Results 41 to 50 of about 62,967 (236)

Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos

open access: yesCells, 2021
Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation.
Jaeho Yoon   +6 more
doaj   +1 more source

Adhesive Crosstalk in Gastrulation [PDF]

open access: yesDevelopmental Cell, 2003
Recent studies show that signaling through integrin receptors is required for normal cell movements during Xenopus gastrulation. Integrins function in this process by modulating the activity of cadherin adhesion molecules within tissues undergoing convergence and extension movements.
Montero, J., Heisenberg, C.
openaire   +3 more sources

A Developmental Requirement for HIRA-Dependent H3.3 Deposition Revealed at Gastrulation in Xenopus

open access: yesCell Reports, 2012
Discovering how histone variants that mark distinct chromatin regions affect a developmental program is a major challenge in the epigenetics field. To assess the importance of the H3.3 histone variant and its dedicated histone chaperone HIRA, we used an ...
Emmanuelle Szenker   +2 more
doaj   +1 more source

Gastrulation in C. elegans [PDF]

open access: yesWormBook, 2005
Gastrulation is the process by which the germ layers become positioned in an embryo. C. elegans gastrulation serves as a model for studying the molecular mechanisms of diverse cellular and developmental phenomena, including morphogenesis, cell polarization, cell-cell signaling, actomyosin contraction and cell-cell adhesion.
Jeremy, Nance   +2 more
openaire   +2 more sources

Epigenetic regulator function through mouse gastrulation

open access: yesNature, 2020
During ontogeny, proliferating cells become restricted in their fate through the combined action of cell-type-specific transcription factors and ubiquitous epigenetic machinery, which recognizes universally available histone residues or nucleotides in a ...
Stefanie Grosswendt   +9 more
semanticscholar   +1 more source

Folded gastrulation and T48 drive the evolution of coordinated mesoderm internalization in flies

open access: yeseLife, 2016
Gastrulation constitutes a fundamental yet diverse morphogenetic process of metazoan development. Modes of gastrulation range from stochastic translocation of individual cells to coordinated infolding of an epithelial sheet.
Silvia Urbansky   +3 more
doaj   +1 more source

In vitro culture of cynomolgus monkey embryos beyond early gastrulation

open access: yesScience, 2019
In vitro development of monkey embryos Owing to technical and ethical limitations, the molecular and cellular mechanisms underlying primate gastrulation are far from clear (see the Perspective by Tam).
Huaixiao Ma   +12 more
semanticscholar   +1 more source

Actomyosin-based Self-organization of cell internalization during C. elegans gastrulation

open access: yesBMC Biology, 2012
Background Gastrulation is a key transition in embryogenesis; it requires self-organized cellular coordination, which has to be both robust to allow efficient development and plastic to provide adaptability.
Pohl Christian   +4 more
doaj   +1 more source

Retinoic Acid is Required for Normal Morphogenetic Movements During Gastrulation

open access: yesFrontiers in Cell and Developmental Biology, 2022
Retinoic acid (RA) is a central regulatory signal that controls numerous developmental processes in vertebrate embryos. Although activation of Hox expression is considered one of the earliest functions of RA signaling in the embryo, there is evidence ...
Michal Gur   +3 more
doaj   +1 more source

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]

open access: yesOpen Biology, 2020
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung   +5 more
doaj   +1 more source

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