SS genes expression in Pst DC3000. ABSTRACT In defending against pathogens, plants deploy diverse secondary metabolites and signaling molecules ...
Jin‐Wei Wei, Wei Liu, Bili Cao, Dan Zhao, Chengqiang Wang, Xin Hou, Tangyuan Ning, Biao Gong   +7 more
wiley   +1 more source

Analysis of the protective effects of γ-aminobutyric acid during fluoride-induced hypothyroidism in male Kunming mice

Pharmaceutical Biology, 2019
Context: Compounds to treat hypothyroidism in the absence of cardiac side effects are urgently required. In this regard, γ-aminobutyric acid (GABA) has gained interest due to its anti-anxiolytic, antihypertensive and antioxidant properties, and reported ...
Haoyue Yang, Ronge Xing, Song Liu, Huahua Yu, Pengcheng Li   +4 more
doaj   +1 more source

Effect of Phytohormones of Kinetin and Epibrassinolide on Content and Intracellular Localization of Glucosides and Free Amino Acids in Pea Plants Cells (Pisum sativum L.)

International Journal of Secondary Metabolite, 2018
During injection of kinetin and epibrassinolide in pea seedlings (Pisum sativum L.) an increase of content of specific for this compound isosuccinimide-β-glucoside (IS-glucoside) for 15-30%, ethyl-β-glucoside for 40-80%, GABA free amino acids, glutamate ...
Antonina N. Ershova, Natalia Vinokurova   +1 more
doaj   +1 more source

Chronic-moderate ethanol exposure of L(tk-) cells expressing ? 4? 3? GABAA receptors reduces potency of allopregnanolone potentiation of GABA-evoked inward currents: Possible role of PKC [PDF]

, 2012
Aim: To investigate the effect of chronic-moderate ethanol (CME) treatment upon direct activation and allosteric modulation of GABAA receptors, and to assess the sensitivity of these parameters to PKC inhibition in control and ethanol-treated cells ...
Barrett, I.D., Kelley, Stephen P.
core  

Decreased BOLD Signal Variability in Middle‐Aged and Older Adults on the Autism Spectrum

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disorder. Preliminary evidence suggests an increased risk for early‐onset cognitive and neurological decline in ASD. While brain development in children, adolescents, and young adults with ASD diverges from neurotypical (NT) peers, it remains unclear in older adults with ASD ...
Stephanie Pedrahita, Annika Linke, Michaela Cordova, Molly Wilkinson, Janice Hau, Gioia Toro, Kalekirstos Alemu, Jiwandeep Kohli, Ralph‐Axel Müller, Ruth Carper   +9 more
wiley   +1 more source

Erratum to Dimorphic features of the different α-containing GABA-A receptor subtypes in the cortico-basal ganglia system of two distantly related mammals (hedgehog and rat) [PDF]

, 2000
Rosa Maria Facciolo, Raffaella Alò, Renata Tavolaro, Marcello Canonaco, Maria Fosca Franzoni   +4 more
openalex   +1 more source