Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation.
Jaeho Yoon +6 more
doaj +1 more source
Quantitative imaging of the collective cell movements shaping an embryo [PDF]
The recent development of imaging and image processing techniques, such as 4D microscopy and 3D cell tracking, enables analysis through quantification of the movement of large cell populations in vivo.
Fraser, Scott E. +3 more
core +1 more source
Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo [PDF]
Sphox11/13b is one of the two hox genes of Strongylocentrotus purpuratus expressed in the embryo. Its dynamic pattern of expression begins during gastrulation, when the transcripts are transiently located in a ring of cells at the edge of the ...
Arenas-Mena, César +2 more
core +1 more source
A Developmental Requirement for HIRA-Dependent H3.3 Deposition Revealed at Gastrulation in Xenopus
Discovering how histone variants that mark distinct chromatin regions affect a developmental program is a major challenge in the epigenetics field. To assess the importance of the H3.3 histone variant and its dedicated histone chaperone HIRA, we used an ...
Emmanuelle Szenker +2 more
doaj +1 more source
Morphogenesis along the animal-vegetal axis: fates of primary quartet micromere daughters in the gastropod Crepidula fornicata. [PDF]
BackgroundThe Spiralia are a large, morphologically diverse group of protostomes (e.g. molluscs, annelids, nemerteans) that share a homologous mode of early development called spiral cleavage.
Henry, Jonathan Q +2 more
core +1 more source
Folded gastrulation and T48 drive the evolution of coordinated mesoderm internalization in flies
Gastrulation constitutes a fundamental yet diverse morphogenetic process of metazoan development. Modes of gastrulation range from stochastic translocation of individual cells to coordinated infolding of an epithelial sheet.
Silvia Urbansky +3 more
doaj +1 more source
Adhesive Crosstalk in Gastrulation [PDF]
Recent studies show that signaling through integrin receptors is required for normal cell movements during Xenopus gastrulation. Integrins function in this process by modulating the activity of cadherin adhesion molecules within tissues undergoing convergence and extension movements.
Montero, J., Heisenberg, C.
openaire +3 more sources
Retinoic Acid is Required for Normal Morphogenetic Movements During Gastrulation
Retinoic acid (RA) is a central regulatory signal that controls numerous developmental processes in vertebrate embryos. Although activation of Hox expression is considered one of the earliest functions of RA signaling in the embryo, there is evidence ...
Michal Gur +3 more
doaj +1 more source
Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42 [PDF]
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood.
I-Chen Hung +5 more
doaj +1 more source
FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation [PDF]
Fibroblast growth factor (FGF) signaling controls a vast array of biological processes including cell differentiation and migration, wound healing and malignancy.
Kadam, Snehalata +3 more
core +4 more sources

