Results 101 to 110 of about 60,324 (289)
PLoS Medicine, 2020 BackgroundDespite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes.
Elisabetta Patorno +6 more
doaj +1 more source
Managing menopausal symptoms and associated clinical issues in breast cancer survivors [PDF]
, 2017 Objective: Review evidence to guide management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence-based guidelines, and
Davis, Susan R. +5 more
core +1 more source
Movement Disorders, EarlyView.Abstract Background The first International Parkinson and Movement Disorder Society Evidence‐Based Medicine (MDS‐EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology was adopted by MDS, and new evidence exists.
Deepa Dash +12 more
wiley +1 more source
Development and Evaluation of Topical Gabapentin Formulations
Pharmaceutics, 2017 Topical delivery of gabapentin is desirable to treat peripheral neuropathic pain conditions whilst avoiding systemic side effects. To date, reports of topical gabapentin delivery in vitro have been variable and dependent on the skin model employed ...
Christopher J. Martin +3 more
doaj +1 more source
The effect of environment on post surgical overall well-being and pain sensitivity in an animal model [PDF]
, 2016 With chronic post surgical pain affecting up to one third of patients undergoing surgeries and the price of treatment being astoundingly high there has been a transition in research to investigate and identify risk factors. Through identification of risk
Reddy, Archana
core +1 more source
Calcium channel α2δ1 proteins mediate trigeminal neuropathic pain states associated with aberrant excitatory synaptogenesis. [PDF]
, 2014 To investigate a potential mechanism underlying trigeminal nerve injury-induced orofacial hypersensitivity, we used a rat model of chronic constriction injury to the infraorbital nerve (CCI-ION) to study whether CCI-ION caused calcium channel α2δ1 ...
Kim, Doo-Sik +7 more
core +1 more source
Pyridostigmine Treatment for Pediatric Axonal Guillain–Barré Syndrome
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aims Direct involvement of the neuromuscular junction (NMJ) in the inflammatory process of Guillain–Barré syndrome (GBS) has been described. Despite this, the NMJ very rarely serves as a target for direct medical intervention in GBS.
E. Zohar‐Dayan +3 more
wiley +1 more source
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley +1 more source
Journal of Pharmacological Sciences, 2009 .: We have recently shown that gabapentin generates protein kinase A (PKA)-dependent presynaptic inhibition of GABAergic synaptic transmission in locus coeruleus (LC) neurons only under neuropathic states.
Keiko Takasu +3 more
doaj +1 more source
Treatment of pediatric epilepsy
Pediatric Investigation, EarlyView.Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li +8 more
wiley +1 more source