Results 141 to 150 of about 22,095 (292)
Gasdermin E-mediated programmed cell death: An unpaved path to tumor suppression [PDF]
, 2021 Yueyuan Wang +5 more
openalex +1 more source
Brain and Behavior, Volume 16, Issue 2, February 2026.Rhein treatment inhibits NLRP3 inflammasome activation, suppresses Caspase‐1/GSDMD‐mediated pyroptosis, reduces pro‐inflammatory cytokine release, promotes M2 polarization, and improves behavioral outcomes of ICH. These findings suggest that rhein protects against ICH‐induced brain injury through the inhibition of NLRP3‐dependent pyroptosis ...
Adalaiti Aimaiti +7 more
wiley +1 more source
Novel pyroptosis-independent functions of gasdermins
Signal Transduction and Targeted Therapy, 2022 Ziran Qin, Fangfang Zhou, Long Zhang
openaire +3 more sources
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.Irigenin alleviates blue light‐induced RPE cell damage by inhibiting NLRP3 inflammasome and p38/NF‐κB signalling, showing potential for AMD prevention. ABSTRACT Age‐related macular degeneration (AMD), a primary cause of vision loss among older adults, is strongly associated with inflammatory processes.
I‐Li Su +9 more
wiley +1 more source
Jefferson Digital Commons quarterly report: April-June 2019 [PDF]
, 2018 This quarterly report includes: Articles CREATE Day Presentations Dissertations From the Archives Grand Rounds and Lectures House Staff Quality Improvement and Patient Safety Posters JCIPE Student Hotspotting Posters Journals and Newsletters MPH ...
Copeland, LIBT, James +1 more
core +2 more sources
Ventilator‐Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.Mechanical ventilation (MV) is expected to undergo significant transformative advancements by 2050, with the emergence of personalized ventilation systems that promise to revolutionize respiratory care. However, the risk of ventilator‐induced lung injury (VILI) remains a significant concern at this stage and VILI still exists at that time.
He Ren +4 more
wiley +1 more source
Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment
Frontiers in ImmunologyBackgroundThe interaction between pyroptosis—a form of programmed cell death—and tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in cancer: it can both promote tumor development and counteract it by activating ...
Qinan Yin +9 more
doaj +1 more source
Nucleic acid sensors and programmed cell death [PDF]
, 2020 Liverpool, Layal +2 more
core +2 more sources
Molecular characterization of a fungal gasdermin-like protein [PDF]
, 2020 Asen Daskalov +4 more
openalex +1 more source
DL-3-n-Butylphthalide Attenuates Myocardial Hypertrophy by Targeting Gasdermin D and Inhibiting Gasdermin D Mediated Inflammation [PDF]
, 2021 Bingjiang Han +6 more
openalex +1 more source