Results 21 to 30 of about 69,462 (264)

Tunicate gastrulation [PDF]

open access: yes, 2020
Tunicates are a diverse group of invertebrate marine chordates that includes the larvaceans, thaliaceans, and ascidians. Because of their unique evolutionary position as the sister group of the vertebrates, tunicates are invaluable as a comparative model and hold the promise of revealing both conserved and derived features of chordate gastrulation ...
Konner M, Winkley   +4 more
openaire   +2 more sources

Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD

open access: yesFrontiers in Cell and Developmental Biology, 2023
Fetal Alcohol Spectrum Disorder (FASD) arises from maternal consumption of alcohol during pregnancy affecting 2%–5% of the Western population. In Xenopus laevis studies, we showed that alcohol exposure during early gastrulation reduces retinoic acid (RA)
B. Petrelli   +5 more
doaj   +1 more source

Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies

open access: yesStem Cell Reports, 2023
Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul   +8 more
doaj   +1 more source

A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation

open access: yesBiology Open, 2022
Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis.
Tingxu Chen   +6 more
doaj   +1 more source

Primate gastrulation and early organogenesis at single-cell resolution

open access: yesNature, 2022
Our understanding of human early development is severely hampered by limited access to embryonic tissues. Due to their close evolutionary relationship with humans, nonhuman primates are often used as surrogates to understand human development but ...
Jinglei Zhai   +16 more
semanticscholar   +1 more source

Rho1 activation recapitulates early gastrulation events in the ventral, but not dorsal, epithelium of Drosophila embryos

open access: yeseLife, 2020
Ventral furrow formation, the first step in Drosophila gastrulation, is a well-studied example of tissue morphogenesis. Rho1 is highly active in a subset of ventral cells and is required for this morphogenetic event.
Ashley Rich   +2 more
doaj   +1 more source

scRNAseq toy dataset of mouse gastrulation [PDF]

open access: yes, 2021
A single-cell molecular map of mouse gastrulation and early organogenesis (aka mouse gastrulation atlas)
Elyas Heidari (11811722)
core   +1 more source

Human embryonic development: from peri-implantation to gastrulation.

open access: yesTrends in Cell Biology, 2021
The basic body plan of the mammalian embryo is established through gastrulation, a pivotal early postimplantation event during which the three major germ layers (endoderm, ectoderm, and mesoderm) are specified with cellular and spatial diversity. Despite
Jinglei Zhai   +3 more
semanticscholar   +1 more source

The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish

open access: yesBiology, 2021
Cell adhesion and polarized cellular behaviors play critical roles in a wide variety of morphogenetic events. In the zebrafish embryo, epiboly represents an important process of epithelial morphogenesis that involves differential cell adhesion and ...
Ji-Tong Li   +4 more
doaj   +1 more source

Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. [PDF]

open access: yesPLoS ONE, 2018
Gastrulation is the initial systematic deformation of the embryo to form germ layers, which is characterized by the placement of appropriate cells in their destined locations.
Yuta Yamamoto   +8 more
doaj   +1 more source

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