Results 31 to 40 of about 701,063 (234)

Ganoderic acid a derivative induces apoptosis of cervical cancer cells by inhibiting JNK pathway. [PDF]

Chin Herb Med
Wang M, Han Q, Zhang X, Dong X, Ran J, Wei F, Luo Y, Sun X.   +7 more
europepmc   +2 more sources

Ganoderic Acid A Metabolites and Their Metabolic Kinetics [PDF]

Frontiers in Pharmacology, 2017
Ganoderic acid A (GAA), a representative active triterpenoid from Ganoderma lucidum, has been reported to exhibit antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. The present study aims (1) to identify GAA metabolites, in vivo by analyzing the bile, plasma and urine after intravenous administration to rats (20 mg ...
Cao, Fang-Rui, Feng, Li, Ye, Lin-Hu, Wang, Li-Sha, Xiao, Bing-Xin, Tao, Xue, Chang, Qi   +6 more
openaire   +2 more sources

Analysis of Functional Components of Kangding Ganoderma leucocontextum and Its Antioxidant and Hypoglycemic Activity in Virto

Shipin gongye ke-ji, 2023
The contents of polysaccharides, triterpenes, ganoderic acid A, ganoderic acid C1 and ganoderic acid F in Kangding Ganoderma leucocontextum were analyzed by pharmacopoeia and HPLC.
Boyu ZHU, Yongqing ZHU, Hang CHEN, Zhuoya XIANG, Jiajun ZHAO, Junlin DENG, Jian CHEN, Xing YANG, Chen XIA   +8 more
doaj   +1 more source

Effects of Oleic Acid Addition Methods on the Metabolic Flux Distribution of Ganoderic Acids R, S and T’s Biosynthesis

Journal of Fungi, 2022
The effects of oleic acid addition methods on the metabolic flux distribution of ganoderic acids R, S and T’s biosynthesis from Ganoderma lucidum were investigated.
Meng-Qiu Yan, Xiao-Wei Su, Yan-Fang Liu, Chuan-Hong Tang, Qing-Jiu Tang, Shuai Zhou, Yi Tan, Li-Ping Liu, Jing-Song Zhang, Jie Feng   +9 more
doaj   +1 more source

Methyl Ganoderic Acid DM: A Selective Potent Osteoclastogenesis Inhibitor [PDF]

The Open Bioactive Compounds Journal, 2009
Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases, and osteoclast inhibitors are the most widely used treatments for these diseases. Ganoderic acid DM, the main component of Ganoderma lucidum, has been known for its medicinal effects such as anti-androgen and anti-proliferative activities.
Jie Liu, Jun Shiono, Yukiko Tsuji, Kuniyoshi Shimizu, Ryuichiro Kondo   +4 more
openaire   +1 more source

Integrated Transcriptomics and Nontargeted Metabolomics Analysis Reveal Key Metabolic Pathways in Ganoderma lucidum in Response to Ethylene

Journal of Fungi, 2022
Ganoderic acid (GA) is an important secondary metabolite of Ganoderma lucidum with a diverse array of pharmacological properties. In this study, we found that exogenous ethylene increased the production of endogenous ethylene and ganoderic acid in G ...
Li Meng, Ruyue Zhou, Jialong Lin, Qingji Wang, Panmeng Wang, Wei Wang, Li Wang, Zhuang Li   +7 more
doaj   +1 more source

Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice. [PDF]

Biosci Rep, 2019
AbstractThe present study aimed to investigate the protective effects of ganoderic acid A (GAA) on lipopolysaccharide (LPS)-induced acute lung injury. In mouse model of LPS-induced acute lung injury, we found that GAA led to significantly lower lung wet-to-dry weight ratio and lung myeloperoxidase activity, and attenuated pathological damages.
Wan B, Li Y, Sun S, Yang Y, Lv Y, Wang L, Song M, Chen M, Wu C, Pan H, Zhang X.   +10 more
europepmc   +4 more sources

Novel Glycosylation by Amylosucrase to Produce Glycoside Anomers

Biology, 2022
Glycosylation occurring at either lipids, proteins, or sugars plays important roles in many biological systems. In nature, enzymatic glycosylation is the formation of a glycosidic bond between the anomeric carbon of the donor sugar and the functional ...
Jiumn-Yih Wu, Hsiou-Yu Ding, Shun-Yuan Luo, Tzi-Yuan Wang, Yu-Li Tsai, Te-Sheng Chang   +5 more
doaj   +1 more source

The Pharmacological Potential of Mushrooms [PDF]

, 2005
This review describes pharmacologically active compounds from mushrooms. Compounds and complex substances with antimicrobial, antiviral, antitumor, antiallergic, immunomodulating, anti-inflammatory, antiatherogenic, hypoglycemic, hepatoprotective and ...
Jülich, Wolf-Dieter, Lindequist, Ulrike, Niedermeyer, Timo H. J.   +2 more
core   +3 more sources

The potential of Ganoderma lucidum extracts as bioactive ingredients in topical formulations, beyond its nutritional benefits [PDF]

, 2017
Ganoderma lucidum was characterized in terms of nutritional value and chemical composition. Thereafter, ethanolic Soxhlet extracts were evaluated for antioxidant, anti-inflammatory, antityrosinase, antimicrobial and cytotoxic effects, and further ...
Alves, Maria José, Barreiro, M.F., Barros, Lillian, Calhelha, Ricardo C., Ferreira, Isabel C.F.R., González-Paramás, Ana María, Heleno, Sandrina A., Taofiq, Oludemi   +7 more
core   +1 more source