Results 21 to 30 of about 50,858 (171)
Apela (also known as Elabela, Ende, and Toddler) is a small signaling peptide that activates the G-protein-coupled receptor Aplnr to stimulate cell migration during zebrafish gastrulation.
Laina Freyer +10 more
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In classroom studies of mammalian embryology, students must fully grasp the cellular and tissue remodeling needed to initiate gastrulation to ensure comprehension of forthcoming developmental processes such as tissue specification and organogenesis ...
Ryan Hesterman +6 more
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Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus
Congenital heart disease (CHD) is the most common birth defect, yet its genetic causes continue to be obscure. Fibroblast growth factor receptor 4 (FGFR4) recently emerged in a large patient exome sequencing study as a candidate disease gene for CHD and ...
Emily Sempou +3 more
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Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation.
Jaeho Yoon +6 more
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Folded gastrulation and T48 drive the evolution of coordinated mesoderm internalization in flies
Gastrulation constitutes a fundamental yet diverse morphogenetic process of metazoan development. Modes of gastrulation range from stochastic translocation of individual cells to coordinated infolding of an epithelial sheet.
Silvia Urbansky +3 more
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Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung +5 more
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Retinoic Acid is Required for Normal Morphogenetic Movements During Gastrulation
Retinoic acid (RA) is a central regulatory signal that controls numerous developmental processes in vertebrate embryos. Although activation of Hox expression is considered one of the earliest functions of RA signaling in the embryo, there is evidence ...
Michal Gur +3 more
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Actomyosin-based Self-organization of cell internalization during
Background Gastrulation is a key transition in embryogenesis; it requires self-organized cellular coordination, which has to be both robust to allow efficient development and plastic to provide adaptability.
Pohl Christian +4 more
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Furry is required for cell movements during gastrulation and functionally interacts with NDR1
Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes are established. Cell polarization is essential during gastrulation, driving asymmetric cell division, cell movements, and cell ...
Ailen S. Cervino +5 more
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Hox genes control vertebrate body elongation by collinear Wnt repression
In vertebrates, the total number of vertebrae is precisely defined. Vertebrae derive from embryonic somites that are continuously produced posteriorly from the presomitic mesoderm (PSM) during body formation.
Nicolas Denans +2 more
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