Results 31 to 40 of about 1,763,342 (188)

A spinal neural circuitry for converting touch to itch sensation

open access: yesNature Communications, 2020
Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (
Sihan Chen   +11 more
doaj   +1 more source

Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP) [PDF]

open access: yes, 2009
Background: Pro-gastrin releasing peptide ( ProGRP) concentrations in blood play an important role in the diagnosis and treatment of patients with small cell lung cancer (SCLC).
Patil, Rahul D.   +17 more
core   +1 more source

Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells

open access: yesBeilstein Journal of Nanotechnology, 2019
Background: Gastrin-releasing peptide is a member of the bombesin family of peptides. Its cognate receptor, gastrin releasing peptide receptor (GRPR), is widely expressed in cancers of the lung, pancreas and ovaries. Gastrin releasing peptide (GRP) is an
Mohammad J. Akbar   +4 more
doaj   +1 more source

Gastrin releasing peptide receptor mediates its morphogenic properties via ICAM-1 and Hsp72.

open access: yes, 2009
Gastrin releasing peptide receptor mediates its morphogenic properties via ICAM-1 and ...
Lauren Nicole. Taglia (7988618)
core   +6 more sources

Gastrin-releasing peptide receptors in the central nervous system: role in brain function and as a drug target

open access: yesFrontiers in Endocrinology, 2012
Neuropeptides acting on specific cell membrane receptors of the G protein-coupled receptor (GPCR) superfamily regulate a range of important aspects of nervous and neuroendocrine function.
Rafael eRoesler, Gilberto eSchwartsmann
doaj   +1 more source

New Frontiers in Molecular Imaging Using Peptide-Based Radiopharmaceuticals for Prostate Cancer

open access: yesFrontiers in Chemistry, 2020
The high incidence of prostate cancer (PCa) increases the need for progress in its diagnosis, staging, and precise treatment. The overexpression of tumor-specific receptors for peptides in human cancer cells, such as gastrin-releasing peptide receptor ...
Xin Li   +5 more
doaj   +1 more source

Expression of gastrin-releasing peptide receptor in human skin.

open access: yesActa Dermato-Venereologica, 1996
Bombesin-related peptides are expressed in the skin of batrachians and mammals. As gastrin-releasing peptide belongs to this family, we searched for the presence and distribution of gastrin-releasing peptide receptors (GRPr) in the skin of healthy human adults by immunohistochemistry, flow cytometry and electron microscopy.
Staniek, V.   +7 more
openaire   +3 more sources

Function of gastrin-releasing peptide receptors in ocular itch transmission in the mouse trigeminal sensory system

open access: yes, 2023
The prevalence of allergic conjunctivitis in itchy eyes has increased constantly worldwide owing to environmental pollution. Currently, anti-allergic and antihistaminic eye drops are used; however, there are many unknown aspects about the neural circuits
坂本 浩隆   +17 more
core   +1 more source

Lasting and Sex-Dependent Impact of Maternal Immune Activation on Molecular Pathways of the Amygdala

open access: yesFrontiers in Neuroscience, 2020
The prolonged and sex-dependent impact of maternal immune activation (MIA) during gestation on the molecular pathways of the amygdala, a brain region that influences social, emotional, and other behaviors, is only partially understood.
Marissa R. Keever   +16 more
doaj   +1 more source

Direct Observation of Endocytosis of Gastrin Releasing Peptide and Its Receptor [PDF]

open access: yesJournal of Biological Chemistry, 1995
Endocytosis of the gastrin releasing peptide receptor (GRP-R) may regulate cellular responses to GRP. We observed endocytosis in transfected epithelial cells by confocal microscopy using cyanine 3-GRP (cyanine 3.18-labeled gastrin releasing peptide) and GRP-R antibodies. At 4 degrees C, cy3-GRP and GRP-R were confined to the plasma membrane.
E F, Grady   +5 more
openaire   +2 more sources

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