Results 41 to 50 of about 81,569 (272)
Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]
Open Biology, 2020 Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung +5 more
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Furry is required for cell movements during gastrulation and functionally interacts with NDR1
Scientific Reports, 2021 Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes are established. Cell polarization is essential during gastrulation, driving asymmetric cell division, cell movements, and cell ...
Ailen S. Cervino +5 more
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Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo [PDF]
, 2006 Sphox11/13b is one of the two hox genes of Strongylocentrotus purpuratus expressed in the embryo. Its dynamic pattern of expression begins during gastrulation, when the transcripts are transiently located in a ring of cells at the edge of the ...
Arenas-Mena, César +2 more
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Hox genes control vertebrate body elongation by collinear Wnt repression
eLife, 2015 In vertebrates, the total number of vertebrae is precisely defined. Vertebrae derive from embryonic somites that are continuously produced posteriorly from the presomitic mesoderm (PSM) during body formation.
Nicolas Denans +2 more
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Gastrulation in C. elegans [PDF]
WormBook, 2005 Gastrulation is the process by which the germ layers become positioned in an embryo. C. elegans gastrulation serves as a model for studying the molecular mechanisms of diverse cellular and developmental phenomena, including morphogenesis, cell polarization, cell-cell signaling, actomyosin contraction and cell-cell adhesion.
Jeremy, Nance +2 more
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Substrate stiffness affects early differentiation events in embryonic stem cells [PDF]
European Cells & Materials, 2009 Embryonic stem cells (ESC) are both a potential source of cells for tissue replacement therapies and an accessible tool to model early embryonic development.
ND Evans +8 more
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Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula
eLife, 2017 During amphibian gastrulation, presumptive endoderm is internalised as part of vegetal rotation, a large-scale movement that encompasses the whole vegetal half of the embryo. It has been considered a gastrulation process unique to amphibians, but we show
Jason WH Wen, Rudolf Winklbauer
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Cells under Tension Drive Gastrulation [PDF]
Developmental Cell, 2020 In this issue of Developmental Cell, Muncie et al. describe the generation of gastrulation-like foci of cells within micropatterned colonies of pluripotent stem cells. This demonstration of mechanosensitive β-catenin/Wnt-dependent specification of cell fate during gastrulation illustrates the insights gleaned by placing stem cells in embryo-like ...
Clayton, Schwarz +1 more
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Nature Communications, 2023 Understanding of the molecular drivers of lineage diversification and tissue patterning during primary germ layer development requires in-depth knowledge of the dynamic molecular trajectories of cell lineages across a series of developmental stages of ...
Ran Wang +13 more
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Frontiers in Cell and Developmental Biology, 2023 The ancestral mode of left-right (L-R) patterning involves cilia in the L-R organizer. However, the mechanisms regulating L-R patterning in non-avian reptiles remains an enigma, since most squamate embryos are undergoing organogenesis at oviposition.
Natalia A. Shylo +6 more
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