Results 1 to 10 of about 4,786 (145)

Encephalomyelitis responsive to ganciclovir Encefalomielite com resposta terapêutica ao ganciclovir [PDF]

Arquivos de Neuro-Psiquiatria, 2010
Department of Neurology and Institute of Radiology, Medical School, University of Sao Paulo, Sao Paulo SP, Brazil. A 19-year-old previously healthy boy was admitted with a ten-day history of rapidly progressive urinary retention, constipation, ascending hypoesthesia up to the thoracic level and gait instability.
Anderson R.B Paiva, Samira L Apóstolos-Pereira, Leandro T Lucato, Luís R Machado, Paulo E Marchiori, Milberto Scaff   +5 more
doaj   +6 more sources

Oral Ganciclovir for Patients with Cytomegalovirus Retinitis Treated with a Ganciclovir Implant [PDF]

New England Journal of Medicine, 1999
Background The intraocular ganciclovir implant is effective for local treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome (AIDS), but it does not treat or prevent other systemic manifestations of cytomegalovirus infection.
Daniel Martín, Baruch D. Kuppermann, Richard A. Wolitz, Alan G. Palestine, Hong Li, Charles A. Robinson   +5 more
openalex   +3 more sources

Treatment of Cytomegalovirus Retinitis with Ganciclovir

Ophthalmology, 1987
Eighteen immunocompromised patients with cytomegalovirus (CMV) retinitis were treated with ganciclovir, an investigational antiviral drug. CMV retinitis in association with acquired immune deficiency syndrome (AIDS) developed in 17 patients; CMV retinitis developed in one patient after cardiac transplantation. Fourteen patients responded to ganciclovir
Douglas A. Jabs, Cheryl Newman, Serge de Bustros, B. Frank Polk   +3 more
openalex   +4 more sources

Extemporaneous Preparation of 20 mg/mL Ganciclovir in Artificial Tears in Comparison with Sterile Water for Ophthalmic Administration: Formulation and Stability Study

Pharmaceutics, 2023
Ganciclovir is available as a lyophilized powder for reconstitution and is normally used to treat ophthalmic viral infections. The use of ganciclovir in artificial tears containing hydrocolloid polymers may prove beneficial to patients during drug ...
Jiraporn Leanpolchareanchai, Patamaporn Tangteerakoon, Patcharin Supapsophon, Somsiri Sukavatcharin, Pornchai Simaroj, Jiraphong Suksiriworapong   +5 more
doaj   +1 more source

Ganciclovir Pharmacokinetics and Individualized Dosing Based on Covariate in Lung Transplant Recipients

Pharmaceutics, 2022
The aim of this prospective study was to evaluate the pharmacokinetics of ganciclovir in lung transplant recipients, to explore its covariates, and to propose an individualized dosing regimen.
Eliška Dvořáčková, Martin Šíma, Jakub Petrus, Eva Klapková, Petr Hubáček, Jiří Pozniak, Jan Havlín, Robert Lischke, Ondřej Slanař   +8 more
doaj   +1 more source

Ganciclovir-resistant cytomegalovirus [PDF]

The Lancet, 2000
Christophe Legendre
openalex   +4 more sources

A preliminary study on the UL97 gene of cytomegalovirus isolated from patients suspected of ganciclovir resistance in Sri Lanka

Sri Lankan Journal of Infectious Diseases, 2023
Background: Human cytomegalovirus (HCMV) is an opportunistic virus causing infections in immunocompromised patients. The widespread use of ganciclovir to treat CMV infections has led to the development of ganciclovir resistance.
J. C. Thambyrajah, N. Fernando, V. Rathnayake, S. Handunnetti, J. Jayamaha   +4 more
doaj   +1 more source

The need for area under the curve measurements in the field of ganciclovir therapeutic drug monitoring in children: a case report

BMC Infectious Diseases, 2021
Background Ganciclovir pharmacokinetics is characterized by a high variability in drug exposure. Usually, monitoring of ganciclovir exposure is performed by measuring trough concentration.
Xavier Duval, Florian Lemaitre, Sophie Pertuisel, Jamie Probert, Virginie Gandemer, Marie-Clémence Verdier, Camille Tron   +6 more
doaj   +1 more source

Development and Validation of Valganciclovir and its Active Metabolite Ganciclovir Determination in Human Plasma by HPLC-MS/MS Method

Разработка и регистрация лекарственных средств, 2021
Introduction. Currently, physicochemical methods of quantification are actively used to determine the content of drugs in biological fluids. High-performance liquid chromatography with various detection methods is particularly widespread. One of the most
T. N. Komarov, I. E. Shohin, M. A. Tokareva, O. A. Archakova, D. S. Bogdanova, A. V. Aleshina, N. S. Bagaeva, V. V. Davydanova   +7 more
doaj   +1 more source

A desensitization protocol to ganciclovir [PDF]

Clinical and Translational Allergy, 2014
The possibility to desensitize or induce a state of unresponsiveness to a drug that previously caused a hypersensitivity reaction is crucial when no equally safe or efficacious therapeutic alternative exists. The authors report the case of a successful desensitization to ganciclovir.
Ana Cláudia Carvalho, Josefina Rodrigues Cernadas, António Sarmento, Fabrícia Carolino   +3 more
openaire   +2 more sources