Results 101 to 110 of about 18,149 (205)
Bangladesh Journal of Pharmacology, 2014 Galectins are a family of structurally related carbohydrate-binding proteins and some galectins play a major role in initiation, progression and dissemination of different types of tumors.
Vipperla Bhavaniprasad +2 more
doaj +2 more sources
Biological ResearchGalectins are soluble glycan-binding proteins that interact with a wide range of glycoproteins and glycolipids and modulate a broad spectrum of physiological and pathological processes.
Elisa Perez-Moreno +7 more
doaj +1 more source
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
Mass Spectrometry Reviews, EarlyView.ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui +4 more
wiley +1 more source
Extracellular galectins as controllers of cytokines in hematological cancer.
Blood, 2018 Galectins and cytokines are both secreted proteins whose levels are prognosis factors for several cancers. Extracellular galectins bind to the glycans decorating glycoproteins and are overproduced in most cancers.
Mónica Gordón-Alonso +2 more
semanticscholar +1 more source
Neuroprotection, EarlyView.Schematic overview illustrating the experimental design and main findings of the study. Following photothrombotic stroke, mice were housed in either standard environment or enriched environment. Environmental enrichment attenuated lesion‐driven microglial inflammation and myelin damage while promoting an association between white matter triggering ...
Lluís Camprubí‐Ferrer +5 more
wiley +1 more source
The Role of Galectins in Tumor Progression, Treatment and Prognosis of Gynecological Cancers
Journal of Cancer, 2018 Galectins are the member of soluble proteins that bind with β-galactoside containing glycans. These proteins have been considered to be associated in various important events such as different types of cancers.
M. Chetry +6 more
semanticscholar +1 more source
Frontiers in Immunology, 2018 Toxoplasmic encephalitis (TE), an opportunistic infection, is a severe health problem in immunocompromised patients. Previous studies have revealed that C57BL/6 mice are susceptible and BALB/c mice are resistant to TE.
Jinfeng Liu +4 more
doaj +1 more source
ChemistryOpen, EarlyView.Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali +4 more
wiley +1 more source
Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management
Rheumatology &Autoimmunity, EarlyView.Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley +1 more source
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis
Cell Communication and SignalingFibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular ligands, fibroblast growth factors (FGFs), initiates an intracellular signaling.
Dominika Żukowska +7 more
doaj +1 more source