Results 31 to 40 of about 10,115 (192)
eLife, 2022 The morphogenic process of convergent thickening (CT) was originally described as the mediolateral convergence and radial thickening of the explanted ventral involuting marginal zone (IMZ) of Xenopus gastrulae (Keller and Danilchik, 1988).
David R Shook +9 more
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Epigenetic regulator function through mouse gastrulation
Nature, 2020 During ontogeny, proliferating cells become restricted in their fate through the combined action of cell-type-specific transcription factors and ubiquitous epigenetic machinery, which recognizes universally available histone residues or nucleotides in a ...
Stefanie Grosswendt +9 more
semanticscholar +1 more source
Epiblast morphogenesis before gastrulation.
Developmental Biology, 2015 The epiblast is a single cell-layered epithelium which generates through gastrulation all tissues in an amniote embryo proper. Specification of the epiblast as a cell lineage in early development is coupled with that of the trophoblast and hypoblast, two lineages dedicated to forming extramebryonic tissues.
Guojun Sheng
semanticscholar +4 more sources
eLife, 2018 In vivo, the primary molecular mechanotransductive events mechanically initiating cell differentiation remain unknown. Here we find the molecular stretching of the highly conserved Y654-β-catenin-D665-E-cadherin binding site as mechanically induced by ...
Jens-Christian Röper +8 more
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The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish
Biology, 2021 Cell adhesion and polarized cellular behaviors play critical roles in a wide variety of morphogenetic events. In the zebrafish embryo, epiboly represents an important process of epithelial morphogenesis that involves differential cell adhesion and ...
Ji-Tong Li +4 more
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Cell Reports, 2017 Apela (also known as Elabela, Ende, and Toddler) is a small signaling peptide that activates the G-protein-coupled receptor Aplnr to stimulate cell migration during zebrafish gastrulation.
Laina Freyer +10 more
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eLife, 2021 Metastasis is responsible for approximately 90% of cancer-associated mortality but few models exist that allow for rapid and effective screening of anti-metastasis drugs.
Joji Nakayama +6 more
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Candidate Heterotaxy Gene FGFR4 Is Essential for Patterning of the Left-Right Organizer in Xenopus
Frontiers in Physiology, 2018 Congenital heart disease (CHD) is the most common birth defect, yet its genetic causes continue to be obscure. Fibroblast growth factor receptor 4 (FGFR4) recently emerged in a large patient exome sequencing study as a candidate disease gene for CHD and ...
Emily Sempou +3 more
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Frontiers in Cell and Developmental Biology, 2019 The vertebrate anterior-posterior (A-P = craniocaudal) axis is evidently made by a timing mechanism. Evidence has accumulated that tentatively identifies the A-P timer as being or involving Hox temporal collinearity (TC). Here, I focus on the two current
Antony J. Durston
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Cells, 2021 Gastrulation is a critical step in the establishment of a basic body plan during development. Convergence and extension (CE) cell movements organize germ layers during gastrulation.
Jaeho Yoon +6 more
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