Results 101 to 110 of about 81,543 (257)

Large, long range tensile forces drive convergence during Xenopus blastopore closure and body axis elongation

open access: yeseLife, 2018
Indirect evidence suggests that blastopore closure during gastrulation of anamniotes, including amphibians such as Xenopus laevis, depends on circumblastoporal convergence forces generated by the marginal zone (MZ), but direct evidence is lacking.
David R Shook   +3 more
doaj   +1 more source

Pre‐oviposition development of the brown anole (Anolis sagrei)

open access: yesDevelopmental Dynamics, Volume 255, Issue 2, Page 145-167, February 2026.
Abstract Background The brown anole, Anolis sagrei, has emerged as a representative squamate species for developmental studies during the past decades. Novel functional tools have been established to manipulate embryogenesis through genome editing or the introduction of small molecule inhibitors, and their effective use requires a thorough ...
Antonia Weberling   +9 more
wiley   +1 more source

Egg quality markers in domesticated broodstock of Atlantic halibut (Hippoglossus hippoglossus) with relevance for optimization of hatchery protocols

open access: yesFrontiers in Aquaculture
IntroductionCommercial production of Atlantic halibut (Hippoglossus hippoglossus) has many obstacles, such as low and highly variable egg quality and survival rates during early developmental stages.
Nils Niepagen   +3 more
doaj   +1 more source

Pitx2c orchestrates embryonic axis extension via mesendodermal cell migration

open access: yeseLife, 2018
Pitx2c, a homeodomain transcription factor, is classically known for its left-right patterning role. However, an early wave of pitx2 expression occurs at the onset of gastrulation in several species, indicating a possible earlier role that remains ...
Michelle M Collins   +5 more
doaj   +1 more source

Linear signaling in the Toll-Dorsal pathway of Drosophila: activated Pelle kinase specifies all threshold outputs of gene expression while the bHLH protein Twist specifies a subset [PDF]

open access: yes, 2002
Differential activation of the Toll receptor leads to the formation of a broad Dorsal nuclear gradient that specifies at least three patterning thresholds of gene activity along the dorsoventral axis of precellular embryos.
Levine, Michael, Stathopoulos, Angelike
core  

Mosaic Li Fraumeni Syndrome Not Identified in Germinal Tissue

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 2, February 2026.
In this study, we presented the first clinical case report of mosaic Li Fraumeni syndrome eluding germinal tissue. This case highlights the complexity of interpreting mosaic variants in TP53, and the difficulty in relaying cancer and reproductive risk information in the context of mosaic Li Fraumeni syndrome.
Rhianna M. Urban   +9 more
wiley   +1 more source

The transcription factor Pitx2 positions the embryonic axis and regulates twinning

open access: yeseLife, 2014
Embryonic polarity of invertebrates, amphibians and fish is specified largely by maternal determinants, which fixes cell fates early in development. In contrast, amniote embryos remain plastic and can form multiple individuals until gastrulation.
Angela Torlopp   +6 more
doaj   +1 more source

Gastrulation in the sea urchin

open access: yes, 2020
Gastrulation is arguably the most important evolutionary innovation in the animal kingdom. This process provides the basic embryonic architecture, an inner layer separated from an outer layer, from which all animal forms arise. An extraordinarily simple and elegant process of gastrulation is observed in the sea urchin embryo. The cells participating in
McClay, David R.   +4 more
openaire   +4 more sources

Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo

open access: yeseLife, 2019
In mouse embryo gastrulation, epiblast cells delaminate at the primitive streak to form mesoderm and definitive endoderm, through an epithelial-mesenchymal transition.
Bechara Saykali   +6 more
doaj   +1 more source

Intercellular Bridges in Vertebrate Gastrulation

open access: yesPLoS ONE, 2011
The developing zebrafish embryo has been the subject of many studies of regional patterning, stereotypical cell movements and changes in cell shape. To better study the morphological features of cells during gastrulation, we generated mosaic embryos expressing membrane attached Dendra2 to highlight cellular boundaries.
Caneparo, L   +3 more
openaire   +6 more sources

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