Results 71 to 80 of about 158,364 (287)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

The Origin and Understanding of the Incretin Concept

open access: yesFrontiers in Endocrinology, 2018
Gastrointestinal hormones that stimulate insulin secretion at physiological concentrations are incretins. This concept has recently attracted considerable attention in the wake of drugs developed from the gut hormone GLP-1 (glucagon-like peptide-1) for ...
Jens F. Rehfeld
doaj   +1 more source

The Potential Role of Gut Peptide Hormones in Autism Spectrum Disorder

open access: yesFrontiers in Cellular Neuroscience, 2020
Gut peptide hormones are one group of secretory factors produced from gastrointestinal endocrine cells with potent functions in modulating digestive functions.
Xin-Rui Qi, Li Zhang
doaj   +1 more source

Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]

open access: yes, 2017
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core   +2 more sources

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

open access: yesAdvanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li   +7 more
wiley   +1 more source

Effect of Da Vinci Robot Radical Gastrectomy on Gastrointestinal Motility and Gastrointestinal Hormones of Gastric Cancer Patients

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To investigate the effect of Da Vinci robot radical gastrectomy on gastrointestinal motility and hormones of gastric cancer patients. Methods We selected 217 patients who underwent radical gastrectomy.
HAN Boqiang   +5 more
doaj   +1 more source

Intestinal transplantation in composite visceral grafts or alone [PDF]

open access: yes, 1992
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match).
Abu-Elmagd, K   +17 more
core   +1 more source

Atrophic Skeletal Muscle‐Derived Extracellular Vesicles Transfer miR‐125a‐5p to Inhibit Bone Formation in Osteoporosis during Aging

open access: yesAdvanced Science, EarlyView.
A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao   +22 more
wiley   +1 more source

Role of Fibre in Nutritional Management of Pancreatic Diseases [PDF]

open access: yes, 2019
The role of fibre intake in the management of patients with pancreatic disease is still controversial. In acute pancreatitis, a prebiotic enriched diet is associated with low rates of pancreatic necrosis infection, hospital stay, systemic inflammatory ...
Badiali, Danilo   +7 more
core   +1 more source

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