Results 11 to 20 of about 62,161 (225)

The evolution of gastrulation morphologies [PDF]

Development, 2023
ABSTRACTDuring gastrulation, early embryos specify and reorganise the topology of their germ layers. Surprisingly, this fundamental and early process does not appear to be rigidly constrained by evolutionary pressures; instead, the morphology of gastrulation is highly variable throughout the animal kingdom.
Serrano Nájera, Guillermo, Weijer, Cornelis J   +1 more
core   +8 more sources

Actomyosin-based Self-organization of cell internalization during C. elegans gastrulation [PDF]

BMC Biology, 2012
Background Gastrulation is a key transition in embryogenesis; it requires self-organized cellular coordination, which has to be both robust to allow efficient development and plastic to provide adaptability.
Pohl Christian, Tiongson Michael, Moore Julia L, Santella Anthony, Bao Zhirong   +4 more
doaj   +2 more sources

Adhesive Crosstalk in Gastrulation [PDF]

Developmental Cell, 2003
Recent studies show that signaling through integrin receptors is required for normal cell movements during Xenopus gastrulation. Integrins function in this process by modulating the activity of cadherin adhesion molecules within tissues undergoing convergence and extension movements.
Montero, J., Heisenberg, C.
openaire   +5 more sources

Ptenb mediates gastrulation cell movements via Cdc42/AKT1 in zebrafish.

PLoS ONE, 2011
Phosphatidylinositol 3-kinase (PI3 kinase) mediates gastrulation cell migration in zebrafish via its regulation of PIP(2)/PIP(3) balance. Although PI3 kinase counter enzyme PTEN has also been reported to be essential for gastrulation, its role in ...
Chen-Min Yeh, Yi-Ching Liu, Ching-Jen Chang, Shih-Lei Lai, Chung-Der Hsiao, Shyh-Jye Lee   +5 more
doaj   +2 more sources

A single-cell atlas of pig gastrulation as a resource for comparative embryology [PDF]

Nature Communications
Cell-fate decisions during mammalian gastrulation are poorly understood outside of rodent embryos. The embryonic disc of pig embryos mirrors humans, making them a useful proxy for studying gastrulation.
Luke Simpson, Andrew Strange, Doris Klisch, Sophie Kraunsoe, Takuya Azami, Daniel Goszczynski, Triet Le Minh, Benjamin Planells, Nadine Holmes, Fei Sang, Sonal Henson, Matthew Loose, Jennifer Nichols, Ramiro Alberio   +13 more
doaj   +2 more sources

tanaylab/tet-gastrulation: V1.0.0

, 2022
TET gastrulation paper analysis ...
mmittnenzweig, Aviezer Lifshitz
core   +1 more source

seqFish toy dataset of mouse gastrulation

, 2021
Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis (aka spatial mouse gastrulation atlas ...
Elyas Heidari (11811722)
core   +6 more sources

Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. [PDF]

PLoS ONE, 2018
Gastrulation is the initial systematic deformation of the embryo to form germ layers, which is characterized by the placement of appropriate cells in their destined locations.
Yuta Yamamoto, Shota Miyazaki, Kenshiro Maruyama, Ryo Kobayashi, Minh Nguyen Tuyet Le, Ayumu Kano, Akiko Kondow, Shuji Fujii, Kiyoshi Ohnuma   +8 more
doaj   +1 more source

A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis

eLife, 2021
Metastasis is responsible for approximately 90% of cancer-associated mortality but few models exist that allow for rapid and effective screening of anti-metastasis drugs.
Joji Nakayama, Lora Tan, Yan Li, Boon Cher Goh, Shu Wang, Hideki Makinoshima, Zhiyuan Gong   +6 more
doaj   +1 more source

Dynamics of Sea Urchin Gastrulation Revealed by Tracking Cells of Diverse Lineage and Regulatory State [PDF]

, 2011
During gastrulation in the sea urchin embryo the archenteron, or primitive gut, is formed by an initial process of invagination at the vegetal pole of the embryo, followed by extension across the blastocoel toward the future mouth.
Barnet, Matthew Edward
core   +1 more source