Results 61 to 70 of about 1,683,219 (290)
Poking fun at the surface: exploring touch-point overloading on the multi-touch tabletop with child users [PDF]
, 2012 In this paper a collaborative game for children is used to explore touch-point overloading on a multi-touch tabletop. Understanding the occurrence of new interactional limitations, such as the situation of touch-point overloading in a multi-touch ...
Fitton, Daniel Bowen +2 more
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
What is …?: a research ethics jeopardy" game to help community partners understand human subjects protections and their importance. [PDF]
, 2014 Although community partners in participatory research need to understand basic principles of research ethics and human subjects protections, few tools have been designed with these partners in mind.
Guerrero, Jaclyn +2 more
core +1 more source
, 2014 Reviews: GamesCoop, Theorien des Computerspiels zur Einführung, Hamburg (Junius) 2012. Stephan Günzel, Egoshooter. Das Raumbild des Computerspiels, Frankfurt / New York (Campus Verlag) 2013. Miguel Sicart, Beyond Choices. The Design of Ethical Gameplay, Cambridge, Mass. (MIT Press) 2013.
openaire +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Discourses and Semantic Tropes of the Philosophical Explication of Video Games
Problemos, 2019 The article explores one of the most remarkable and dynamic phenomena of modern technoculture – video games. It reconstructs the genesis of the philosophical discourse on video games, exposing the main difficulties arising in making the definitions ...
Dmitry Anatolyevich Belyaev +1 more
doaj +1 more source
Gen X and Digital Games: Looking back to look forward [PDF]
, 2018 Despite there being increased attention in recent years to older adults who actively play digital games, it seems that there has been comparatively minimal scholarly focus on the next generation of older adult gamers – Generation X gamers.
Brown, Julie A., Marston, Hannah R.
core +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source