Results 51 to 60 of about 1,683,219 (290)
The mediating effect of gaming motivation between psychiatric symptoms and problematic online gaming: an online survey [PDF]
, 2015 Background: The rapid expansion of online video gaming as a leisure time activity has led to the appearance of problematic online gaming (POG). According to the literature, POG is associated with different psychiatric symptoms (eg, depression, anxiety ...
Demetrovics, Z +6 more
core +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
A legend of decolonial critique in play: A horror RPG in speculative worlds
Locus, 2023 How can scholars approach The Secret World Legends (2017), an obscure game rooted in colonialism, as a source of critique that inspires decolonial futures in media broadly?
Luke Hernandez
doaj
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Braided Environments: A Call to Explore Rhetoric and Materiality Through Augmentative Technologies
Metacritic Journal for Comparative Studies and Theory, 2018 This research proposes that augmented reality technologies have the capabilities of intertwining natural spaces, material spaces, and networked (or immaterial) spaces together through the author's original idea of the between, which can in turn be ...
Steven Smith
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Fun Versus Meaningful Video Game Experiences: A Qualitative Analysis of User Responses [PDF]
, 2016 Emerging research on video games has suggested that feelings of both enjoyment and meaningfulness can be elicited from gameplay. Studies have shown enjoyment and meaningfulness evaluations to be associated with discrete elements of video games (ratings ...
Bowman, Nicholas David +4 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Videogames: escapism or an effective tool for anticorruption enlightenment?
Russian Journal of Economics and Law, 2023 Objective: to analyze video games with anticorruption components and to make a conclusion of the possibility to use them in anticorruption education with various mechanics, plots and narratives.Methods: analysis and summarization of the narrative of ...
A. L. Melnikova, A. S. Mitsul
doaj +1 more source
The Impact of Coevolution and Abstention on the Emergence of Cooperation
, 2017 This paper explores the Coevolutionary Optional Prisoner's Dilemma (COPD) game, which is a simple model to coevolve game strategy and link weights of agents playing the Optional Prisoner's Dilemma game.
Cardinot, Marcos +2 more
core +1 more source