Results 21 to 30 of about 722 (112)
Case Reports in Gastroenterology, 2007 Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow.
H.A. Lopez Morra +2 more
doaj +1 more source
Special Issue “Gamma Delta T Cells in Immune Response against Viruses”
Viruses, 2022 γδ T cells are members of ‘unconventional’ T cells that combine the properties of adaptive T lymphocytes and innate cells such as NK cells [...]
Eric Champagne
doaj +1 more source
Nature Communications, 2021 Gamma delta (γδ) T cells have potential for use in immunotherapy against tumours. Here, the authors demonstrate that treatment of tumours with DNA methyltransferase inhibitors modulates cytoskeleton arrangements, upregulates adhesion molecules and ...
Rueyhung R. Weng +19 more
doaj +1 more source
Gamma Delta T Cells and Their Involvement in COVID-19 Virus Infections
Frontiers in Immunology, 2021 The global outbreak of the SARS-Cov-2 virus in 2020 has killed millions of people worldwide and forced large parts of the world into lockdowns. While multiple vaccine programs are starting to immunize the global population, there is no direct cure for ...
Georg von Massow +3 more
doaj +1 more source
Multiple receptor-ligand interactions direct tissue resident gamma delta T cell activation
Frontiers in Immunology, 2014 Gamma delta T cells represent a major T cell population in epithelial tissues, such as skin, intestine, and lung, where they function in maintenance of the epithelium and provide a crucial first line defense against environmental and pathogenic insults.
Deborah A. Witherden +2 more
doaj +1 more source
The making of multivalent gamma delta TCR anti-CD3 bispecific T cell engagers
Frontiers in Immunology, 2023 IntroductionWe have recently developed a novel T cell engager concept by utilizing γ9δ2TCR as tumor targeting domain, named gamma delta TCR anti-CD3 bispecific molecule (GAB), targeting the phosphoantigen-dependent orchestration of BTN2A1 and BTN3A1 at ...
Eline van Diest +7 more
doaj +1 more source
Gamma delta (γδ) T cells: origin, phenotype, functions
Медицинская иммунологияThe primary function of γδT cells is to regulate the responses of innate and adaptive immune systems. These cells also play a role in antibacterial, antiviral and antitumor immune responses, regulate inflammation, maintain homeostasis in barrier tissues,
D. I. Sokolov
doaj +1 more source
Journal of Advanced Research, 2020 The details of the immunological microenvironment and its clinical implications for pancreatic cancer are still unclear. In this study, we obtained data from public databases, such as the Gene Expression Omnibus, the Cancer Genome Atlas Program, the ...
Caiming Xu +10 more
doaj +1 more source
Human gamma delta T regulatory cells in cancer: fact or fiction?
Frontiers in Immunology, 2014 While gamma delta T cell (γδTc) anticancer immunotherapies are being developed, recent reports suggest a regulatory role for γδTc tumor infiltrating lymphocytes (TIL).
Daniela eWesch +2 more
doaj +1 more source
Potential of gamma/delta T cells for solid tumor immunotherapy
Frontiers in ImmunologyGamma/delta T (γδ T)cells possess a unique mechanism for killing tumors, making them highly promising and distinguished among various cell therapies for tumor treatment.
Dantong Zhu +9 more
doaj +1 more source