Results 251 to 260 of about 4,219,302 (284)

Cell-associated galectin 9 interacts with cytotoxic T cells confers resistance to tumor killing in nasopharyngeal carcinoma through autophagy activation. [PDF]

Cell Mol Immunol
Kam NW, Lau CY, Lau JYH, Dai X, Liang Y, Lai SPH, Chung MKY, Yu VZ, Qiu W, Yang M, Smith C, Khanna R, Ng KM, Dai W, Che CM, Lee VH, Kwong DLW.   +16 more
europepmc   +1 more source

Plasma galectin-9 relates to cognitive performance and inflammation among adolescents with vertically acquired HIV. [PDF]

AIDS
Moar P, Linn K, Premeaux TA, Bowler S, Sardarni UK, Gopalan BP, Shwe EE, San T, Han H, Clements D, Hlaing CS, Kyu EH, Thair C, Mar YY, Nway N, Mannarino J, Bolzenius J, Mar S, Aye AMM, Tandon R, Paul R, Ndhlovu LC.   +21 more
europepmc   +1 more source

ガレクチン9-Tim-3経路は1型糖尿病の治療ターゲットである [PDF]

, 2012
Kanzaki, Motoko
core  

Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior. [PDF]

iScience
Jansen SA, Cutilli A, de Koning C, van Hoesel M, Frederiks CL, Saiz Sierra L, Nierkens S, Mokry M, Nieuwenhuis EES, Hanash AM, Mocholi E, Coffer PJ, Lindemans CA.   +12 more
europepmc   +1 more source

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Galectin-9 as a biomarker of disease severity.

Cellular Immunology, 2021
Galectin-9 (Gal-9) is a β-galactoside binding lectin known for its immunomodulatory role in various microbial infections. Gal-9 is expressed in all organ systems and localized in the nucleus, cell surface, cytoplasm and the extracellular matrix. It mediates host-pathogen interactions and regulates cell signalling via binding to its receptors.
P. Moar, R. Tandon
semanticscholar   +3 more sources

Galectin-9 and PD-L1 antibody blockade combination therapy inhibits tumour progression in pancreatic cancer.

Immunotherapy, 2023
Background: The study aimed to evaluate the effect of a galectin-9 and PD-L1 combined blockade in pancreatic ductal adenocarcinoma (PDAC). Methods: The expression of galectin-9 and PD-L1 was analyzed in PDAC.
Enliang Li, Jian Xu, Qi Chen, Xiaozhen Zhang, Xingyuan Xu, T. Liang   +5 more
semanticscholar   +1 more source

Galectin-9 in Cancer Therapy

Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 2013
Galectin-9 is a tandem-repeat type galectin with two carbohydrate-recognition domains, and it was first identified as an eosinophil chemoattractant and activation factor. Subsequent studies revealed that galectin-9, similar to other galectins, modulates a variety of biological functions including cell aggregation and adhesion, as well as apoptosis of ...
Shintaro, Fujihara, Hirohito, Mori, Hideki, Kobara, Kazi, Rafiq, Toshiro, Niki, Mitsuomi, Hirashima, Tsutomu, Masaki   +6 more
openaire   +2 more sources

Serum level of galectin-9 as a potential biomarker for high risk of malignancy in dermatomyositis.

Rheumatology, 2023
OBJECTIVES Galectin-9, as immune checkpoint protein, plays a role in regulating autoimmunity and tumour immunity. Therefore, we explored the pathophysiological link between galectin-9 and malignancy in cancer-related DM (CRDM). METHODS Serum galectin-9
Yanting Shih, Shile Chen, Jie Huang, Yongheng Chen, Zicong Zhu, Qian Zhao, Xiaoqing Zhao, Feng Xue, J. Xiang, Xiao-song Chen, Xue-wen Zhu, M. Pan, Jun Wu, Jie Zheng, Hao Li, Hua Cao   +15 more
semanticscholar   +1 more source

Expression of Galectin-9-related immune checkpoint receptors in B-cell acute lymphoblastic leukemia

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Exhausted CD8+ T-cells over-express immune checkpoint receptors (ICRs), which interact with their ligands on malignant cells. However, some ICRs have been reported to be expressed on both T-cells and tumor cells, including V-domain ...
Armin Akbar, Hossein Asgarian-Omran, R. Valadan, M. Dindarloo, Ahmad Najafi, Amir Kahrizi, Arash Poursheikhani, Hossein Karami, Mohammad Naderi, Shayan Sabeti, Mohsen Tehrani   +10 more
semanticscholar   +1 more source

Association of Galectin-9 with Eosinophil Apoptosis

International Archives of Allergy and Immunology, 2002
<i>Background:</i> There is no information whether galectin-9 (a novel eosinophil chemoattractant) was associated with pathogenesis of eosinophilic disorders. <i>Methods: </i>We assessed the expression of galectin-9 with imunostaining and in situ hybridization both in the lesion of angiolymphoid hyperplasia with eosinophilia ...
Naoki, Saita, Eisuke, Goto, Taro, Yamamoto, Isamu, Cho, Kaori, Tsumori, Hirotsugu, Kohrogi, Keishi, Maruo, Tomomichi, Ono, Motohiro, Takeya, Yumiko, Kashio, Kazuhiro, Nakamura, Mitsuomi, Hirashima   +11 more
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