Results 51 to 60 of about 5,135,710 (246)

Target specific inhibition of West Nile virus envelope glycoprotein and methyltransferase using phytocompounds: an in silico strategy leveraging molecular docking and dynamics simulation

Frontiers in Microbiology, 2023
Mosquitoes are the primary vector for West Nile virus, a flavivirus. The virus’s ability to infiltrate and establish itself in increasing numbers of nations has made it a persistent threat to public health worldwide.
Shopnil Akash, Imren Bayıl, Md. Anisur Rahman, Nobendu Mukerjee, Nobendu Mukerjee, Swastika Maitra, Md. Rezaul Islam, Sanchaita Rajkhowa, Arabinda Ghosh, Sami A. Al-Hussain, Magdi E. A. Zaki, Vikash Jaiswal, Sanjit Sah, Sanjit Sah, Joshuan J. Barboza, Ranjit Sah, Ranjit Sah, Ranjit Sah   +17 more
doaj   +1 more source

Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice. [PDF]

Biosci Rep, 2019
AbstractThe present study aimed to investigate the protective effects of ganoderic acid A (GAA) on lipopolysaccharide (LPS)-induced acute lung injury. In mouse model of LPS-induced acute lung injury, we found that GAA led to significantly lower lung wet-to-dry weight ratio and lung myeloperoxidase activity, and attenuated pathological damages.
Wan B, Li Y, Sun S, Yang Y, Lv Y, Wang L, Song M, Chen M, Wu C, Pan H, Zhang X.   +10 more
europepmc   +4 more sources

Evaluation of Ganoderma lucidum strains for the production of bioactive components and their potential use as antimicrobial agents [PDF]

, 2015
In the present study, mycelial biomass of Ganoderma lucidum strains was produced in mushroom complete media under optimized culture conditions of temperature, pH, agitation and the fruiting bodies were raised on wheat straw supplemented with 5 per cent ...
Kapoor, Shammi, Kaur, Harsimran, Khanna, P.K., Sharma, Shivani   +3 more
core   +2 more sources

A novel approach to enhancing ganoderic acid production by Ganoderma lucidum using apoptosis induction. [PDF]

PLoS ONE, 2013
Ganoderma lucidum is one of most widely used herbal medicine and functional food in Asia, and ganoderic acids (GAs) are its active ingredients. Regulation of GA biosynthesis and enhancing GA production are critical to using G.
Bang-Jau You, Miin-Huey Lee, Ni Tien, Meng-Shiou Lee, Hui-Chuan Hsieh, Lin-Hsien Tseng, Yu-Lin Chung, Hong-Zin Lee   +7 more
doaj   +1 more source

Tissue invasion and metastasis: molecular, biological and clinical perspectives [PDF]

, 2015
Cancer is a key health issue across the world, causing substantial patient morbidity and mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to distant sites, with metastatic diseases accounting for a vast ...
Amedei, A., Amin, A., Ashraf, S., Dhawan, P., et al., Fujii, H., Georgakilas, A., Gieseler, F., Honoki, K., Jiang, W., Katoh, M., Niccolai, E., Prince, M., Sanders, A., Sarkar, M., Sliva, D., Spano, D., Subbarayan, P., Thompson, S., Ungefroren, H., Zollo, M.   +20 more
core   +1 more source

Glycosylation of Ganoderic Acid F by Bacillus Glycosyltransferase

Agrochemicals, 2022
Ganoderma lucidum is a medicinal fungus and has been used for improvements of health or prevention of certain diseases in Asia for thousands of years. Despite numerous kinds of triterpenoids having been identified from G. lucidum, few natural Ganoderma triterpenoids exist in the form of glycosides (saponins).
openaire   +1 more source

The Triterpenoid High-Performance Liquid Chromatography Analytical Profiles of the Mycelia of Ganoderma lucidum (lingzhi)

Microbiology Research, 2023
(1) Background: Ganoderic acids (GAs) are specific triterpenes of Ganoderma lucidum. The HPLC fingerprint profile of GAs of the fruiting body is well known, but their mycelial fingerprinting remains unclear.
Deng-Hai Chen, Jian-Yuan Wang, Mon-Tarng Chen, Yen-Chun Liu, Kuang-Dee Chen   +4 more
doaj   +1 more source

The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes. [PDF]

, 2014
Breast cancer metastasis is one of the major reasons for the high morbidity and mortality of breast cancer patients. In spite of surgical interventions, chemotherapy, radiation therapy and targeted therapy, some patients are considering alternative ...
Jedinak, Andrej, Jiang, Jiahua, Loganathan, Jagadish, Nakshatri, Harikrishna, Sandusky, George E., Sliva, Daniel, Smith, Amanda, Thyagarajan-Sahu, Anita   +7 more
core   +3 more sources

Methyl Ganoderic Acid DM: A Selective Potent Osteoclastogenesis Inhibitor [PDF]

The Open Bioactive Compounds Journal, 2009
Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases, and osteoclast inhibitors are the most widely used treatments for these diseases. Ganoderic acid DM, the main component of Ganoderma lucidum, has been known for its medicinal effects such as anti-androgen and anti-proliferative activities.
Jie Liu, Jun Shiono, Yukiko Tsuji, Kuniyoshi Shimizu, Ryuichiro Kondo   +4 more
openaire   +1 more source

Effect of Pd-Sensitization on Poisonous Chlorine Gas Detection Ability of TiO₂: Green Synthesis and Low-Temperature Operation

Sensors, 2022
Ganoderma lucidum mushroom-mediated green synthesis of nanocrystalline titanium dioxide (TiO2) is explored via a low-temperature (≤70 °C) wet chemical method. The role of Ganoderma lucidum mushroom extract in the reaction is to release the ganoderic acid
Satish Ekar, Umesh T. Nakate, Yogesh B. Khollam, Shoyebmohamad F. Shaikh, Rajaram S. Mane, Abu ul Hassan S. Rana, Marimuthu Palaniswami   +6 more
doaj   +1 more source