Results 1 to 10 of about 4,713 (170)

Cholesterol's interfacial interactions with galactosylceramides [PDF]

Biochemistry, 1994
Recently, the influence of acyl structure on galactosylceramide's (GalCer) interfacial phase behavior was studied [Ali, S., Smaby, J. M., & Brown, R.E. (1993) Biochemistry 32, 11696-11703]. Here, we show that acyl structure is a key parameter controlling GalCer's ability to interact with cholesterol.
Rhoderick Brown, Howard L Brockman, H L Brockman   +2 more
exaly   +4 more sources

Antimalarial Activity of Axidjiferosides, New β-Galactosylceramides from the African Sponge Axinyssa djiferi

Marine Drugs, 2013
The marine sponge, Axinyssa djiferi, collected on mangrove tree roots in Senegal, was investigated for glycolipids. A mixture containing new glycosphingolipids, named axidjiferoside-A, -B and -C, accounted for 0.07% of sponge biomass (dry weight) and for
Philippe Loiseau, Jean-Michel Kornprobst, Christos Roussakis   +2 more
exaly   +4 more sources

The alpha and omega of galactosylceramides in T cell immune function. [PDF]

Journal of Biological Chemistry, 2015
Glycosphingolipids are a subgroup of glycolipids that contain an amino alcohol sphingoid base linked to sugars. They are found in the membranes of cells ranging from bacteria to vertebrates.
A. Birkholz, A. Howell, M. Kronenberg
semanticscholar   +5 more sources

Characterization of phospholipid profiles of egg yolks: Newly classified plasmalogens, distribution of polyunsaturated fatty acids, and the effects of dietary enrichment [PDF]

Food Chemistry: X
Egg yolk phospholipids are commercially valuable products that are beneficial to human health. Previous research on phospholipids in egg yolk mainly focuses on phosphatidyl choline (PC), phosphatidyl ethanolamine (PE), and fatty acid compositions, and ...
Le Cheng, Xinlei Yuan, Ming Zhang, Jianguo Dong, Yao Wu, Rang Wang, Yixuan Li, Lishui Chen, Bing Fang   +8 more
doaj   +2 more sources

Development of a Self-Adjuvanting Influenza Peptide-Glycolipid Conjugate Inducing CD8⁺ T-Cell Immunity. [PDF]

Chembiochem
The glycolipid‐peptide antigen complexes for self‐adjuvanting conjugates were successfully synthesized, and, with the HLA‐transgenic mice, the antigen‐specific CD8+ T cell expansion was exhibited. The results provide useful insights for the design and synthesis of vaccine conjugates using glycolipid antigen as an adjuvant.
Kikuchi S, Ogura H, Matsumaru T, Ishido S, Fujimoto Y.   +4 more
europepmc   +2 more sources

Norovirus GII.4 Virus‐like Particles Recognize Galactosylceramides in Domains of Planar Supported Lipid Bilayers

Angewandte Chemie - International Edition, 2012
A sticky situation: Domain-dependent recognition of the glycosphingolipid galactosylceramide by norovirus-like particles (see picture; red/yellow) is shown using supported lipid bilayers (purple) as model membranes.
Gustaf Rydell, Göran Larson, Marta Bally   +2 more
exaly   +2 more sources

Quantification and Localisation of New Brain Lipid Synthesis Using Deuterium Oxide and High Resolution Mass Spectrometry. [PDF]

Angew Chem Int Ed Engl
Liquid chromatography tandem mass spectrometry and mass spectrometry imaging were used in combination with deuterium oxide administration to quantify and localise newly synthesised myelin lipids in the mouse brain. This methodology, used here to show sites of myelin repair, enables the measurement of dynamic lipid synthesis in living systems and ...
Zhang C, Michael JA, Teo JD, Song H, Westerhausen MT, Mutuku SM, Ellis SR, Don AS.   +7 more
europepmc   +3 more sources

Synthetic efforts towards the synthesis of fluorinated C-glycosidic analogues of α-galactosylceramides

Comptes Rendus Chimie, 2012
Eric Leclerc, Xavier Pannecoucke
exaly   +2 more sources

Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis

Biomedicines, 2023
Horse-derived ceramide (HC), which contains galactosylceramides as its main component, significantly improves skin symptoms when applied topically to patients with atopic dermatitis. We speculated that efficacy resulted from the amelioration of epidermal
Tami Igarashi, Hiroki Yanagi, Masayuki Yagi, Masamitsu Ichihashi, Genji Imokawa   +4 more
doaj   +1 more source

Decrease in Myelin-Associated Lipids Precedes Neuronal Loss and Glial Activation in the CNS of the Sandhoff Mouse as Determined by Metabolomics

Metabolites, 2020
Sandhoff disease (SD) is a lysosomal disease caused by mutations in the gene coding for the β subunit of β-hexosaminidase, leading to deficiency in the enzymes β-hexosaminidase (HEX) A and B.
Emmanuelle Lecommandeur, Maria Begoña Cachón-González, Susannah Boddie, Ben D. McNally, Andrew W. Nicholls, Timothy M. Cox, Julian L. Griffin   +6 more
doaj   +1 more source