Results 141 to 150 of about 8,559 (195)

CD147 promotes NSCLC metastasis by inducing secretory autophagy-dependent exosome secretion via TRIM56-mediated ubiquitination and degradation of GCN2. [PDF]

Cell Death Differ
Yang J, Liao C, Liang X, Ke Y, Sun Y, Huang M, Qian M, Yang X, Cui H, Bian H, Chen Z, Kong L.   +11 more
europepmc   +1 more source

Integrated Stress Response (ISR) Modulators in Vascular Diseases. [PDF]

Cells
Kalinin A, Zubkova E, Beloglazova I, Parfyonova Y, Menshikov M.   +4 more
europepmc   +1 more source

Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review). [PDF]

Int J Mol Med
Zhang C, Han Y, Yao W, Hong Q, Chen N.
europepmc   +1 more source

Activation of the integrated stress response contributes to developmental delay and seizures caused by mitochondrial prolyl-tRNA synthetase (PARS2) deficiency. [PDF]

Redox Biol
Xu M, Liu Y, Ma R, Fan W, Duan J, Deng H, Ma Y, Ge W.   +7 more
europepmc   +1 more source

Amino Acids as Targets for Immunotherapy against Solid Tumors. [PDF]

Cell Biochem Biophys
da Costa KVV, Passos GA, Botelho RJS, Ruza MSV, Dias-Lopes G, Silva RCMC.   +5 more
europepmc   +1 more source

Immunometabolic control of cytokine production by micronutrients in health, aging, and inflammation. [PDF]

Front Immunol
Ghosh J, Chattopadhyay D.
europepmc   +1 more source

WEE1 inhibitors trigger GCN2-mediated activation of the integrated stress response. [PDF]

Nat Commun
Tjeerdsma RB, Ng TF, Roorda M, Bianchi D, Yang S, Bonnet C, VanInsberghe M, Everts M, Bakker FJ, de Boer HR, Moatti N, Hustedt N, Yin JZ, Hoeg L, Leibovitch M, Sicheri F, van Oudenaarden A, de Jong S, van den Berg J, Tanenbaum ME, Brummelkamp TR, Durocher D, van Vugt MATM.   +22 more
europepmc   +1 more source

Structural insights into HRI kinase activity and inhibition. [PDF]

Biochem Soc Trans
Cao M, Masson GR.
europepmc   +1 more source

Metabolic and transcriptional plasticity supports CD8⁺ T cell resilience and anti-tumor immunity under nutrient stress. [PDF]

Immunity
Scaglione M, Knight M, Trihemasava K, Rome K, Archambault AS, Oh J, Tanaka E, Hall E, Van Le TN, Lines CL, Goldspiel B, Fazelinia H, Queriault C, Turner L, Parnaik T, Xu J, Brown M, Bardhan O, Axsom J, Bennett FC, Spruce LA, Bartman C, Mesaros C, Klein Geltink RI, Conn CS, Bailis W.   +25 more
europepmc   +1 more source

Multilayered regulation of TORC1 signaling by Ait1, Gcn2, and SEAC/GATOR during nitrogen limitation and starvation. [PDF]

Nat Commun
Padilla CM, Lim J, Lipinski AA, Langlais PR, Capaldi AP.   +4 more
europepmc   +1 more source