Results 101 to 110 of about 7,295 (170)

An inhibitor of GCN2 and the integrated stress response directly targets ZAK protein kinase to limit cytotoxicity. [PDF]

J Biol Chem
Misra J, Spandau DF, Vilseck JZ, Anthony TG, Staschke KA, Wek RC.   +5 more
europepmc   +1 more source

Extracellular vesicles derived by hypoxic preconditioned EPCs attenuated atherosclerosis by suppressing ferroptosis via regulating arginine metabolism. [PDF]

Redox Biol
Luo X, Zhu X, Chen Y, Guo Y, Xu B, Mou J, Wang M, Gu Q, Sun Q, Lv Y, Huang X, Zeng M, Yi B, Liu X, Bai X, Fang C, Li J, Yu B, Jia H.   +18 more
europepmc   +1 more source

Amino acid insufficiency orchestrates AMPK and mTOR signaling. [PDF]

Fundam Res
Li T, Zhao L, Jia D.
europepmc   +1 more source

The hallmarks of protein and amino acid restriction in aging and longevity. [PDF]

Cell Press Blue
Knopf BA, Lamming DW.
europepmc   +1 more source

GCN2 in proteostasis: structural logic, signalling networks and disease. [PDF]

FEBS J
Zhu J, Marciniak SJ.
europepmc   +1 more source

A Novel Potent and Selective GCN2 Inhibitor, APL-4098, Has Antileukemic Activity through Dysregulation of Mitochondrial Function. [PDF]

Clin Cancer Res
Román-Trufero M, Whitlock G, Seydoux C, Blighe K, Perfler B, Zebisch A, Butt R, Fuchter MJ, Auner HW, Clemo N.   +9 more
europepmc   +1 more source

Codon Optimality Modulates Cellular Stress and Innate Immune Responses Triggered by Exogenous RNAs. [PDF]

J Mol Biol
Seephetdee C, Bejar N, Castillo KD, Chau E, Nguyen TY, Godin B, Kiss DL.   +6 more
europepmc   +1 more source

Glycine promotes cardiomyocyte proliferation and heart regeneration via the GCN2/AKT signaling axis. [PDF]

Theranostics
Wang F, Zhang X, Tang Y, He Y, Wang W, Zeng A, Liang L, Wang J, Zeng C.   +8 more
europepmc   +1 more source

Regulatory dynamics of monosomes and polysomes in cellular adaptation. [PDF]

J Biochem
Imai H, Yamashita A.
europepmc   +1 more source

The kynurenine pathway in RNA virus infection: immunometabolic control of antiviral defense and viral persistence. [PDF]

Front Immunol
Calderón-Sandate DN, Huerta-Garza MJ, Márquez-Reyna BA, Cañedo-Figueroa DM, Hernández-Rodríguez X, Lira-Hernández FI, Osuna-Ramos JF, Cardoso-Ortiz J, Del Ángel RM, Santos-Mena AO, De Jesús-González LA.   +10 more
europepmc   +1 more source