Results 61 to 70 of about 5,135,710 (246)

Delivering natural products and biotherapeutics to improve drug efficacy [PDF]

, 2017
Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery ...
Al Qaraghuli, Mohammed M., Alsaadi, Manal, Alzahrani, Abdullah R., Ferro, Valerie A., Niwasabutra, Kanidta, Obeid, Mohammad A.   +5 more
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Alcohol Extracts From Ganoderma lucidum Delay the Progress of Alzheimer’s Disease by Regulating DNA Methylation in Rodents

Frontiers in Pharmacology, 2019
Age-related changes in methylation are involved in the occurrence and development of tumors, autoimmune disease, and nervous system disorders, including Alzheimer’s disease (AD), in elderly individuals; hence, modulation of these methylation changes may ...
Guoxiao Lai, Guoxiao Lai, Yinrui Guo, Diling Chen, Xiaocui Tang, Ou Shuai, Tianqiao Yong, Dongdong Wang, Chun Xiao, Gailian Zhou, Yizhen Xie, Burton B. Yang, Burton B. Yang, Qingping Wu   +13 more
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In Vitro Antitumor Effects of the Cold-Water Extracts of Mediterranean Species of Genus Pleurotus (Higher Basidiomycetes) on Human Colon Cancer Cells [PDF]

, 2014
The aim of the present study was to evaluate whether the cold-water extract of Pleurotus eryngii var. ferulae (CWE-Pef) and Pleurotus nebrodensis (CWE-Pn), two of the most prized wild and cultivated edible mushrooms can affect the tumour phenotype of ...
Alessandro, R., Cannizzaro, A., DE LEO, G., FLUGY PAPE', A., Fontana, S., Gargano, M., Saitta, A., Schillaci, O., Venturella, G.   +8 more
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Ganoderic acid targeting nuclear factor erythroid 2–related factor 2 in lung cancer

Tumor Biology, 2017
Lung cancer causes huge mortality worldwide, and targeting new pathway may provide an alternative in modulating signaling in cancer. Nuclear factor erythroid 2–related factor 2 is the major regulator of endogenous and exogenous stress by activating ...
Balraj Singh Gill, Sanjeev Kumar, Navgeet   +2 more
doaj   +1 more source

Neurite outgrowth stimulatory effects of culinary-medicinal mushrooms and their toxicity assessment using differentiating Neuro-2a and embryonic fibroblast BALB/3T3 [PDF]

, 2013
BACKGROUND: Mushrooms are not only regarded as gourmet cuisine but also as therapeutic agent to promote cognition health. However, little toxicological information is available regarding their safety.
Chia-Wei Phan, Kah-Hui Wong, Murali Naidu, Pamela David, Vikineswary Sabaratnam   +4 more
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Improved ganoderic acids production in Ganoderma lucidum by wood decaying components [PDF]

Scientific Reports, 2017
AbstractGanoderma lucidumis a legendary Traditional Chinese Medicine (TCM) over a few thousands of years and one kind of its major active components are Ganoderic acids (GAs). GAs are largely produced in the mushroom primordium and fruiting body but much less in mycelium stage. However, little is known on the underlying regulatory mechanism.
Yanru Hu, Shakeel Ahmed, Jiawei Li, Biaobiao Luo, Zengyan Gao, Qiyun Zhang, Xiaohua Li, Xuebo Hu   +7 more
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Ganoderic Acid Me Inhibits Tumor Invasion Through Down-Regulating Matrix Metalloproteinases 2/9 Gene Expression

Journal of Pharmacological Sciences, 2008
The effect of ganoderic acid Me (GA-Me), which was purified from the fermentation mycelia of the traditional Chinese medicinal mushroom Ganoderma lucidum as reported (Tang W, Gu TY, Zhong JJ. Biochem Eng J.
Nian-Hong Chen, Jian-Wen Liu, Jian-Jiang Zhong   +2 more
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Improved Production and Antitumor Properties of Triterpene Acids from Submerged Culture of Ganoderma lingzhi

Molecules, 2016
Triterpene acids (TAs) are the major bioactive constituents in the medicinal fungus Ganoderma lingzhi. However, fermentative production of TAs has not been optimized for commercial use, and whether the TAs isolated from G.
Xiao-Ling Wang, Zhong-Yang Ding, Gao-Qiang Liu, Hailong Yang, Guo-Ying Zhou   +4 more
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Postharvest Drying Techniques Regulate Secondary Metabolites and Anti-Neuroinflammatory Activities of Ganoderma lucidum

Molecules, 2021
Ganoderma lucidum extract is a potent traditional remedy for curing various ailments. Drying is the most important postharvest step during the processing of Ganoderma lucidum.
Nooruddin-bin Sadiq, Da-Hye Ryu, Jwa-Yeong Cho, A-Hyeon Lee, Dae-Geun Song, Banzragch Dorjsembe, Jin-Chul Kim, Je-Hyeong Jung, Chu-Won Nho, Muhammad Hamayun, Seung-Hoon Yang, Ho-Youn Kim   +11 more
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Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed [PDF]

, 2014
Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural ...
A Berthod, A Berthod, A Koch, A Li, A Marston, A Maurya, A Peng, A Sun, ALM Nasser, AM Martin, AS Engelberth, AS Graham, B Diallo, B Diallo, B Medhi, B Pinel, BCB dos Santos, BK Gosse, C Zhao, CR Cheng, D Agostinho, D Du, D Fisher, D Grancher, D Wang, D Wang, D Wu, D Zhao, E Mudge, F Chen, F Chen, F Chen, F Fullas, F Gutiérrez, F He, F Oka, F Qiu, F Xiang, F Yang, G Tian, G Tian, G Wang, G Yan, GD Brown, GG Rocha, H Knapp, H Wu, H Ye, H Ye, H Zhang, HB Li, HB Li, HB Li, HB Li, HT Lu, I Slacanin, IA Sutherland, IA Sutherland, IA Sutherland, Ian Garrard, IJ Garrard, IJ Garrard, IJ Garrard, IJ Ha, J Hu, J Huang, J Liang, J Liu, J Ma, J Peng, J Wang, J Wang, J Wang, J Xie, J Xie, J Xu, J Yan, JCT Silva, JH Lee, JP Fan, JT Fischedick, JT Fischedick, JT Fischedick, K Skalicka-Woźniak, KD Yoon, KD Yoon, Krystyna Skalicka-Woźniak, KY Yoo, M Gu, M Gu, M Hamzaoui, M Lechtenberg, M Liu, M Puertas Mejia, MP Gasper, N Acton, N Fischer, N Frighetto, O Shehzad, O Shehzad, O Shehzad, O Shirota, O Shirota, P Hewitson, PA Souza De, PK Ajikumar, Q Chen, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, QB Han, QB Han, QB Han, R Aman, R Graziose, R Roscher, R Tsao, RTS Frighetto, S Baldermann, S Baldermann, S He, S Liu, S Shi, S Wu, S Wu, S Yao, S Yao, SM Kim, SS Cicek, SY Shi, T Abbott, VF Rodrigues, VGP Severino, VP da Silva, W He, X Cao, X Han, X Qi, X Shi, X Xiao, X Xin, XC Li, XH Xiao, XY Huang, Y Cheng, Y Cheng, Y Geng, Y Ikai, Y Ito, Y Ito, Y Ito, Y Ito, Y Jiang, Y Lu, Y Lu, Y Ma, Y Wang, Y Wei, Y Wei, Y Wei, Y Yang, Y Yang, Y Yuan, Y Zhang, Y Zhao, YW Ha, YW Ha, YY Dang, Z Jiang   +172 more
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