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Synthesis and Pharmacology of Galantamine
Chemical Reviews, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Marco-Contelles, J +4 more
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Galantamine for Alzheimer's disease
Expert Opinion on Drug Metabolism & Toxicology, 2010Alzheimer's disease (AD) is the most frequent, age-related neurodegenerative disorder and is characterized by progressive deterioration of cognition and global functioning. The relevance of the cholinergic system for memory, cognition and activities of daily life has been recognized decades ago, and research has demonstrated an early involvement and ...
David, Prvulovic +2 more
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Galantamine for Alzheimer's disease
2004Galantamine is a specific, competitive, and reversible acetylcholinesterase inhibitor.To assess the clinical effects of galantamine in patients with probable or possible Alzheimer's disease (AD), and potential moderators of effect.The trials were identified from a search of the Specialized Register of the Cochrane Dementia and Cognitive Improvement ...
C, Loy, L, Schneider
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Indicators of neuroprotection with galantamine
Brain Research Bulletin, 2005Alzheimer's disease is pathologically characterized by neurofibrillary tangles and beta-amyloid plaques. These observations form the basis for a large number of disease-modifying therapeutic approaches, which might ultimately lead to neuroprotection and enhanced survival of neurons. Recent data suggest a role for cholinergic stimulation, especially the
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Clinical Pharmacokinetics of Galantamine
Clinical Pharmacokinetics, 2003Galantamine is the most recently approved cholinergic drug for the treatment of Alzheimer's disease, the most common type of dementia. Vascular dementia and Alzheimer's disease with cerebrovascular disease are also common in older patients. Dementia affects cognition, causes losses in ability to perform activities of daily living and often results in ...
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