Results 21 to 30 of about 62,967 (236)
Embryo model completes gastrulation to neurulation and organogenesis
Nature, 2022 Embryonic stem (ES) cells can undergo many aspects of mammalian embryogenesis in vitro1–5, but their developmental potential is substantially extended by interactions with extraembryonic stem cells, including trophoblast stem (TS) cells, extraembryonic ...
G. Amadei +14 more
semanticscholar +1 more source
Early human embryonic development: Blastocyst formation to gastrulation.
Developmental Cell, 2022 There has been recent renewed interest in studying human early embryonic development. The advent of improved culture conditions to maintain blastocysts in vitro for an extended period and the emerging stem-cell-based models of the blastocyst and peri ...
J. Rossant, P. Tam
semanticscholar +1 more source
, 2020 Tunicates are a diverse group of invertebrate marine chordates that includes the larvaceans, thaliaceans, and ascidians. Because of their unique evolutionary position as the sister group of the vertebrates, tunicates are invaluable as a comparative model and hold the promise of revealing both conserved and derived features of chordate gastrulation ...
Konner M, Winkley +4 more
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2023 Fetal Alcohol Spectrum Disorder (FASD) arises from maternal consumption of alcohol during pregnancy affecting 2%–5% of the Western population. In Xenopus laevis studies, we showed that alcohol exposure during early gastrulation reduces retinoic acid (RA)
B. Petrelli +5 more
doaj +1 more source
Stem Cell Reports, 2023 Summary: The mechanism by which morphogenetic signals engage the regulatory networks responsible for early embryonic tissue patterning is incompletely understood.
Himanshu Kaul +8 more
doaj +1 more source
Biology Open, 2022 Formation of a properly sized and patterned embryo during gastrulation requires a well-coordinated interplay between cell proliferation, lineage specification and tissue morphogenesis.
Tingxu Chen +6 more
doaj +1 more source
Primate gastrulation and early organogenesis at single-cell resolution
Nature, 2022 Our understanding of human early development is severely hampered by limited access to embryonic tissues. Due to their close evolutionary relationship with humans, nonhuman primates are often used as surrogates to understand human development but ...
Jinglei Zhai +16 more
semanticscholar +1 more source
eLife, 2020 Ventral furrow formation, the first step in Drosophila gastrulation, is a well-studied example of tissue morphogenesis. Rho1 is highly active in a subset of ventral cells and is required for this morphogenetic event.
Ashley Rich +2 more
doaj +1 more source
The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish
Biology, 2021 Cell adhesion and polarized cellular behaviors play critical roles in a wide variety of morphogenetic events. In the zebrafish embryo, epiboly represents an important process of epithelial morphogenesis that involves differential cell adhesion and ...
Ji-Tong Li +4 more
doaj +1 more source
Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. [PDF]
PLoS ONE, 2018 Gastrulation is the initial systematic deformation of the embryo to form germ layers, which is characterized by the placement of appropriate cells in their destined locations.
Yuta Yamamoto +8 more
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