Results 21 to 30 of about 10,115 (192)

Notch-dependent and -independent transcription are modulated by tissue movements at gastrulation

eLife, 2022
Cells sense and integrate external information from diverse sources that include mechanical cues. Shaping of tissues during development may thus require coordination between mechanical forces from morphogenesis and cell-cell signalling to confer ...
Julia Falo-Sanjuan, Sarah Bray
doaj   +1 more source

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Biology Open, 2021
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis, Fee M. Wielath, Philipp Vick   +2 more
doaj   +1 more source

Random migration of induced pluripotent stem cell-derived human gastrulation-stage mesendoderm. [PDF]

PLoS ONE, 2018
Gastrulation is the initial systematic deformation of the embryo to form germ layers, which is characterized by the placement of appropriate cells in their destined locations.
Yuta Yamamoto, Shota Miyazaki, Kenshiro Maruyama, Ryo Kobayashi, Minh Nguyen Tuyet Le, Ayumu Kano, Akiko Kondow, Shuji Fujii, Kiyoshi Ohnuma   +8 more
doaj   +1 more source

The cessation of gastrulation [PDF]

Cell Adhesion & Migration, 2010
An integral component of gastrulation in all organisms is epithelial to mesenchymal transition (EMT), a fundamental morphogenetic event through which epithelial cells transform into mesenchymal cells. The mesenchymal cells that arise from epithelial cells during gastrulation contribute to various tissue rudiments during subsequent development ...
Gen Yamada, Gary C. Schoenwolf, Sho Ohta
openaire   +3 more sources

Utilizing Playdoh in the Classroom to Construct a 3D Model Depicting Cellular Movements and Tissue Remodeling during Human Gastrulation, Early Organogenesis, and Embryonic Folding

Journal of Microbiology & Biology Education, 2021
In classroom studies of mammalian embryology, students must fully grasp the cellular and tissue remodeling needed to initiate gastrulation to ensure comprehension of forthcoming developmental processes such as tissue specification and organogenesis ...
Ryan Hesterman, Shannon Rose, Will LeFever, Ryan Stewart, Martina Krone, Camryn Holihan, Kristin Ackerman   +6 more
doaj   +1 more source

A mechanochemical model recapitulates distinct vertebrate gastrulation modes

bioRxiv, 2021
Gastrulation is a critical event in vertebrate morphogenesis driven by cellular processes, and characterized by coordinated multi-cellular movements that form the robust morphological structures.
M. Serra, Guillermo Serrano Nájera, Manli Chuai, Alex M. Plum, Sreejith Santhosh, V. Spandan, Cornelis J. Weijer, L. Mahadevan   +7 more
semanticscholar   +1 more source

Reconstruction of distinct vertebrate gastrulation modes via modulation of key cell behaviors in the chick embryo

bioRxiv, 2021
The morphology of gastrulation driving the internalisation of the mesoderm and endoderm differs dramatically among vertebrate species. It ranges from involution of epithelial sheets of cells through a circular blastopore in amphibians to ingression of ...
Manli Chuai, Guillermo Serrano Nájera, M. Serra, L. Mahadevan, Cornelis J. Weijer   +4 more
semanticscholar   +1 more source

Ptenb mediates gastrulation cell movements via Cdc42/AKT1 in zebrafish.

PLoS ONE, 2011
Phosphatidylinositol 3-kinase (PI3 kinase) mediates gastrulation cell migration in zebrafish via its regulation of PIP(2)/PIP(3) balance. Although PI3 kinase counter enzyme PTEN has also been reported to be essential for gastrulation, its role in ...
Chen-Min Yeh, Yi-Ching Liu, Ching-Jen Chang, Shih-Lei Lai, Chung-Der Hsiao, Shyh-Jye Lee   +5 more
doaj   +1 more source

Quo vadis PGRMC? Grand-Scale Biology in Human Health and Disease

Frontiers in Bioscience-Landmark, 2022
The title usage of Latin Quo vadis ‘where are you going’ extends the question Unde venisti from where ‘did you come?’ posed in the accompanying paper and extends consideration of how ancient eukaryotic and eumetazoan functions of progesterone receptor ...
Michael A. Cahill
doaj   +1 more source

Gastrulation in C. elegans [PDF]

WormBook, 2005
Gastrulation is the process by which the germ layers become positioned in an embryo. C. elegans gastrulation serves as a model for studying the molecular mechanisms of diverse cellular and developmental phenomena, including morphogenesis, cell polarization, cell-cell signaling, actomyosin contraction and cell-cell adhesion.
Jeremy Nance, Jen Yi Lee, Bob Goldstein
openaire   +2 more sources