Results 61 to 70 of about 69,462 (264)

Selective utilization of glucose metabolism guides mammalian gastrulation

Nature
The prevailing dogma for morphological patterning in developing organisms argues that the combined inputs of transcription factor networks and signalling morphogens alone generate spatially and temporally distinct expression patterns. However, metabolism
Dominica Cao, Jenna Bergmann, Liangwen Zhong, Anupama Hemalatha, Chaitanya Dingare, Tyler B. Jensen, Andy L Cox, Valentina Greco, B. Steventon, B. Sozen   +9 more
semanticscholar   +1 more source

In vitro culture of cynomolgus monkey embryos beyond early gastrulation

Science, 2019
In vitro development of monkey embryos Owing to technical and ethical limitations, the molecular and cellular mechanisms underlying primate gastrulation are far from clear (see the Perspective by Tam).
Huaixiao Ma, Jinglei Zhai, Haifeng Wan, Xiangxiang Jiang, Xiaoxiao Wang, Lin Wang, Yunlong Xiang, Xiechao He, Zhen-Ao Zhao, Bo Zhao, P. Zheng, Lei Li, Hongmei Wang   +12 more
semanticscholar   +1 more source

Gastrulation: Making and Shaping Germ Layers [PDF]

, 2012
Gastrulation is a fundamental phase of animal embryogenesis during which germ layers are specified, rearranged, and shaped into a body plan with organ rudiments.
Lila Solnica-Krezel, Diane S. Sepich
core   +1 more source

Gastrulation [PDF]

, 2015
Neural tube defects including spina bifida are common and severe congenital disorders. In mice, mutations in more than 200 genes can result in neural tube defects.
Jennifer K Heppert, Meserve, Joy H., Bob Goldstein, Sullivan-Brown, Jessica L., Tandon, Panna, Goldstein, Bob, Panna Tandon, Trogden, Kathryn P., Dickinson, Daniel J., Sophia C Tintori, Conlon, Frank L., Sara K Orlowski, Tintori, Sophia C., Heppert, Jennifer K., Kim E Bird, Daniel J Dickinson, Joy H Meserve, Frank L Conlon, Orlowski, Sara K., Jessica L Sullivan-Brown, Kathryn P Trogden, Bird, Kim E.   +21 more
core   +2 more sources

Retinoic Acid is Required for Normal Morphogenetic Movements During Gastrulation

Frontiers in Cell and Developmental Biology, 2022
Retinoic acid (RA) is a central regulatory signal that controls numerous developmental processes in vertebrate embryos. Although activation of Hox expression is considered one of the earliest functions of RA signaling in the embryo, there is evidence ...
Michal Gur, Tamir Edri, Sally A. Moody, Abraham Fainsod   +3 more
doaj   +1 more source

Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]

Open Biology, 2020
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung, Tsung-Ming Chen, Jing-Ping Lin, Yu-Ling Tai, Tang-Long Shen, Shyh-Jye Lee   +5 more
doaj   +1 more source

Hox genes control vertebrate body elongation by collinear Wnt repression

eLife, 2015
In vertebrates, the total number of vertebrae is precisely defined. Vertebrae derive from embryonic somites that are continuously produced posteriorly from the presomitic mesoderm (PSM) during body formation.
Nicolas Denans, Tadahiro Iimura, Olivier Pourquié   +2 more
doaj   +1 more source

Furry is required for cell movements during gastrulation and functionally interacts with NDR1

Scientific Reports, 2021
Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes are established. Cell polarization is essential during gastrulation, driving asymmetric cell division, cell movements, and cell ...
Ailen S. Cervino, Bruno Moretti, Carsten Stuckenholz, Hernán E. Grecco, Lance A. Davidson, M. Cecilia Cirio   +5 more
doaj   +1 more source

Bi-modal strategy of gastrulation in reptiles [PDF]

, 2016
[Background]: Amniote gastrulation is often described with respect to human, mouse and chick development by the presence of the primitive streak, a posterior-to-anterior midline morphological cell ingression feature that has come to define Amniote ...
Stower, Matthew J., Marco, Adolfo, Bertocchini, Federica, Srinivas, Shankar   +3 more
core   +1 more source

Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula

eLife, 2017
During amphibian gastrulation, presumptive endoderm is internalised as part of vegetal rotation, a large-scale movement that encompasses the whole vegetal half of the embryo. It has been considered a gastrulation process unique to amphibians, but we show
Jason WH Wen, Rudolf Winklbauer
doaj   +1 more source