Results 91 to 100 of about 81,543 (257)

Zebrafish embryonic explants undergo genetically encoded self-assembly

open access: yeseLife, 2020
Embryonic stem cell cultures are thought to self-organize into embryoid bodies, able to undergo symmetry-breaking, germ layer specification and even morphogenesis.
Alexandra Schauer   +3 more
doaj   +1 more source

Epiblast morphogenesis before gastrulation

open access: yesDevelopmental Biology, 2015
The epiblast is a single cell-layered epithelium which generates through gastrulation all tissues in an amniote embryo proper. Specification of the epiblast as a cell lineage in early development is coupled with that of the trophoblast and hypoblast, two lineages dedicated to forming extramebryonic tissues.
openaire   +2 more sources

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Spatial and temporal patterns of distribution of the gap junction protein connexin43 during mouse gastrulation and organogenesis [PDF]

open access: yes, 1992
Connexin43 (Cx43) is a member of the family of channel-forming proteins that make up the gap junction and are believed to provide pathways for cell-cell exchange of developmental signals.
Biswal, Sandip   +2 more
core  

Evolutionary plasticity of developmental gene regulatory network architecture [PDF]

open access: yes, 2007
Sea stars and sea urchins evolved from a last common ancestor that lived at the end of the Cambrian, approximately half a billion years ago. In a previous comparative study of the gene regulatory networks (GRNs) that embody the genomic program for ...
Britten   +25 more
core   +4 more sources

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

open access: yesImmunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic   +2 more
wiley   +1 more source

Macromere cell fates during sea urchin development [PDF]

open access: yes, 1991
This paper examines the cell lineage relationships and cell fates in embryos of the sea urchin Strongylocentrotus purpuratus leading to the various cell types derived from the definitive vegetal plate territory or the veg_2 tier of cells.
Britten, Roy J.   +3 more
core  

Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon   +6 more
wiley   +1 more source

May the force be with you

open access: yeseLife, 2018
Understanding the coordination of the forces generated in embryos by two processes, convergent extension and convergent thickening, is key to understanding how a hollow sphere of cells develops into an elongated embryo.
Shinuo Weng, John B Wallingford
doaj   +1 more source

Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling

open access: yesBrain and Behavior, Volume 16, Issue 2, February 2026.
Histone methylation and acetylation modulate gene expression by inducing chromatin condensation or relaxation, which in turn regulates transcriptional activity and impacts neurogenesis. ABSTRACT Aims The purpose of this review is to examine how epigenetic regulation particularly chromatin modification and histone methylation controls gene expression ...
Degisew Yinur Mengistu   +1 more
wiley   +1 more source

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