Results 121 to 130 of about 7,295 (170)

Overcoming immunotherapy resistance in breast cancer: a novel strategy by targeting the integrated stress response. [PDF]

Front Cell Dev Biol
Yue J, Pu T, He D, Luo Y, Ruan S, Li H, Zhan J, Su G, Su J, Chen S, Huang G.   +10 more
europepmc   +1 more source

Batch- and Composition-Controlled Reanalysis of Bulk and Single-Nucleus Transcriptomes Reveals Co-Enrichment of Glial Complement and of Translational Signatures in Parkinson's Disease and Amyotrophic Lateral Sclerosis. [PDF]

Int J Mol Sci
Jung C.
europepmc   +1 more source

Roles of the integrated stress response in regulation of inflammatory reactions. [PDF]

Front Immunol
Jiang F, Liu GS, Liu J, Cui X, Xing Y.
europepmc   +1 more source

Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma. [PDF]

Cell Death Discov
Racineau E, Lallier M, Postec A, Amiaud J, Thépault RA, Brion R, Battaglia S, Charrier C, Colle MA, Brounais-Le Royer B, Baud'huin M, Verrecchia F, Ory B, Georges S, Lamoureux F.   +14 more
europepmc   +1 more source

Saccharomyces cerevisiae as a model for mammalian diseases. [PDF]

FEMS Yeast Res
Sattlegger E, Schiemann AH.
europepmc   +1 more source

The Tryptophan Paradox: From Microbiome-Mediated Homeostasis to Tumor-Driven Immune Escape. [PDF]

Int J Mol Sci
Cho A, Wu C, Theodoropoulos G, Nagarajan M, Murphy AM, Heller KF, Savaraj N, Lampidis TJ, Wangpaichitr M.   +8 more
europepmc   +1 more source

The competition of amino acid among tumors, tumor-associated macrophages and T cells based on metabolic reprogramming. [PDF]

iScience
Xianyu C, Song Y, Zhao C, Min Q, Wang Z, Zhang M, Zhang B.   +6 more
europepmc   +1 more source

Gut microbial signatures in poultry under low-protein diets and lysine restriction: implications for precision nutrition. [PDF]

Vet Anim Sci
Salahi A, El-Ghany WAA.
europepmc   +1 more source

Activation of GCN2 by the ribosomal P-stalk [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance General control nonderepressible 2 (GCN2) phosphorylates eIF2α, regulating translation in response to nutritional stress. Here, we show that although tRNA stimulates purified, recombinant human GCN2 in vitro, mammalian ribosomes are even more potent GCN2 activators.
Roger L. Williams, Ramanujan Shankar Hegde, Stephen H. McLaughlin   +2 more
exaly   +4 more sources