Results 21 to 30 of about 2,988,528 (302)
Sex- and Age-Related Changes in Connexin 43 Expression in Normal Rat Bladder [PDF]
International Neurourology Journal, 2011 Purpose Gap junctions are intercellular channels to facilitate electrical and metabolic communication between adjacent cells. Connexin 43 is the most predominant type of connexin expressed on rat detrusor muscle cells.
Sung Ho Song +5 more
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Cellular and Molecular Life Sciences, 2019 Gap junctions consist of arrays of intercellular channels that enable adjacent cells to communicate both electrically and metabolically. Gap junctions have a wide diversity of physiological functions, playing critical roles in both excitable and non ...
M. Z. Totland +3 more
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Thalamic modulation of cingulate seizure activity via the regulation of gap junctions in mice thalamocingulate slice. [PDF]
PLoS ONE, 2013 The thalamus is an important target for deep brain stimulation in the treatment of seizures. However, whether the modulatory effect of thalamic inputs on cortical seizures occurs through the modulation of gap junctions has not been previously studied ...
Wei-Pang Chang +2 more
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Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics
Biochimica et Biophysica Acta - Biomembranes, 2017 Gap junctions are specialized membrane domains containing tens to thousands of intercellular channels. These channels permit exchange of small molecules (
J. Solan, P. Lampe
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Biology, 2021 In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap junctions, which are mainly composed of Connexin (Cx) 43, displayed immediate ultrastructural ...
Anja Beckmann +4 more
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Gap junctions in C. elegans [PDF]
Frontiers in Physiology, 2014 As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary sequence homology, but do share structural and functional similarity with ...
Karina eSimonsen +3 more
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Gap junction gene and protein families: Connexins, innexins, and pannexins
Biochimica et Biophysica Acta - Biomembranes, 2017 Gap junction channels facilitate the intercellular exchange of ions and small molecules. While this process is critical to all multicellular organisms, the proteins that form gap junction channels are not conserved. Vertebrate gap junctions are formed by
E. Beyer, V. M. Berthoud
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Intracellular Trafficking Pathways of Cx43 Gap Junction Channels
Biochimica et Biophysica Acta - Biomembranes, 2017 Gap Junction (GJ) channels, including the most common Connexin 43 (Cx43), have fundamental roles in excitable tissues by facilitating rapid transmission of action potentials between adjacent cells.
I. Epifantseva, R. Shaw
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Structure and Function of a Bacterial Gap Junction Analog
bioRxiv, 2018 Multicellular lifestyle requires cell-cell connections. In multicellular cyanobacteria, septal junctions enable molecular exchange between sister cells and are required for cellular differentiation.
G. L. Weiss +4 more
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Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
Biology, 2022 For the first time in animal evolution, the emergence of gap junctions allowed direct exchanges of cellular substances for communication between two cells.
Yi Zhu
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