Results 91 to 100 of about 87,868 (301)

Junctional complexes and cell-cell signalling in zebrafish morphogenesis [PDF]

, 2010
Intercellular junctions are composed of tight, gap and adherens junctions and have been shown to play many roles in embryonic morphogenesis. I have been studying the role that intercellular junctions play in zebrafish development.
Barker, D.J.
core  

Gap Junctions and Cochlear Homeostasis [PDF]

, 2006
Gap junctions play a critical role in hearing and mutations in connexin genes cause a high incidence of human deafness. Pathogenesis mainly occurs in the cochlea, where gap junctions form extensive networks between non-sensory cells that can be divided ...
Ngezahayo, Anaclet, White, T.W., Zhao, H.-B., Kikuchi, T.   +3 more
core   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Functional implications of calcium permeability of the channel formed by pannexin 1. [PDF]

, 2006
Although human pannexins (PanX) are homologous to gap junction molecules, their physiological function in vertebrates remains poorly understood. Our results demonstrate that overexpression of PanX1 results in the formation of Ca(2+)-permeable gap ...
Ivanov, Dmitry, V, Panchin, YV, Vanden Abeele, F, Fabien Vanden Abeele, Panchin, Yuri V, Gordienko, D, Yuri V. Panchin, Baranova, AV, Skryma, R, Baranova, Ancha, V, Skryma, Roman, Gordienko, Dmitri, Gabriel Bidaux, Beck, Benjamin, Ivanov, DV, Prevarskaya, N, Ancha V. Baranova, Baranova, Ancha V, Natalia Prevarskaya, Benjamin Beck, Ivanov, Dmitry V, Panchin, Yuri, Ivanov, Dimitri, Prevarskaya, Natalia, Vanden Abeele, Fabien, Bidaux, G, Bidaux, Gabriel, Dmitry V. Ivanov, Beck, B, Panchin, Yuri, V, Roman Skryma, Dmitri Gordienko   +31 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Gap junctions and non-neoplastic liver disease [PDF]

, 2012
SummaryBecause of their critical role as goalkeepers of hepatic homeostasis, gap junctions are frequent targets in liver disease. This concept has been demonstrated on many occasions in the light of hepatocarcinogenesis.
Vinken, Mathieu
core   +1 more source

Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells

Frontiers in Cellular Neuroscience, 2015
The postnatal subventricular zone lining the walls of the lateral ventricles contains neural progenitor cells (NPCs) that generate new olfactory bulb interneurons.
Rocío eTalaverón, Paola eFernández, Rosalba eEscamilla, Angel M. Pastor, Esperanza R. Matarredona, Juan Carlos eSáez   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Gap junctions and neurological disorders of the central nervous system [PDF]

, 2004
Gap junctions are intercellular channels which directly connect the cytoplasm between neighboring cells. In the central nervous system (CNS) various kinds of cells are coupled by gap junctions, which play an important role in maintaining normal function.
Taizen Nakase, Naus, Christian C.G., Christian C.G. Naus, Nakase, Taizen   +3 more
core   +1 more source

Vitamin D3 regulates the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells.

PLoS ONE, 2014
1α-25(OH)2 vitamin D3 (1-25D), an active hormonal form of Vitamin D3, is a well-known chemopreventive and pro-differentiating agent. It has been shown to inhibit the growth of several prostate cancer cell lines.
Linda Kelsey, Parul Katoch, Anuttoma Ray, Shalini Mitra, Souvik Chakraborty, Ming-Fong Lin, Parmender P Mehta   +6 more
doaj   +1 more source