Results 1 to 10 of about 50,111 (168)
Extracellular presentation of syntaxin4 as a potential trigger for region-specific gastrulation [PDF]
Cell Structure and FunctionDuring early embryogenesis, gastrulation occurs within a specific region of the pluripotent epiblast, where cells undergo significant changes in their context.
Sae Nozaki, Taisei Mihara, Yohei Hirai
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Developmental Biology, 2021 During development, a single cell is transformed into a highly complex organism through progressive cell division, specification and rearrangement. An important prerequisite for the emergence of patterns within the developing organism is to establish asymmetries at various scales, ranging from individual cells to the entire embryo, eventually giving ...
Alexandra Schauer +1 more
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eLife, 2022 Screening for drugs that disrupt embryonic development in zebrafish can help identify treatments that suppress metastasis.
Chinyere Kemet, Emily Hill, Hui Feng
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Frontiers in Cell and Developmental Biology, 2023 Fetal Alcohol Spectrum Disorder (FASD) arises from maternal consumption of alcohol during pregnancy affecting 2%–5% of the Western population. In Xenopus laevis studies, we showed that alcohol exposure during early gastrulation reduces retinoic acid (RA)
B. Petrelli +5 more
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, 2020 Tunicates are a diverse group of invertebrate marine chordates that includes the larvaceans, thaliaceans, and ascidians. Because of their unique evolutionary position as the sister group of the vertebrates, tunicates are invaluable as a comparative model and hold the promise of revealing both conserved and derived features of chordate gastrulation ...
Konner M, Winkley +4 more
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Stem Cell Reports, 2023 Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul +8 more
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Biology Open, 2022 Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis.
Tingxu Chen +6 more
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eLife, 2020 Ventral furrow formation, the first step in Drosophila gastrulation, is a well-studied example of tissue morphogenesis. Rho1 is highly active in a subset of ventral cells and is required for this morphogenetic event.
Ashley Rich +2 more
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Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation
eLife, 2022 Cells sense and integrate external information from diverse sources that include mechanical cues. Shaping of tissues during development may thus require coordination between mechanical forces from morphogenesis and cell-cell signalling to confer ...
Julia Falo-Sanjuan, Sarah Bray
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Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. [PDF]
PLoS ONE, 2018 Gastrulation is the initial systematic deformation of the embryo to form germ layers, which is characterized by the placement of appropriate cells in their destined locations.
Yuta Yamamoto +8 more
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