Results 31 to 40 of about 62,969 (218)

Dynamics of Sea Urchin Gastrulation Revealed by Tracking Cells of Diverse Lineage and Regulatory State [PDF]

open access: yes, 2011
During gastrulation in the sea urchin embryo the archenteron, or primitive gut, is formed by an initial process of invagination at the vegetal pole of the embryo, followed by extension across the blastocoel toward the future mouth.
Barnet, Matthew Edward
core   +1 more source

A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis

open access: yeseLife, 2021
Metastasis is responsible for approximately 90% of cancer-associated mortality but few models exist that allow for rapid and effective screening of anti-metastasis drugs.
Joji Nakayama   +6 more
doaj   +1 more source

Cell Polarity and Morphogenesis: Functions and Mechanisms of Cell Divisions in Vertebrate Gastrulation [PDF]

open access: yes, 2004
Gastrulation shapes a vertebrate embryo from an egg-shaped aggregate of cells. In many vertebrates, massive cell divisions occur during gastrulation. In this thesis, I investigate the pattern, function, and regulation of mitotic divisions in zebrafish ...
Gong, Ying, Ying Gong
core   +1 more source

The cessation of gastrulation [PDF]

open access: yesCell Adhesion & Migration, 2010
An integral component of gastrulation in all organisms is epithelial to mesenchymal transition (EMT), a fundamental morphogenetic event through which epithelial cells transform into mesenchymal cells. The mesenchymal cells that arise from epithelial cells during gastrulation contribute to various tissue rudiments during subsequent development ...
Sho, Ohta   +2 more
openaire   +2 more sources

Live imaging of whole mouse embryos during gastrulation : migration analyses of epiblast and mesodermal cells [PDF]

open access: yes, 2013
During gastrulation in the mouse embryo, dynamic cell movements including epiblast invagination and mesodermal layer expansion lead to the establishment of the three-layered body plan.
Kenichi Nakazato (431530)   +27 more
core   +2 more sources

scRNAseq toy dataset of mouse gastrulation

open access: yes, 2021
A single-cell molecular map of mouse gastrulation and early organogenesis (aka mouse gastrulation atlas)
Elyas Heidari (11811722)
core   +1 more source

Gastrulation: PARtaking of the Bottle [PDF]

open access: yesCurrent Biology, 2003
Gastrulation in C. elegans embryos involves ingression of individual cells, but is driven by apical constriction of the kind that promotes migration of epithelial cell sheets. Recent work shows that PAR proteins, known for their role in polarization and unequal cell division, are also associated with the polarization that establishes this apical ...
Putzke, Aaron P., Rothman, Joel H.
openaire   +3 more sources

Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus

open access: yesFrontiers in Physiology, 2018
Congenital heart disease (CHD) is the most common birth defect, yet its genetic causes continue to be obscure. Fibroblast growth factor receptor 4 (FGFR4) recently emerged in a large patient exome sequencing study as a candidate disease gene for CHD and ...
Emily Sempou   +3 more
doaj   +1 more source

Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation

open access: yeseLife, 2022
Cells sense and integrate external information from diverse sources that include mechanical cues. Shaping of tissues during development may thus require coordination between mechanical forces from morphogenesis and cell-cell signalling to confer ...
Julia Falo-Sanjuan, Sarah Bray
doaj   +1 more source

Bmp Signal Gradient Modulates Convergent Cell Movement via Xarhgef3.2 during Gastrulation of Xenopus Embryos

open access: yesCells, 2021
Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation.
Jaeho Yoon   +6 more
doaj   +1 more source

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