Results 121 to 130 of about 8,559 (195)

ATF4 orchestrates cancer hallmarks: Stress adaptation, metabolic reprogramming and immune suppression. [PDF]

iScience
Peng Z, Xu T, Xia Z, Han H, Ding B, Yang L, Ren W, Ye H.   +7 more
europepmc   +1 more source

Translational resistance to amino acid starvation in breast cancer cells revealed by ribosome profiling. [PDF]

iScience
Li F, Zhang S, Duan H, Wolf DA, Yang X.
europepmc   +1 more source

Glycine promotes cardiomyocyte proliferation and heart regeneration via the GCN2/AKT signaling axis. [PDF]

Theranostics
Wang F, Zhang X, Tang Y, He Y, Wang W, Zeng A, Liang L, Wang J, Zeng C.   +8 more
europepmc   +1 more source

Suppression rather than activation of the integrated stress response (GCN2-ATF4) pathway extends lifespan in the fly. [PDF]

Proc Natl Acad Sci U S A
Götz MS, Hayman DJ, Adams G, Obata F, Simons MJP.   +4 more
europepmc   +1 more source

Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2 [PDF]

ACS Medicinal Chemistry Letters, 2014
Jean-Francois, Brazeau, Gerard, Rosse
openaire   +2 more sources

Therapeutic rescue of pathogenic asparaginyl-tRNA synthetase alleles. [PDF]

Mol Ther Nucleic Acids
Samuels TN, Kakadia JH, Ward C, Abdullatif F, Mendes MI, Smith DE, Heilmann R, Wu F, Swiercz JM, Salamons GS, Hoffman K, Gebregiworgis T, O'Donoghue P, Heinemann IU.   +13 more
europepmc   +1 more source

Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis. [PDF]

Elife
Jonker PB, Sadullozoda M, Cognet G, Apiz Saab JJ, Sokol KH, Wu VX, Kumari D, Sheehan C, Ozgurses ME, Agovino D, Croley G, Dzierozynski LN, Cai C, Ziolkowski LM, Patel SA, Bock-Hughes A, Macleod KF, Shah H, Coloff JL, Lien EC, Muir A.   +20 more
europepmc   +1 more source

Structural Transformation of a BRAF Inhibitor into a Selective PKR Inhibitor. [PDF]

J Med Chem
Yin J, Srivastava S, Tang X, Galbraith C, Uchenunu O, Miller J, Liu Y, Crescenzi I, Kiyota T, Kurinov I, Costa-Mattioli M, Laufer R, Aman A, Rottapel R, Ramnauth J, Haakonsen DL, Uehling DE, Sicheri F.   +17 more
europepmc   +1 more source

Structural basis for pseudokinase-mediated regulation of GCN2 in the integrated stress response. [PDF]

Proc Natl Acad Sci U S A
Liu Y, Misra J, Bhowmik DR, O'Boyle B, Staschke KA, Kannan N, Wek RC, Jura N.   +7 more
europepmc   +1 more source

Cellular Responses to Flavivirus Infections: Stress Signaling at the Crossroads of Host Defense and Virus Infection. [PDF]

Viruses
Badu P, González ETC, Pager CT.
europepmc   +1 more source