Results 81 to 90 of about 6,913 (153)

Glycine promotes cardiomyocyte proliferation and heart regeneration via the GCN2/AKT signaling axis. [PDF]

Theranostics
Wang F, Zhang X, Tang Y, He Y, Wang W, Zeng A, Liang L, Wang J, Zeng C.   +8 more
europepmc   +1 more source

Triazolo[4,5-d]pyrimidine Derivatives as Inhibitors of GCN2 [PDF]

ACS Medicinal Chemistry Letters, 2014
Jean-Francois, Brazeau, Gerard, Rosse
openaire   +2 more sources

The integrated stress response in apicomplexan and trypanosomatid parasites: balancing survival and pathogenesis. [PDF]

Front Immunol
Hammi I, Darif D, Arnoult D.
europepmc   +1 more source

Overcoming immunotherapy resistance in breast cancer: a novel strategy by targeting the integrated stress response. [PDF]

Front Cell Dev Biol
Yue J, Pu T, He D, Luo Y, Ruan S, Li H, Zhan J, Su G, Su J, Chen S, Huang G.   +10 more
europepmc   +1 more source

Roles of the integrated stress response in regulation of inflammatory reactions. [PDF]

Front Immunol
Jiang F, Liu GS, Liu J, Cui X, Xing Y.
europepmc   +1 more source

Activation of the Arabidopsis thaliana GCN2-eIF2α module by salicylic acid: Biochemical and phenotypic similarities between gcn2 mutant and wild type.

microPublication biology
Plants rely on arsenal of defenses to combat numerous stresses. Salicylic acid (SA) is a crucial hormone in plant defense, yet its role in translational regulation is underexplored. We investigated the SA signaling through the stress sentinel protein kinase, GCN2 and its substrate, eIF2α, in Arabidopsis thaliana .
Wynn, Morgan, Lokdarshi, Ansul, Diaz, Daniel Rincon   +2 more
openaire   +1 more source

Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma. [PDF]

Cell Death Discov
Racineau E, Lallier M, Postec A, Amiaud J, Thépault RA, Brion R, Battaglia S, Charrier C, Colle MA, Brounais-Le Royer B, Baud'huin M, Verrecchia F, Ory B, Georges S, Lamoureux F.   +14 more
europepmc   +1 more source

The Tryptophan Paradox: From Microbiome-Mediated Homeostasis to Tumor-Driven Immune Escape. [PDF]

Int J Mol Sci
Cho A, Wu C, Theodoropoulos G, Nagarajan M, Murphy AM, Heller KF, Savaraj N, Lampidis TJ, Wangpaichitr M.   +8 more
europepmc   +1 more source

The competition of amino acid among tumors, tumor-associated macrophages and T cells based on metabolic reprogramming. [PDF]

iScience
Xianyu C, Song Y, Zhao C, Min Q, Wang Z, Zhang M, Zhang B.   +6 more
europepmc   +1 more source

Saccharomyces cerevisiae as a model for mammalian diseases. [PDF]

FEMS Yeast Res
Sattlegger E, Schiemann AH.
europepmc   +1 more source