Results 21 to 30 of about 1,966,785 (256)

Primary cultures of chick osteocytes retain functional gap junctions between osteocytes and between osteocytes and osteoblasts [PDF]

open access: yes, 2008
The inaccessibility of osteocytes due to their embedment in the calcified bone matrix in vivo has precluded direct demonstration that osteocytes use gap junctions as a means of intercellular communication.
Sugawara, Yasuyo   +6 more
core   +1 more source

First Responders to Hyperosmotic Stress in Murine Astrocytes: Connexin 43 Gap Junctions Are Subject to an Immediate Ultrastructural Reorganization

open access: yesBiology, 2021
In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap junctions, which are mainly composed of Connexin (Cx) 43, displayed immediate ultrastructural ...
Anja Beckmann   +4 more
doaj   +1 more source

Nitric oxide enhances de novo formation of endothelial gap junctions [PDF]

open access: yes, 2003
Objective: Gap junctions (formed by connexins, Cx) are important for functional coordination of cells in the vascular wall. However, little is known about their physiological regulation in this tissue.
Gloe, Torsten   +3 more
core   +1 more source

Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology

open access: yesBiology, 2022
For the first time in animal evolution, the emergence of gap junctions allowed direct exchanges of cellular substances for communication between two cells.
Yi Zhu
doaj   +1 more source

Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments

open access: yesFrontiers in Physiology, 2012
Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium
Ronald eWilders
doaj   +1 more source

Gap-junctional coupling between neutrophils and endothelial cells [PDF]

open access: yes, 2003
Communication between leukocytes and endothelial cells is crucial for inflammatory reactions. Paracrine cross-talk and outside-in signaling (via adhesion molecules) have been characterized as communication pathways to date.
Gloe, Torsten   +3 more
core   +1 more source

Regulation of Connexin40 Gap Junctions [PDF]

open access: yes, 2007
Gap junctions provide direct electrical and biochemical communication between cardiomyocytes in the heart. Connexin40 (Cx40) is the major connexin in the atria of the heart and little is known regarding its regulation.
Sheela, Thomas Vinaya
core   +1 more source

Dynamic changes in connexin expression correlate with key events in the wound healing process. [PDF]

open access: yes, 2003
Wound healing is a complex process requiring communication for the precise co-ordination of different cell types. The role of extracellular communication through growth factors in the wound healing process has been extensively documented, but the role of
Kamaldeep Tamber   +9 more
core   +1 more source

Connexin’s Connection in Breast Cancer Growth and Progression

open access: yesInternational Journal of Cell Biology, 2016
Gap junctions are cell-to-cell junctions that are located in the basolateral surface of two adjoining cells. A gap junction channel is composed of a family of proteins called connexins.
Debarshi Banerjee
doaj   +1 more source

Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging

open access: yesCell Reports, 2019
Summary: Connexin43 (Cx43; gene name GJA1) is the most ubiquitously expressed gap junction protein, and understanding of its regulation largely falls under transcription and post-translational modification.
Michael J. Zeitz   +7 more
doaj   +1 more source

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