Results 11 to 20 of about 81,569 (272)
Stem Cell Reports, 2023 Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul +8 more
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Biology Open, 2022 Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis.
Tingxu Chen +6 more
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eLife, 2020 Ventral furrow formation, the first step in Drosophila gastrulation, is a well-studied example of tissue morphogenesis. Rho1 is highly active in a subset of ventral cells and is required for this morphogenetic event.
Ashley Rich +2 more
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Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation [PDF]
, 2017 Cell proliferation has generally been considered dispensable for anteroposterior extension of embryonic axis during vertebrate gastrulation. Signal transducer and activator of transcription 3 (Stat3), a conserved controller of cell proliferation ...
Liu, Yinzi +2 more
core +8 more sources
Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation
eLife, 2022 Cells sense and integrate external information from diverse sources that include mechanical cues. Shaping of tissues during development may thus require coordination between mechanical forces from morphogenesis and cell-cell signalling to confer ...
Julia Falo-Sanjuan, Sarah Bray
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Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. [PDF]
PLoS ONE, 2018 Gastrulation is the initial systematic deformation of the embryo to form germ layers, which is characterized by the placement of appropriate cells in their destined locations.
Yuta Yamamoto +8 more
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The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish
Biology, 2021 Cell adhesion and polarized cellular behaviors play critical roles in a wide variety of morphogenetic events. In the zebrafish embryo, epiboly represents an important process of epithelial morphogenesis that involves differential cell adhesion and ...
Ji-Tong Li +4 more
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eLife, 2021 Metastasis is responsible for approximately 90% of cancer-associated mortality but few models exist that allow for rapid and effective screening of anti-metastasis drugs.
Joji Nakayama +6 more
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Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation [PDF]
, 2004 During amphibian gastrulation, the embryo is transformed by the combined actions of several different tissues. Paradoxically, many of these morphogenetic processes can occur autonomously in tissue explants, yet the tissues in intact embryos must interact
Ewald, Andrew J. +4 more
core +2 more sources
Ptenb mediates gastrulation cell movements via Cdc42/AKT1 in zebrafish.
PLoS ONE, 2011 Phosphatidylinositol 3-kinase (PI3 kinase) mediates gastrulation cell migration in zebrafish via its regulation of PIP(2)/PIP(3) balance. Although PI3 kinase counter enzyme PTEN has also been reported to be essential for gastrulation, its role in ...
Chen-Min Yeh +5 more
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