Results 91 to 100 of about 6,913 (153)

CD147 promotes NSCLC metastasis by inducing secretory autophagy-dependent exosome secretion via TRIM56-mediated ubiquitination and degradation of GCN2. [PDF]

Cell Death Differ
Yang J, Liao C, Liang X, Ke Y, Sun Y, Huang M, Qian M, Yang X, Cui H, Bian H, Chen Z, Kong L.   +11 more
europepmc   +1 more source

Nexus of IDO1/Kynurenine Pathway to T-Cell Exhaustion: Hypoxia-Induced Tryptophan Metabolism in Glioblastoma. [PDF]

Metabolites
Abikenari M, Nageeb G, Ha JH, Sjoholm MA, Liu J, Bergsneider B, Valenzuela J, Poe J, Bog Cho K, Verma R, Wu C, Sanker V, Medikonda R, Kim LH, Choi J, Banu MA, Lim M.   +16 more
europepmc   +1 more source

Tuning tRNA synthetase inhibition reveals parabolic induction of stress granules limited in size and RNA content. [PDF]

RNA
Baymiller M, Helton NS, Dodd B, Moon SL.
europepmc   +1 more source

The integrated stress response in cancer: mechanisms of tumor adaptation and therapeutic targeting. [PDF]

Biochem Soc Trans
Maldonado E, McIsaac E, Ursini-Siegel J.
europepmc   +1 more source

Integrated Stress Response (ISR) Modulators in Vascular Diseases. [PDF]

Cells
Kalinin A, Zubkova E, Beloglazova I, Parfyonova Y, Menshikov M.   +4 more
europepmc   +1 more source

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review). [PDF]

Int J Mol Med
Zhang C, Han Y, Yao W, Hong Q, Chen N.
europepmc   +1 more source

Activation of the integrated stress response contributes to developmental delay and seizures caused by mitochondrial prolyl-tRNA synthetase (PARS2) deficiency. [PDF]

Redox Biol
Xu M, Liu Y, Ma R, Fan W, Duan J, Deng H, Ma Y, Ge W.   +7 more
europepmc   +1 more source

WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response. [PDF]

Nat Commun
Tjeerdsma RB, Ng TF, Roorda M, Bianchi D, Yang S, Bonnet C, VanInsberghe M, Everts M, Bakker FJ, de Boer HR, Moatti N, Hustedt N, Yin JZ, Hoeg L, Leibovitch M, Sicheri F, van Oudenaarden A, de Jong S, van den Berg J, Tanenbaum ME, Brummelkamp TR, Durocher D, van Vugt MATM.   +22 more
europepmc   +1 more source

Amino Acids as Targets for Immunotherapy against Solid Tumors. [PDF]

Cell Biochem Biophys
da Costa KVV, Passos GA, Botelho RJS, Ruza MSV, Dias-Lopes G, Silva RCMC.   +5 more
europepmc   +1 more source

Immunometabolic control of cytokine production by micronutrients in health, aging, and inflammation. [PDF]

Front Immunol
Ghosh J, Chattopadhyay D.
europepmc   +1 more source