Major Loss of the 28-kD Protein of Gap Junction in Proliferating Hepatocytes [PDF]
, 1987 There is a reduction in the 28-kD gap junction protein detectable by immunofluorescence in livers of partially hepatectomized rats and in cultured hepatocytes stimulated to proliferate. By the coordinate use of antibodies directed to the hepatic junction
Dermietzel, Rolf +4 more
core +1 more source
Comparative Analysis of the Major Polypeptides from Liver Gap Junctions and Lens Fiber Junctions [PDF]
, 1982 Gap junctions from rat liver and fiber junctions from bovine lens have similar septilaminar profiles when examined by thin-section electron microscopy and differ only slightly with respect to the packing of intramembrane particles in freeze-fracture ...
Anderson, David J. +3 more
core +2 more sources
Sex- and Age-Related Changes in Connexin 43 Expression in Normal Rat Bladder [PDF]
International Neurourology Journal, 2011 Purpose Gap junctions are intercellular channels to facilitate electrical and metabolic communication between adjacent cells. Connexin 43 is the most predominant type of connexin expressed on rat detrusor muscle cells.
Sung Ho Song +5 more
doaj +1 more source
Biology, 2021 In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap junctions, which are mainly composed of Connexin (Cx) 43, displayed immediate ultrastructural ...
Anja Beckmann +4 more
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Thalamic modulation of cingulate seizure activity via the regulation of gap junctions in mice thalamocingulate slice. [PDF]
PLoS ONE, 2013 The thalamus is an important target for deep brain stimulation in the treatment of seizures. However, whether the modulatory effect of thalamic inputs on cortical seizures occurs through the modulation of gap junctions has not been previously studied ...
Wei-Pang Chang +2 more
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Immunocytochemical localization of the main intrinsic polypeptide (MIP) in ultrathin frozen sections of rat lens. [PDF]
, 1983 The in situ distribution of the 26-kdalton Main Intrinsic Polypeptide (MIP or MP 26), a putative gap junction protein in ocular lens fibers, was defined at the electron microscope level using indirect immunoferritin labeling of ultrathin frozen sections ...
Bok, D, Fitzgerald, PG, Horwitz, J
core +1 more source
Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
Biology, 2022 For the first time in animal evolution, the emergence of gap junctions allowed direct exchanges of cellular substances for communication between two cells.
Yi Zhu
doaj +1 more source
Dense gap-junction connections support dynamic Turing structures in the cortex [PDF]
, 2007 The recent report by Fukuda et al [1] provides convincing evidence for dense gap-junction connectivity between inhibitory neurons in the cat visual cortex, each neuron making 60 +/- 12 gap-junction dendritic connections with neurons in both the same and ...
DAlistair DAlistairSteyn-Ross +4 more
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Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments
Frontiers in Physiology, 2012 Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium
Ronald eWilders
doaj +1 more source
An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. [PDF]
, 2016 Gap junction channels mediate intercellular signalling that is crucial in tissue development, homeostasis and pathologic states such as cardiac arrhythmias, cancer and trauma.
Abagyan, Ruben +9 more
core +8 more sources