(1) Background: Ganoderic acids (GAs) are specific triterpenes of Ganoderma lucidum. The HPLC fingerprint profile of GAs of the fruiting body is well known, but their mycelial fingerprinting remains unclear.
Deng-Hai Chen +4 more
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Evaluation of Ganoderma lucidum strains for the production of bioactive components and their potential use as antimicrobial agents [PDF]
In the present study, mycelial biomass of Ganoderma lucidum strains was produced in mushroom complete media under optimized culture conditions of temperature, pH, agitation and the fruiting bodies were raised on wheat straw supplemented with 5 per cent ...
Kapoor, Shammi +3 more
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Ganoderic acid A attenuates lipopolysaccharide-induced lung injury in mice [PDF]
AbstractThe present study aimed to investigate the protective effects of ganoderic acid A (GAA) on lipopolysaccharide (LPS)-induced acute lung injury. In mouse model of LPS-induced acute lung injury, we found that GAA led to significantly lower lung wet-to-dry weight ratio and lung myeloperoxidase activity, and attenuated pathological damages.
Bing Wan +10 more
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Tissue invasion and metastasis: molecular, biological and clinical perspectives [PDF]
Cancer is a key health issue across the world, causing substantial patient morbidity and mortality. Patient prognosis is tightly linked with metastatic dissemination of the disease to distant sites, with metastatic diseases accounting for a vast ...
Amedei, A. +20 more
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Delivering natural products and biotherapeutics to improve drug efficacy [PDF]
Due to the increasing problem of drug resistance, new and improved medicines are required. Natural products and biotherapeutics offer a vast resource for new drugs; however, challenges, including the cost and time taken for traditional drug discovery ...
Al Qaraghuli, Mohammed M. +5 more
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Glycosylation of Ganoderic Acid F by Bacillus Glycosyltransferase
Ganoderma lucidum is a medicinal fungus and has been used for improvements of health or prevention of certain diseases in Asia for thousands of years. Despite numerous kinds of triterpenoids having been identified from G. lucidum, few natural Ganoderma triterpenoids exist in the form of glycosides (saponins).
openaire +1 more source
Abiotic elicitation, a well-known strategy in mushroom biotechnology, promotes increased accumulation of secondary metabolites in mycelial cultures. The study aimed the effects of methyl jasmonate (MeJA) on the production of triterpenes in submerged ...
Katarzyna Sułkowska-Ziaja +7 more
doaj +1 more source
The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties [PDF]
BACKGROUND: The sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden or Tiger milk mushroom (Polyporales, Basidiomycota) is a valuable folk medicine for indigenous peoples in Southeast Asia. Despite the increasing interest in this ethnobotanical mushroom,
Chon-Seng Tan +6 more
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Methyl Ganoderic Acid DM: A Selective Potent Osteoclastogenesis Inhibitor [PDF]
Increased osteoclastic bone resorption plays a central role in the pathogenesis of many bone diseases, and osteoclast inhibitors are the most widely used treatments for these diseases. Ganoderic acid DM, the main component of Ganoderma lucidum, has been known for its medicinal effects such as anti-androgen and anti-proliferative activities.
Jie Liu +4 more
openaire +1 more source
Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed [PDF]
Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural ...
A Berthod +172 more
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