Results 1 to 10 of about 10,115 (192)
The evolution of gastrulation morphologies
Development, 2023 During gastrulation, early embryos specify and reorganise the topology of their germ layers. Surprisingly, this fundamental and early process does not appear to be rigidly constrained by evolutionary pressures; instead, the morphology of gastrulation is ...
Guillermo Serrano Nájera +1 more
semanticscholar +4 more sources
Multi-omics profiling of mouse gastrulation at single-cell resolution
Nature, 2019 Formation of the three primary germ layers during gastrulation is an essential step in the establishment of the vertebrate body plan and is associated with major transcriptional changes1–5.
Berthold Göttgens +2 more
exaly +2 more sources
Attachment of the blastoderm to the vitelline envelope affects gastrulation of insects
Nature, 2019 During gastrulation, physical forces reshape the simple embryonic tissue to form the complex body plans of multicellular organisms1. These forces often cause large-scale asymmetric movements of the embryonic tissue2,3.
Akanksha Jain +2 more
exaly +2 more sources
Folded gastrulation and T48 drive the evolution of coordinated mesoderm internalization in flies
eLife, 2016 Gastrulation constitutes a fundamental yet diverse morphogenetic process of metazoan development. Modes of gastrulation range from stochastic translocation of individual cells to coordinated infolding of an epithelial sheet.
Silvia Urbansky +3 more
doaj +2 more sources
PLoS Biology, 2019 In vitro models of postimplantation human development are valuable to the fields of regenerative medicine and developmental biology. Here, we report characterization of a robust in vitro platform that enabled high-content screening of multiple human ...
Mukul Tewary +16 more
doaj +2 more sources
A single-embryo, single-cell time-resolved model for mouse gastrulation
Cell, 2021 Saifeng Cheng +2 more
exaly +2 more sources
A single-cell molecular map of mouse gastrulation and early organogenesis
Nature, 2019 Blanca Pijuan-sala +2 more
exaly +2 more sources
Embryo model completes gastrulation to neurulation and organogenesis
Nature, 2022 Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro1–5, but their developmental potential is substantially extended by interactions with extraembryonic stem cells, including trophoblast stem (TS) cells, extraembryonic ...
G. Amadei +14 more
semanticscholar +1 more source
Biology Open, 2022 Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis.
Tingxu Chen +6 more
doaj +1 more source
eLife, 2022 Screening for drugs that disrupt embryonic development in zebrafish can help identify treatments that suppress metastasis.
Chinyere Kemet, Emily Hill, Hui Feng
doaj +1 more source