Results 31 to 40 of about 62,161 (225)

Gastrulation: PARtaking of the Bottle [PDF]

open access: yesCurrent Biology, 2003
Gastrulation in C. elegans embryos involves ingression of individual cells, but is driven by apical constriction of the kind that promotes migration of epithelial cell sheets. Recent work shows that PAR proteins, known for their role in polarization and unequal cell division, are also associated with the polarization that establishes this apical ...
Putzke, Aaron P., Rothman, Joel H.
openaire   +3 more sources

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives

open access: yesCell Reports, 2017
Apela (also known as Elabela, Ende, and Toddler) is a small signaling peptide that activates the G-protein-coupled receptor Aplnr to stimulate cell migration during zebrafish gastrulation.
Laina Freyer   +10 more
doaj   +1 more source

Utilizing Playdoh in the Classroom to Construct a 3D Model Depicting Cellular Movements and Tissue Remodeling during Human Gastrulation, Early Organogenesis, and Embryonic Folding

open access: yesJournal of Microbiology & Biology Education, 2021
In classroom studies of mammalian embryology, students must fully grasp the cellular and tissue remodeling needed to initiate gastrulation to ensure comprehension of forthcoming developmental processes such as tissue specification and organogenesis ...
Ryan Hesterman   +6 more
doaj   +1 more source

Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus

open access: yesFrontiers in Physiology, 2018
Congenital heart disease (CHD) is the most common birth defect, yet its genetic causes continue to be obscure. Fibroblast growth factor receptor 4 (FGFR4) recently emerged in a large patient exome sequencing study as a candidate disease gene for CHD and ...
Emily Sempou   +3 more
doaj   +1 more source

Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation

open access: yeseLife, 2022
Cells sense and integrate external information from diverse sources that include mechanical cues. Shaping of tissues during development may thus require coordination between mechanical forces from morphogenesis and cell-cell signalling to confer ...
Julia Falo-Sanjuan, Sarah Bray
doaj   +1 more source

Inhibition of the synthesis of glycosphingolipid by a ceramide analogue (PPMP) in the gastrulation of Bufo arenarum [PDF]

open access: yes, 2000
In the present study the role of glycosphingolipids (GSL) in amphibian development was investigated. We analysed the de novo synthesis of neutral GSL and gangliosides through the initial stages of Bufo arenarnm embryo development and their participation ...
Analía Fuentes   +5 more
core   +1 more source

scRNAseq toy dataset of mouse gastrulation

open access: yes, 2021
A single-cell molecular map of mouse gastrulation and early organogenesis (aka mouse gastrulation atlas)
Elyas Heidari (11811722)
core   +1 more source

Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos

open access: yesCells, 2021
Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation.
Jaeho Yoon   +6 more
doaj   +1 more source

Gastrulation in C. elegans [PDF]

open access: yesWormBook, 2005
Gastrulation is the process by which the germ layers become positioned in an embryo. C. elegans gastrulation serves as a model for studying the molecular mechanisms of diverse cellular and developmental phenomena, including morphogenesis, cell polarization, cell-cell signaling, actomyosin contraction and cell-cell adhesion.
Jeremy, Nance   +2 more
openaire   +2 more sources

A Developmental Requirement for HIRA-Dependent H3.3 Deposition Revealed at Gastrulation in Xenopus

open access: yesCell Reports, 2012
Discovering how histone variants that mark distinct chromatin regions affect a developmental program is a major challenge in the epigenetics field. To assess the importance of the H3.3 histone variant and its dedicated histone chaperone HIRA, we used an ...
Emmanuelle Szenker   +2 more
doaj   +1 more source

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