Results 11 to 20 of about 722 (112)
What Can Gamma Delta T Cells Contribute to an HIV Cure?
Frontiers in Cellular and Infection Microbiology, 2020 Elimination of the latent HIV reservoir remains a major barrier to achieving an HIV cure. In this review, we discuss the cytolytic nature of human gamma delta T cells and highlight the emerging evidence that they can target and eliminate HIV-infected T ...
Jennifer A. Juno +3 more
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Structural analysis of TRG1@ and TRG2@ loci of the ovine immune system
Italian Journal of Animal Science, 2011 The cellular immune system visualizes the world of pathogens largely through its T cell immune receptors (TCRs), a dimer which may be αβ or γδ.
S. Ciccarese +5 more
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The influence of zoledronate and teriparatide on gamma delta T cells in mice
Journal of Dental Sciences, 2017 Background/purpose: Few studies have investigated the possibility that bisphosphonate-related osteonecrosis of the jaw (BRONJ) might reflect an immune response; however, gamma delta T cells have been shown to significantly decline in the blood of BRONJ ...
Eiki Yamachika +9 more
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Contemplating Dichotomous Nature of Gamma Delta T Cells for Immunotherapy
Frontiers in Immunology, 2022 γδ T cells are unconventional T cells, distinguished from αβ T cells in a number of functional properties. Being small in number compared to αβ T cells, γδ T cells have surprised us with their pleiotropic roles in various diseases.
Jaydeep Bhat +2 more
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Gamma-delta T cells in glioblastoma immunotherapy
Glioma, 2019 Conventional immunotherapy in the treatment of glioblastoma (GBM) has essentially produced no significant advantage over the use of chemotherapeutic drugs.
Sadhak Sengupta
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Gamma Delta T Cells and Their Pathogenic Role in Psoriasis
Frontiers in Immunology, 2021 γδT cells are an unconventional population of T lymphocytes that play an indispensable role in host defense, immune surveillance, and homeostasis of the immune system. They display unique developmental, distributional, and functional patterns and rapidly
Cong Qi +7 more
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Human peripheral CD4+ Vdelta1+ gamma delta T cells can develop into alpha beta T cells
Frontiers in Immunology, 2014 The lifelong generation of alpha beta T cells enables us to continuously build immunity against pathogens and malignancies despite the loss of thymic function with age. Consequently, alpha beta T-cell development has to occur independently of the thymus.
Hendrik eZiegler +6 more
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γδ T cells in HIV Disease: Past, Present and Future
Frontiers in Immunology, 2015 Human immunodeficiency virus type 1 (HIV) dysregulates γδ T cells as part of an immune evasion mechanism. Nearly 3 decades of research defined the effects of HIV on γδ T cells and how this impacts disease.
C. David ePauza +4 more
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Gamma Delta T Cells (γδ T Cells) in Health and Disease: In Memory of Professor Wendy Havran
Cells, 2020 Gamma delta (γδ) T cells are a small subset of CD3-positive T cells in the peripheral blood but occur at increased frequency in mucosal tissues [...]
Dieter Kabelitz
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Sheep TRD@ locus consists of a large number of TRDV elements
Italian Journal of Animal Science, 2011 The T cell receptor (TcR) expressed on mature T lymphocytes is a disulphidelinked heterodimer composed of alpha and beta or gamma and delta glycoprotein subunits.
S. Ciccarese +6 more
doaj +1 more source