Results 31 to 40 of about 2,723,058 (227)

GATA3 (GATA binding protein 3) [PDF]

, 2012
Review on GATA3 (GATA binding protein 3), with data on DNA, on the protein encoded, and where the gene is ...
Bouchard, M, Tremblay, M
core   +1 more source

Hypoparathyroidism, sensorineural deafness, and renal dysgenesis syndrome with a mutation [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2015
Hypoparathyroidism, sensorineural deafness, and renal dysgenesis syndrome is an autosomal dominant disease caused by mutations in the GATA3 gene on chromosome 10p15.
Yong Suk Shim, Woohyeok Choi, Il Tae Hwang, Seung Yang   +3 more
doaj   +1 more source

GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer [PDF]

Cell Death & Disease, 2019
Abstract GATA3 has emerged as a prominent transcription factor required for maintaining mammary-gland homeostasis. GATA3 loss is associated with aggressive breast cancer development, but the mechanism by which breast cancer is affected by the loss of GATA3 function remains unclear.
Yu, Wenqian, Huang, Wei, Yang, Yang, Qiu, Rongfang, Zeng, Yi, Hou, Yongqiang, Sun, Gancheng, Shi, Hang, Leng, Shuai, Feng, Dandan, Chen, Yang, Wang, Shuang, Teng, Xu, Yu, Hefen, Wang, Yan   +14 more
openaire   +2 more sources

Bcl11b, a novel GATA3-interacting protein, suppresses Th1 while limiting Th2 cell differentiation [PDF]

, 2018
GATA-binding protein 3 (GATA3) acts as the master transcription factor for type 2 T helper (Th2) cell differentiation and function. However, it is still elusive how GATA3 function is precisely regulated in Th2 cells.
Bing Sun, Gangqing Hu, Chao Zhong, Ming Zhao, Liu, P, Fang, D, Ryoji Yagi, Zhu, J, Kairong Cui, Keji Zhao, Cui, K, Oler, AJ, Suveena Sharma, Pentao Liu, Rama Krishna Gurram, Sun, B, Zhao, K, Hu, G, Gurram, RK, Zhong, C, Jinfang Zhu, Andrew J. Oler, Zhao, M, Yagi, R, Difeng Fang, Sharma, S   +25 more
core   +1 more source

Mechanism of RNA-Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis. [PDF]

Kaohsiung J Med Sci
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Liu MY, Yao HB, Chen C.
europepmc   +2 more sources

Silencing of GATA3 defines a novel stem cell-like subgroup of ETP-ALL

Journal of Hematology & Oncology, 2016
Background GATA3 is pivotal for the development of T lymphocytes. While its effects in later stages of T cell differentiation are well recognized, the role of GATA3 in the generation of early T cell precursors (ETP) has only recently been explored.
L. Fransecky, M. Neumann, S. Heesch, C. Schlee, J. Ortiz-Tanchez, S. Heller, M. Mossner, S. Schwartz, L. H. Mochmann, K. Isaakidis, L. Bastian, U. R. Kees, T. Herold, K. Spiekermann, N. Gökbuget, C. D. Baldus   +15 more
doaj   +1 more source

Table_1_Divergent lncRNA GATA3-AS1 Regulates GATA3 Transcription in T-Helper 2 Cells.DOCX

, 2018
Long non-coding RNAs (lncRNAs) possess a diverse array of regulatory functions including activation and silencing of gene transcription, regulation of splicing, and coordinating epigenetic modifications.
Nathaniel Chapman (5903219), Laura C. Kim (5903216), Thomas M. Aune (237367), Charles F. Spurlock (5903222), Guzel Shaginurova (5903213), Hunter R. Gibbons (5903210)   +5 more
core   +1 more source

Table3_A GATA3 gene mutation that causes incorrect splicing and HDR syndrome: a case study and literature review.doc

, 2023
Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is an infrequent autosomal dominant genetic disorder caused by haploinsufficiency of the GATA binding protein 3 (GATA3) gene.
Yilun Tao (11429791), Wenxia Song (480265), Wenxia Song, Xiaoze Li (456068), Haiwei Wang, Dong Han, Lihong Wang (14991), Chen Zhao, Lin Yang (45852), Lihong Wang, Dong Han (199240), Lin Yang, Haiwei Wang (6864011), Yilun Tao, Chen Zhao (225070), Xiaoze Li   +15 more
core   +1 more source

Identification of GATA3 as a Breast Cancer Prognostic Marker by Global Gene Expression Meta-analysis [PDF]

Cancer Research, 2005
Abstract GATA binding protein 3 (GATA3) is a transcriptional activator highly expressed by the luminal epithelial cells in the breast. Here we did a meta-analysis of the available breast cancer cDNA data sets on a cohort of 305 patients and found that GATA3 was one of the top genes with low expression in invasive carcinomas with poor ...
Rohit, Mehra, Sooryanarayana, Varambally, Lei, Ding, Ronglai, Shen, Michael S, Sabel, Debashis, Ghosh, Arul M, Chinnaiyan, Celina G, Kleer   +7 more
openaire   +2 more sources

Table2_A GATA3 gene mutation that causes incorrect splicing and HDR syndrome: a case study and literature review.xlsx

, 2023
Hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome is an infrequent autosomal dominant genetic disorder caused by haploinsufficiency of the GATA binding protein 3 (GATA3) gene.
Yilun Tao (11429791), Wenxia Song (480265), Lin Yang (45852), Dong Han (199240), Xiaoze Li (456068), Haiwei Wang (6864011), Lihong Wang (14991), Chen Zhao (225070)   +7 more
core   +1 more source