Results 21 to 30 of about 81,569 (272)
Molecular anatomy of the pre-primitive-streak chick embryo [PDF]
Open Biology, 2020 The early stages of development of the chick embryo, leading to primitive streak formation (the start of gastrulation), have received renewed attention recently, especially for studies of the mechanisms of large-scale cell movements and those that ...
Hyung Chul Lee +6 more
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eLife, 2022 The morphogenic process of convergent thickening (CT) was originally described as the mediolateral convergence and radial thickening of the explanted ventral involuting marginal zone (IMZ) of Xenopus gastrulae (Keller and Danilchik, 1988).
David R Shook +9 more
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Rab7 is required for mesoderm patterning and gastrulation in Xenopus
Biology Open, 2021 Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis +2 more
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Imaging in Spinal DysraphismA Pictoral Assay [PDF]
International Journal of Anatomy Radiology and Surgery, 2021 Spinal dysraphism includes the congenital malformations of the spine and spinal cord. Spinal cord development takes place through successive stages of gastrulation, primary neurulation, and secondary neurulation. Defect in any of these three phases can
Anurudh Kishore Vatti +2 more
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Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids. [PDF]
, 2019 During gastrulation, the pluripotent epiblast self-organizes into the 3 germ layers-endoderm, mesoderm and ectoderm, which eventually form the entire embryo.
Chhabra, Sapna +4 more
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eLife, 2018 In vivo, the primary molecular mechanotransductive events mechanically initiating cell differentiation remain unknown. Here we find the molecular stretching of the highly conserved Y654-β-catenin-D665-E-cadherin binding site as mechanically induced by ...
Jens-Christian Röper +8 more
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Quo vadis PGRMC? Grand-Scale Biology in Human Health and Disease
Frontiers in Bioscience-Landmark, 2022 The title usage of Latin Quo vadis ‘where are you going’ extends the question Unde venisti from where ‘did you come?’ posed in the accompanying paper and extends consideration of how ancient eukaryotic and eumetazoan functions of progesterone receptor ...
Michael A. Cahill
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Frontiers in Cell and Developmental Biology, 2019 The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity (TC). Here, I focus on the two current
Antony J. Durston
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Cell Reports, 2017 Apela (also known as Elabela, Ende, and Toddler) is a small signaling peptide that activates the G-protein-coupled receptor Aplnr to stimulate cell migration during zebrafish gastrulation.
Laina Freyer +10 more
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Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus
Frontiers in Physiology, 2018 Congenital heart disease (CHD) is the most common birth defect, yet its genetic causes continue to be obscure. Fibroblast growth factor receptor 4 (FGFR4) recently emerged in a large patient exome sequencing study as a candidate disease gene for CHD and ...
Emily Sempou +3 more
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