Results 21 to 30 of about 10,381 (200)

A novel porcine gammaherpesvirus

open access: yesVirology, 2003
A novel porcine gammaherpesvirus was detected in the blood of domestic pigs by PCR. With degenerate-primer PCR and subsequent long-distance PCR approaches a 60-kbp genome stretch was amplified. Sequence analysis revealed the presence of the gammaherpesvirus ORFs 03 to 46 as well as a putative chemokine receptor and a v-bcl-2 gene.
Chmielewicz, Barbara   +10 more
openaire   +2 more sources

BAFF Receptor Deficiency Limits Gammaherpesvirus Infection [PDF]

open access: yesJournal of Virology, 2014
ABSTRACTLymphocyte colonization by gammaherpesviruses (γHVs) is an important target for cancer prevention. However, how it works is not clear. Epstein-Barr virus drives autonomous B cell proliferationin vitrobutin vivomay more subtly exploit the proliferative pathways provided by lymphoid germinal centers (GCs).
Frederico, Bruno   +3 more
openaire   +3 more sources

A Screening for Virus Infections in Eight Herds of Semi-domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) in Norway, 2013–2018

open access: yesFrontiers in Veterinary Science, 2021
Background: Previous serological screenings have indicated that Eurasian semi-domesticated tundra reindeer (Rangifer tarandus tarandus) in Finnmark, Northern Norway, are exposed to alphaherpesvirus, gammaherpesvirus and pestivirus. Alphaherpesvirus (i.e.,
Morten Tryland   +10 more
doaj   +1 more source

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

open access: yes, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara   +7 more
core   +2 more sources

NF-κB Inhibits Gammaherpesvirus Lytic Replication [PDF]

open access: yesJournal of Virology, 2003
ABSTRACT Nasopharyngeal carcinoma, Kaposi's sarcoma, and B-cell lymphomas are human malignancies associated with gammaherpesvirus infections. Members of this virus family are characterized by their ability to establish latent infections in lymphocytes. The latent viral genome expresses very few gene products.
Helen J, Brown   +5 more
openaire   +2 more sources

T Cell-Specific STAT1 Expression Promotes Lytic Replication and Supports the Establishment of Gammaherpesvirus Latent Reservoir in Splenic B Cells

open access: yesmBio, 2022
Gammaherpesviruses establish lifelong infections in most vertebrate species, including humans and rodents, and are associated with cancers, including B cell lymphomas.
P. A. Sylvester   +4 more
doaj   +1 more source

Increased risk for T cell autoreactivity to ß-cell antigens in the mice expressing the Avy obesity-associated gene. [PDF]

open access: yes, 2019
There has been considerable debate as to whether obesity can act as an accelerator of type 1 diabetes (T1D). We assessed this possibility using transgenic mice (MIP-TF mice) whose ß-cells express enhanced green fluorescent protein (EGFP). Infecting these
Atkinson, Mark A   +6 more
core   +2 more sources

The zebrafish xenograft platform-A novel tool for modeling KSHV-associated diseases [PDF]

open access: yes, 2019
Kaposi\u27s sarcoma associated-herpesvirus (KSHV, also known as human herpesvirus-8) is a gammaherpesvirus that establishes life-long infection in human B lymphocytes.
Berman, Jason N   +12 more
core   +2 more sources

Signaling Activities of Gammaherpesvirus Membrane Proteins [PDF]

open access: yesJournal of Virology, 2000
Members of the Herpesviridae family have large doublestranded DNA genomes and replicate in the nucleus of the host cell. Based on genomic organization and biological characteristics, herpesviruses are classified into three subfamilies: alpha, beta, and gamma (Fig. 1A). The gammaherpesviruses replicate and persist in lymphoid cells, but some are capable
B, Damania, J K, Choi, J U, Jung
openaire   +2 more sources

Genome sequence of a gammaherpesvirus from a common bottlenose dolphin (Tursiops truncatus) [PDF]

open access: yes, 2017
A herpesvirus genome was sequenced directly from a biopsy specimen of a rectal lesion from a female common bottlenose dolphin. This genome sequence comprises a unique region (161,235 bp) flanked by multiple copies of a terminal repeat (4,431 bp) and ...
Davison, Andrew J.   +7 more
core   +1 more source

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