Results 51 to 60 of about 7,571 (179)

JNK Mediates Differentiation, Cell Polarity and Apoptosis During Amphioxus Development by Regulating Actin Cytoskeleton Dynamics and ERK Signalling

Frontiers in Cell and Developmental Biology, 2021
c-Jun N-terminal kinase (JNK) is a multi-functional protein involved in a diverse array of context-dependent processes, including apoptosis, cell cycle regulation, adhesion, and differentiation.
Ildiko M. L. Somorjai, Ildiko M. L. Somorjai, Ildiko M. L. Somorjai, Matthias T. Ehebauer, Hector Escrivà, Jordi Garcia-Fernàndez, Jordi Garcia-Fernàndez   +6 more
doaj   +1 more source

Depleted Dissolved Oxygen Concentrations Impair the Embryonic and Early Larval Development of Eastern Hellbenders (Cryptobranchus alleganiensis)

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 2, Page 112-126, March 2026.
ABSTRACT Depletion of dissolved oxygen (DO; hypoxia) and its influence on sensitive fauna and vulnerable life stages is an emerging concern in lotic freshwater ecosystems. A species particularly vulnerable to hypoxia is the Eastern Hellbender—a large‐bodied, fully aquatic salamander which relies on cutaneous respiration and has evolved to thrive in ...
Holly A. Funkhouser, Austin Holloway, Katherine L. Slack, William A. Hopkins   +3 more
wiley   +1 more source

Conjoined Parasitic Twins (Cephalo‐Thoracopagus Parasiticus) in a Free Ranging Northern Bat (Eptesicus nilssonii): A Micro‐CT Anatomic and Genetic Survey

Anatomia, Histologia, Embryologia, Volume 55, Issue 2, March 2026.
ABSTRACT The detailed anatomical situation of male stillborn cephalo‐thoracopagus twins in a wild ranging northern bat (Eptesicus nilssonii) is described by means of full body micro‐CT scans in high resolution with three‐dimensional computational reconstruction.
J. Meyer, V. N. Laine, J. van der Kooij, B. Richter, S. Handschuh, M. Gumpenberger   +5 more
wiley   +1 more source

Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock‐ins

Developmental Dynamics, Volume 255, Issue 1, Page 86-105, January 2026.
Abstract Background The ability to generate endogenous Cre recombinase drivers using CRISPR‐Cas9 knock‐in technology allows lineage tracing, cell type‐specific gene studies, and in vivo validation of inferred developmental trajectories from phenotypic and gene expression analyses. This report describes endogenous zebrafish hand2 Cre and CreERT2 drivers
Zhitao Ming, Fang Liu, Hannah R. Moran, Robert L. Lalonde, Megan Adams, Nicole K. Restrepo, Parnal Joshi, Stephen C. Ekker, Karl J. Clark, Iddo Friedberg, Saulius Sumanas, Chunyue Yin, Christian Mosimann, Jeffrey J. Essner, Maura McGrail   +14 more
wiley   +1 more source

Cell contacts and pericellular matrix in the Xenopus gastrula chordamesoderm.

PLoS ONE
Convergent extension of the chordamesoderm is the best-examined gastrulation movement in Xenopus. Here we study general features of cell-cell contacts in this tissue by combining depletion of adhesion factors C-cadherin, Syndecan-4, fibronectin, and ...
Olivia Luu, Debanjan Barua, Rudolf Winklbauer   +2 more
doaj   +3 more sources

RESPIRATORY METABOLISM OF AMPHIBIAN GASTRULA EXPLANTS

The Biological Bulletin, 1952
1. In full-strength Holtfreter's solution, dorsal explants from Rana pipiens gastrulae respire some 20% faster than ventral explants from the same gastrulae (with respect to dry weight). Lateral halves of dorsal explants respire at the same rate; and lateral halves of ventral explants respire at the same rate.2.
NORMA ORNSTEIN, JOHN R. GREGG
openaire   +2 more sources

Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula

eLife, 2017
During amphibian gastrulation, presumptive endoderm is internalised as part of vegetal rotation, a large-scale movement that encompasses the whole vegetal half of the embryo. It has been considered a gastrulation process unique to amphibians, but we show
Jason WH Wen, Rudolf Winklbauer
doaj   +1 more source

The Zinc Finger Protein Znf281 Is Essential for the Formation of Neural Tissue in Xenopus Embryos

Development, Growth &Differentiation, Volume 68, Issue 1, January 2026.
ABSTRACT Zinc finger protein 281 (Znf281) plays important roles in human malignancies, stem cell pluripotency, and placental and embryonic development. However, the function of Znf281 during early neural development remains unclear. Here, we investigated the role of Znf281 in the formation of neural tissue in Xenopus embryos.
Ryota Koike, Makoto Nakamura, Kimiko Takebayashi‐Suzuki, Atsushi Suzuki   +3 more
wiley   +1 more source

Cell Fate Determination and Lineage Tracing: Technological Evolution and Multidimensional Applications

Advanced Science, Volume 12, Issue 41, November 6, 2025.
This figure is a candidate for the cover image. It shows a whole‐mount fluorescent image of lymphatic vessels (red) in the heart of an adult Cdh5‐Dre; Prox1‐RSR‐CreER; Rosa26‐tdT mouse. Image courtesy of Ximeng Han. Abstract Cell fate determination is a fundamental process in multicellular development.
Hui Chen, Zhicong Liu, Qiang Shu, Bin Zhou   +3 more
wiley   +1 more source

Mesomere-derived glutamate decarboxylase-expressing blastocoelar mesenchyme cells of sea urchin larvae

Biology Open, 2013
Summary The ontogenetic origin of blastocoelar glutamate decarboxylase (GAD)-expressing cells (GADCs) in larvae of the sea urchin Hemicentrotus pulcherrimus was elucidated.
Hideki Katow, Tomoko Katow, Kouki Abe, Shioh Ooka, Masato Kiyomoto, Gen Hamanaka   +5 more
doaj   +1 more source