Results 211 to 220 of about 217,542 (316)

The Role of the Gap Junction Protein Connexin in Adrenal Gland Tumorigenesis. [PDF]

open access: yesInt J Mol Sci
Mizdrak M   +5 more
europepmc   +1 more source

Modeling and analysis of voltage gating of gap junction channels at a single-channel level. [PDF]

open access: yesBiophys J, 2023
Snipas M   +4 more
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald   +18 more
wiley   +1 more source

β-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network. [PDF]

open access: yesElife, 2023
Briggs JK   +6 more
europepmc   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Effects of Renal Denervation on Gap Junction in High-Pacing-Induced Heart Failure Dogs. [PDF]

open access: yesAnatol J Cardiol
Liang X   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy