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Circulation Research, 2006 See related article, pages 1216–1224 In the late 19th century microscopy and early physiological experimentation gave rise to the apparent paradox that although cardiac muscle is made up of individual cells, it behaves as a single continuous functional unit.
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Gap Junctions in Development [PDF]
American Zoologist, 1986 The concept of a multicellular organism as an assemblage of cells that work together harmoniously for the good of the whole organism is well established. Over the past 15 years, however, it has become increasingly clear that the individual cells of multicellular animals are not as self-sufficient and independent of each other as once had been believed.
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Functional implications of calcium permeability of the channel formed by pannexin 1. [PDF]
, 2006 Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap ...
Ivanov, Dmitry, V +31 more
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Gap-Junction-Dependent Labeling of Nascent Proteins in Multicellular Networks
, 2019 Intercellular communication via gap junctions is crucial for orchestrating behaviors of multicellular systems. Imaging methods and electrophysiological techniques have been widely used to identify gap junctions and map the gap-junction-connected cell ...
Xinqi Fan (735999) +8 more
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The beneficial effects of cumulus cells and oocyte-cumulus cell gap junctions depends on oocyte maturation and fertilization methods in mice [PDF]
PeerJ, 2016 Cumulus cells are a group of closely associated granulosa cells that surround and nourish oocytes. Previous studies have shown that cumulus cells contribute to oocyte maturation and fertilization through gap junction communication.
Cheng-Jie Zhou +9 more
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Gap junctions modulate interkinetic nuclear movement in retinal progenitor cells
, 2005 During early retinal development, progenitor cells must divide repeatedly to expand the progenitor pool. During G1 and G2 of the cell cycle, progenitor cell nuclei migrate back-and-forth across the proliferative zone in a process termed interkinetic ...
Lüneborg, N.L. +7 more
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The natural cardioprotective particle HDL modulates connexin43 gap junction channels [PDF]
, 2011 High-density lipoprotein (HDL) is known for its cardioprotective properties independent from its cholesterol transport activity. These properties are mediated by activation of kinases such as protein kinase C (PKC).
James, R W +17 more
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, 2008 The inaccessibility of osteocytes due to their embedment in the calcified bone matrix in vivo has precluded direct demonstration that osteocytes use gap junctions as a means of intercellular communication.
Sugawara, Yasuyo +6 more
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Gap junction channels and cardiac impulse propagation [PDF]
, 2007 The role of gap junction channels on cardiac impulse propagation is complex. This review focuses on the differential expression of connexins in the heart and the biophysical properties of gap junction channels under normal and disease conditions ...
Dupont, Emmanuel +3 more
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International Journal of Oral Science, 2021 Gap junction (GJ) has been indicated to have an intimate correlation with adhesion junction. However, the direct interaction between them partially remains elusive.
Yueyi Yang +5 more
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