Results 41 to 50 of about 894,458 (308)

An integration of game-based learning in a classroom: an overview (2016 - 2021)

open access: yes, 2022
Games are increasingly becoming common in learning environments, and to match the requirements of developing a course as a game, a variety of technologies have been developed.
Ismaizam, Nur Maisarah   +10 more
core   +1 more source

Turning Eight Family Homes Into Interactive, Pervasive Playgrounds During the COVID-19 Pandemic Lockdown

open access: yesFrontiers in Computer Science, 2022
This paper presents an evaluation study of how eighth families adopted, played and experienced a movement-based game system of analog and digital technologies in their homes during a pandemic lockdown. The COVID-19 pandemic locked down many countries and
Louise Petersen Matjeka   +2 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The relationship between game genres, learning techniques and learning styles in educational computer games

open access: yes, 2008
Educational computer game has many similar characteristics like any other genres of games. However its particular aspect is designed to teach, and in which main objective involves in learning a topic.
Wong, K.W.   +10 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A compilation of energy costs of physical activities. [PDF]

open access: yes, 2005
OBJECTIVES: There were two objectives: first, to review the existing data on energy costs of specified activities in the light of the recommendations made by the Joint Food and Agriculture Organization/World Health Organization/United Nations University (
Vaz, Mario   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Platform independent game based educational reward system [PDF]

open access: yes, 2020
Reward has become an important role to increase students' motivation in traditional classroom learning. This research designed an In-game Card as Education Reward (ICER) web-based system which helps teachers give students reward while students have good ...
Chen, Cheng-Li
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Hubungan Antara Aktivitas Fisik dengan Kedisiplinan Anak Kelompok B di TK Pertiwi 1 Getas Kabupaten Nganjuk

open access: yesJurnal PG-PAUD Trunojoyo, 2017
Learning in early childhood has been done through studying and playing activities. Based on the result of pre-observations in TK Pertiwi 1 Getas found that the teachers do the learning process through fun physical activities to develop children's ...
Indri Wulan Suryani   +2 more
doaj   +1 more source

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