Results 21 to 30 of about 142,570 (302)
Biology, 2021 In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap junctions, which are mainly composed of Connexin (Cx) 43, displayed immediate ultrastructural ...
Anja Beckmann +4 more
doaj +1 more source
Gap junctions in C. elegans [PDF]
Frontiers in Physiology, 2014 As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary sequence homology, but do share structural and functional similarity with ...
Karina eSimonsen +3 more
openaire +3 more sources
Regulation of gap junction function; the role of nitric oxide. [PDF]
, 2013 Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Kovács Mária +15 more
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Nitric oxide enhances de novo formation of endothelial gap junctions [PDF]
, 2003 Objective: Gap junctions (formed by connexins, Cx) are important for functional coordination of cells in the vascular wall. However, little is known about their physiological regulation in this tissue.
Gloe, Torsten +3 more
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Gap-junctional coupling between neutrophils and endothelial cells [PDF]
, 2003 Communication between leukocytes and endothelial cells is crucial for inflammatory reactions. Paracrine cross-talk and outside-in signaling (via adhesion molecules) have been characterized as communication pathways to date.
Gloe, Torsten +3 more
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Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
Biology, 2022 For the first time in animal evolution, the emergence of gap junctions allowed direct exchanges of cellular substances for communication between two cells.
Yi Zhu
doaj +1 more source
Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments
Frontiers in Physiology, 2012 Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium
Ronald eWilders
doaj +1 more source
Dynamic changes in connexin expression correlate with key events in the wound healing process. [PDF]
, 2003 Wound healing is a complex process requiring communication for the precise co-ordination of different cell types. The role of extracellular communication through growth factors in the wound healing process has been extensively documented, but the role of
Kamaldeep Tamber +9 more
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Connexin’s Connection in Breast Cancer Growth and Progression
International Journal of Cell Biology, 2016 Gap junctions are cell-to-cell junctions that are located in the basolateral surface of two adjoining cells. A gap junction channel is composed of a family of proteins called connexins.
Debarshi Banerjee
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Cell Reports, 2019 Summary: Connexin43 (Cx43; gene name GJA1) is the most ubiquitously expressed gap junction protein, and understanding of its regulation largely falls under transcription and post-translational modification.
Michael J. Zeitz +7 more
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