Results 61 to 70 of about 393,906 (290)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Relevance of Gap Junctions and Large Pore Channels in Traumatic Brain Injury

open access: yesFrontiers in Physiology, 2014
In case of traumatic brain injury (TBI), occurrence of central nervous tissue damage is frequently aligned with local modulations of neuronal and glial gap junction channel expression levels.
Nora eProchnow
doaj   +1 more source

Src Regulation of Cx43 Phosphorylation and Gap Junction Turnover

open access: yesBiomolecules, 2020
The gap junction protein Connexin43 (Cx43) is highly regulated by phosphorylation at over a dozen sites by probably at least as many kinases. This Cx43 “kinome” plays an important role in gap junction assembly and turnover.
Joell L. Solan, Paul D. Lampe
doaj   +1 more source

Connexins evolved after early chordates lost innexin diversity

open access: yeseLife, 2022
Gap junction channels are formed by two unrelated protein families. Non-chordates use the primordial innexins, while chordates use connexins that superseded the gap junction function of innexins.
Georg Welzel, Stefan Schuster
doaj   +1 more source

Emission and Absorption quantum noise measurement with an on-chip resonant circuit

open access: yes, 2010
Using a quantum detector, a superconductor-insulator-superconductor junction, we probe separately the emission and absorption noise in the quantum regime of a superconducting resonant circuit at equilibrium.
Basset, Julien   +2 more
core   +1 more source

Charge and Spin Effects in Mesoscopic Josephson Junctions [PDF]

open access: yes, 2004
We consider the charge and spin effects in low dimensional superconducting weak links. The first part of the review deals with the effects of electron-electron interaction in Superconductor/Luttinger liquid/Superconductor junctions.
Affleck I.   +44 more
core   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

7-Ketocholesterol modulates intercellular communication through gap-junction in bovine lens epithelial cells

open access: yesCell Communication and Signaling, 2004
Background Connexin43 (Cx43) is an integral membrane protein that forms intercellular channels called gap junctions. Intercellular communication in the eye lens relies on an extensive network of gap junctions essential for the maintenance of lens ...
Pereira Paulo   +2 more
doaj   +1 more source

Backward diode composed of a metallic and semiconducting nanotube

open access: yes, 2001
The conditions necessary for a nanotube junction connecting a metallic and semiconducting nanotube to rectify the current are theoretically investigated.
A. Bachtold   +32 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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