Results 51 to 60 of about 393,906 (290)

Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function.

open access: yesPLoS ONE, 2014
Mutations in GJA5 encoding the gap junction protein connexin40 (Cx40) have been linked to lone atrial fibrillation. Some of these mutants result in impaired gap junction function due to either abnormal connexin localization or impaired gap junction ...
Yiguo Sun   +4 more
doaj   +1 more source

Excitation gap of a graphene channel with superconducting boundaries

open access: yes, 2006
We calculate the density of states of electron-hole excitations in a superconductor/normal-metal/superconductor (SNS) junction in graphene, in the long-junction regime that the superconducting gap is much larger than the Thouless energy.
A. F. Andreev   +9 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Expressional and functional involvement of gap junctions in aqueous humor outflow into the ocular trabecular meshwork of the anterior chamber

open access: yesMolecular Vision, 2019
Purpose: The ocular trabecular meshwork (TM) responsible for aqueous humor (AH) drainage is crucial for regulating intraocular pressure (IOP) of the eye.
Hongxia   +7 more
doaj  

Impaired astrocytic gap junction coupling and potassium buffering in a mouse model of tuberous sclerosis complex

open access: yesNeurobiology of Disease, 2009
Abnormalities in astrocytes occur in the brains of patients with Tuberous Sclerosis Complex (TSC) and may contribute to the pathogenesis of neurological dysfunction in this disease. Here, we report that knock-out mice with Tsc1 gene inactivation in glia (
Lin Xu, Ling-Hui Zeng, Michael Wong
doaj   +1 more source

Modeling the role of gap junctions between excitatory neurons in the developing visual cortex.

open access: yesPLoS Computational Biology, 2021
Recent experiments in the developing mammalian visual cortex have revealed that gap junctions couple excitatory cells and potentially influence the formation of chemical synapses.
Jennifer Crodelle, David W McLaughlin
doaj   +1 more source

Efficiency increased in new solar cell: A Concept [PDF]

open access: yes, 1974
Graded band-gap cell should be able to convert solar radiation into electrical energy more efficiently than any solar cell currently available. Thickness of band-gap region should be chosen to maximize both quantity of light absorbed in region and ...
Hutchby, J. A.
core   +1 more source

Directional tunnelling spectroscopy of a normal metal-$s+g$-wave superconductor junction

open access: yes, 2003
We calculate the normal metal-$s+g$-wave superconductor tunnelling spectrum for various junction orientations and for two forms of the superconducting gap, one which allows for point nodes and the other which allows for line nodes.
Blonder G E   +9 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Superconducting Proximity Effect in Silicene: Spin-Valley Polarized Andreev Reflection, Non-Local Transport, and Supercurrent [PDF]

open access: yes, 2013
We theoretically study the superconducting proximity effect in silicene, which features massive Dirac fermions with a tunable mass (band gap), and compute the conductance across a normal/superconductor (N/S) silicene junction, the non-local conductance ...
Linder, Jacob, Yokoyama, Takehito
core   +2 more sources

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