Results 101 to 110 of about 10,115 (192)

The Gastrulation of the Egg of Bufo lentiginosus [PDF]

The American Naturalist, 1902
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openaire   +2 more sources

The ceramide synthase 2b gene mediates genomic sensing and regulation of sphingosine levels during zebrafish embryogenesis

eLife, 2017
Sphingosine-1-phosphate (S1P) is generated through phosphorylation of sphingosine by sphingosine kinases (Sphk1 and Sphk2). We show that sphk2 maternal-zygotic mutant zebrafish embryos (sphk2MZ) display early developmental phenotypes, including a delay ...
Karen Mendelson, Suveg Pandey, Yu Hisano, Frank Carellini, Bhaskar C Das, Timothy Hla, Todd Evans   +6 more
doaj   +1 more source

Loss of 18q Alters TGFβ Signalling Affecting Anteroposterior Neuroectodermal Fate in Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
hESCsdel18q exhibit delayed and impaired anterior neuroectoderm induction, leading to deficient RPE specification. hESCsdel18q lines showed dysregulation of TGFβ signalling, and endogenous overactivation of activin/nodal/TGFβ in hESCsdel18q leads to improper anterior/posterior neuroectodermal fate commitments.
Yingnan Lei, Mai Chi Duong, Nuša Krivec, Charlotte Janssens, Marius Regin, Anfien Huyghebaert, Edouard Couvreu de Deckersberg, Karen Sermon, Diana Al Delbany, Claudia Spits   +9 more
wiley   +1 more source

Advances in the Study of Pluripotent Stem Cells in Livestock

Cell Proliferation, EarlyView.
Livestock pluripotent stem cells include embryonic stem cells (ESCs) isolated from the inner cell mass of blastocysts and induced pluripotent stem cells (iPSCs) derived from somatic cell reprogramming. They hold significant potential for applications in livestock breed improvement, rapid propagation, human disease modelling and human organ ...
Xinyi Zhou, Chen Gao, Wenxuan Zhao, Xinhua Wei, Dawei Yu, Huiying Zou, Weihua Du   +6 more
wiley   +1 more source

Morphological and Gene Expression Changes in Cattle Embryos from Hatched Blastocyst to Early Gastrulation Stages after Transfer of In Vitro Produced Embryos

PLoS ONE, 2015
A detailed morphological staging system for cattle embryos at stages following blastocyst hatching and preceding gastrulation is presented here together with spatiotemporal mapping of gene expression for BMP4, BRACHYURY, CERBERUS1 (CER1), CRIPTO ...
J. van Leeuwen, D. Berg, P. Pfeffer
semanticscholar   +1 more source

Transcriptome Analysis Suggested Striking Transition Around the End of Epiboly in the Gene Regulatory Network Downstream of the Oct4‐Type POU Gene in Zebrafish Embryos

Development, Growth &Differentiation, Volume 67, Issue 5, Page 245-269, June 2025.
Transcriptome analysis of pou5f3‐regulated genes in zebrafish embryos showed that competence to pou5f3 regulation changes significantly before and after the end of epiboly. The target genes encoded a diverse array of proteins, including transcriptional regulators and signaling molecules.
Masaaki Ikeda, Kana Kobayashi, Yukiko Nakayama‐Sadakiyo, Yuto Sato, Ayano Tobita, Mika Saito, Kyo Yamasu   +6 more
wiley   +1 more source

Quantitative imaging reveals real-time Pou5f3–Nanog complexes driving dorsoventral mesendoderm patterning in zebrafish

eLife, 2016
Formation of the three embryonic germ layers is a fundamental developmental process that initiates differentiation. How the zebrafish pluripotency factor Pou5f3 (homologous to mammalian Oct4) drives lineage commitment is unclear.
Mireia Perez-Camps, Jing Tian, Serene C Chng, Kai Pin Sem, Thankiah Sudhaharan, Cathleen Teh, Malte Wachsmuth, Vladimir Korzh, Sohail Ahmed, Bruno Reversade   +9 more
doaj   +1 more source

kcnb1 loss of function in zebrafish causes neurodevelopmental and epileptic disorders associated with γ‐aminobutyric acid dysregulation

Epilepsia, EarlyView.
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon, Claire Bar, Anca Marian, Lisa Lehmann, Solène Renault, Edor Kabashi, Sorana Ciura, Rima Nabbout   +7 more
wiley   +1 more source

Identification of Binding Proteins in Xenopus laevis by MALDI-TOF/TOF Mass Spectrometry

Journal of Analytical Science and Technology, 2010
MALDI-TOF/TOF MS has been widely used for the identification of proteins in the proteomics field. Here we tried to identify novel proteins during vertebrate development by this MS and targeted the protein binding to Xenopus β-arrestin 2 (xβarr2).
Edmond Changkyun Park, MiJung Kim, Jae Yeon Hur, Zee-Won Lee, Jin-Kwan Han, Gun-Hwa Kim   +5 more
doaj  

Spiralian gastrulation: germ layer formation, morphogenesis, and fate of the blastopore in the slipper snail Crepidula fornicata

EvoDevo, 2015
Gastrulation is a critical step in bilaterian development, directly linked to the segregation of germ layers, establishment of axes, and emergence of the through-gut.
D. C. Lyons, Kimberly J. Perry, J. Henry
semanticscholar   +1 more source