Gallotannin-rich Caesalpinia spinosa fraction decreases the primary tumor and factors associated with poor prognosis in a murine breast cancer model [PDF]
BACKGROUND: Several treatment alternatives are available for primary breast cancer, although those for metastatic disease or inflammation associated with tumor progression are ineffective. Therefore, there is a great need for new therapeutic alternatives
Alejandra Gomez +7 more
core +1 more source
Immune-system-dependent anti-tumor activity of a plant-derived polyphenol rich fraction in a melanoma mouse model. [PDF]
Recent findings suggest that part of the anti-tumor effects of several chemotherapeutic agents require an intact immune system. This is in part due to the induction of immunogenic cell death.
Barreto, A. +7 more
core +2 more sources
Fractionation and Characterization of Tannin Acyl Hydrolase from Aspergillus niger
We previously produced tannin acyl hydrolase (tannase) from Aspergillus niger isolated from cacao pod. In the present study the enzyme was subjected to fractionation by ammonium sulphate followed by dialysis process.
YUNITA ARIAN SANI ANWAR +2 more
doaj +3 more sources
Host Cell Poly(ADP-ribose) glycohydrolase Is Crucial for Trypanosoma cruzi Infection Cycle [PDF]
Trypanosoma cruzi, etiological agent of Chagas´ disease, has a complex life cycle which involves the invasion of mammalian host cells, differentiation and intracellular replication.
Alonso, Guillermo Daniel +5 more
core +3 more sources
The biological activities of roots and aerial parts of Alchemilla vulgaris L [PDF]
The phytochemical composition, in vitro antioxidant and antimicrobial activities, cytotoxicity and antigenotoxicity of fruit extracts of Opuntia dillenii were studied.
BAUER, PASCAL ANDRE' +9 more
core +2 more sources
Exome sequencing of a colorectal cancer family reveals shared mutation pattern and predisposition circuitry along tumor pathways [PDF]
The molecular basis of cancer and cancer multiple phenotypes are not yet fully understood. Next Generation Sequencing promises new insight into the role of genetic interactions in shaping the complexity of cancer.
Ahuja +76 more
core +2 more sources
Isolation and Screening of Fungal Isolates from Bambara (Vigna Subterranea) Nuts for Tannase Production [PDF]
Tannase (Tannin acyl hydrolase, EC 3.1.1.20) is an enzyme produced in the presence of tannic acid by various filamentous fungi. They are produced principally by fungi of the genus Aspergillus and Penicillium.
Adeniji, O. F. +6 more
core +3 more sources
The red sword bean (Canavalia gladiata) is an underutilized edible bean cultivated in China. It was previously found to have the highest content of antioxidant polyphenols among 42 edible beans, mainly gallic acid, and gallotannins in its red bean coat ...
Ren-You Gan +7 more
doaj +1 more source
Inhibition of cluster of differentiation 44 (CD44), a pancreatic cancer stem cell (CSC) marker, is a potential treatment for pancreatic ductal adenocarcinoma (PDAC). In this study, we evaluated the effect of 1,2,3,4,6-penta-O-galloyl-β-D-glucose (PGG), a
Eun-Young Kim +2 more
doaj +1 more source
Concentrações de fenóis totais nas folhas do cafeeiro durante desenvolvimento dos frutos [PDF]
Vegetables have a natural defense against external factors synthesizing phenolic compounds, which depends on the maturity stage and on the climate. Total phenol grades were extracted from mature and young coffee leaves and were analyzed in relation to ...
FAVARIN, José Laércio +3 more
core +3 more sources

