Results 41 to 50 of about 81,543 (257)
Furry is required for cell movements during gastrulation and functionally interacts with NDR1
Scientific Reports, 2021 Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes are established. Cell polarization is essential during gastrulation, driving asymmetric cell division, cell movements, and cell ...
Ailen S. Cervino +5 more
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The early stages of heart development: insights from chicken embryos [PDF]
, 2016 The heart is the first functioning organ in the developing embryo and the detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the ...
Alsan +19 more
core +2 more sources
Hox genes control vertebrate body elongation by collinear Wnt repression
eLife, 2015 In vertebrates, the total number of vertebrae is precisely defined. Vertebrae derive from embryonic somites that are continuously produced posteriorly from the presomitic mesoderm (PSM) during body formation.
Nicolas Denans +2 more
doaj +1 more source
The distribution of Dishevelled in convergently extending mesoderm [PDF]
, 2013 Convergent extension (CE) is a conserved morphogenetic movement that drives axial lengthening of the primary body axis and depends on the planar cell polarity (PCP) pathway.
Bretschneider, Till +3 more
core +1 more source
Gastrulation in C. elegans [PDF]
WormBook, 2005 Gastrulation is the process by which the germ layers become positioned in an embryo. C. elegans gastrulation serves as a model for studying the molecular mechanisms of diverse cellular and developmental phenomena, including morphogenesis, cell polarization, cell-cell signaling, actomyosin contraction and cell-cell adhesion.
Jeremy, Nance +2 more
openaire +2 more sources
Ingression-type cell migration drives vegetal endoderm internalisation in the Xenopus gastrula
eLife, 2017 During amphibian gastrulation, presumptive endoderm is internalised as part of vegetal rotation, a large-scale movement that encompasses the whole vegetal half of the embryo. It has been considered a gastrulation process unique to amphibians, but we show
Jason WH Wen, Rudolf Winklbauer
doaj +1 more source
Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity [PDF]
, 2010 Migration is a complex, dynamic process that has largely been studied using qualitative or static approaches. As technology has improved, we can now take quantitative approaches towards understanding cell migration using in vivo imaging and tracking ...
Aracena +54 more
core +4 more sources
Cells under Tension Drive Gastrulation [PDF]
Developmental Cell, 2020 In this issue of Developmental Cell, Muncie et al. describe the generation of gastrulation-like foci of cells within micropatterned colonies of pluripotent stem cells. This demonstration of mechanosensitive β-catenin/Wnt-dependent specification of cell fate during gastrulation illustrates the insights gleaned by placing stem cells in embryo-like ...
Clayton, Schwarz +1 more
openaire +2 more sources
Substrate stiffness affects early differentiation events in embryonic stem cells [PDF]
European Cells & Materials, 2009 Embryonic stem cells (ESC) are both a potential source of cells for tissue replacement therapies and an accessible tool to model early embryonic development.
ND Evans +8 more
doaj
Nature Communications, 2023 Understanding of the molecular drivers of lineage diversification and tissue patterning during primary germ layer development requires in-depth knowledge of the dynamic molecular trajectories of cell lineages across a series of developmental stages of ...
Ran Wang +13 more
doaj +1 more source