Results 61 to 70 of about 909 (176)

Image_1_Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.tif

, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yaping Wang (289641), Zuoyan Zhu (209396), Lanjie Liao (419568), Bin Gui (542725), Rong Huang (298496), Yangyang Li (554659), Cheng Yang (273624), Liangming Chen (3401597), Yongming Li (584924), Yangyu Li (13761172)   +9 more
core   +1 more source

Characterization of grass carp reovirus minor core protein VP4

Virology Journal, 2012
Background Grass Carp Reovirus (GCRV), a tentative member in the genus Aquareovirus of family Reoviridae, contains eleven segmented (double-stranded RNA) dsRNA genome which encodes 12 proteins.
Yan Liming, Guo Hong, Sun Xiaoyun, Shao Ling, Fang Qin   +4 more
doaj   +1 more source

An aquatic virus exploits the IL6-STAT3-HSP90 signaling axis to promote viral entry.

PLoS Pathogens, 2023
Viral seasonality in the aquaculture industry is an important scientific issue for decades. While the molecular mechanisms underpinning the temperature-dependent pathogenesis of aquatic viral diseases remain largely unknown.
Guoli Hou, Zhao Lv, Wenzhi Liu, Shuting Xiong, Qiushi Zhang, Chun Li, Xiaodong Wang, Liang Hu, Chunhua Ding, Rui Song, Hongquan Wang, Yong-An Zhang, Tiaoyi Xiao, Junhua Li   +13 more
doaj   +1 more source

Pro-inflammatory regulatory mechanism of C5a/C5aR pathway in GCRV-infected grass carp (Ctenopharyngodon idella)

Aquaculture Reports, 2023
Death of grass carp (Ctenopharyngodon idella) caused by grass carp reovirus (GCRV) infection severely restricts the development of the grass carp industry.
Baohong Xu, Hang Su, Changjun Chen, Qiaolin Liu, Tiaoyi Xiao, Yi Liu, Zhao Lv, Hongquan Wang, Zheyu Wen   +8 more
doaj   +1 more source

Table_1_Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.xlsx

, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yaping Wang (289641), Zuoyan Zhu (209396), Lanjie Liao (419568), Bin Gui (542725), Rong Huang (298496), Yangyang Li (554659), Cheng Yang (273624), Liangming Chen (3401597), Yongming Li (584924), Yangyu Li (13761172)   +9 more
core   +1 more source

Image_1_Integrative transcriptome analysis reveals alternative polyadenylation potentially contributes to GCRV early infection.pdf

, 2023
IntroductionGrass carp reovirus (GCRV), a member of the Aquareovirus genus in the Reoviridae family, is considered to be the most pathogenic aquareovirus. Productive viral infection requires extensive interactions between viruses and host cells. However,
Jingxuan Yan (17332465), Yonglin Peng (5557733), Jie Zhang (64655), Wenfei Du (9558029), Qin Fang (281352), Sheng Tan (431021)   +5 more
core   +1 more source

An Aquareovirus Exploits Membrane-Anchored HSP70 To Promote Viral Entry

Microbiology Spectrum, 2023
Temperature dependency of viral diseases in ectotherms has been an important scientific issue for decades, while the molecular mechanism behind this phenomenon remains largely mysterious. In this study, deploying infection with grass carp reovirus (GCRV),
Guoli Hou, Qiushi Zhang, Chun Li, Geye Ding, Lingling Hu, Xiaoying Chen, Zhao Lv, Yuding Fan, Jun Zou, Tiaoyi Xiao, Yong-An Zhang, Junhua Li   +11 more
doaj   +1 more source

Nonstructural protein NS17 of grass carp reovirus Honghu strain promotes virus infection by mediating cell-cell fusion and apoptosis

Virus Research, 2023
Fusion-associated small transmembrane (FAST) proteins can promote cell fusion, alter membrane permeability and trigger apoptosis to promote virus proliferation in orthoreoviruses.
Yanlin Dai, Yiqun Li, Xi Hu, Nan Jiang, Wenzhi Liu, Yan Meng, Yong Zhou, Chen Xu, Mingyang Xue, Yuding Fan   +9 more
doaj   +1 more source

Insights on the Multifunctional Activities of Magnolol

BioMed Research International, Volume 2019, Issue 1, 2019., 2019
Over years, various biological constituents are isolated from Traditional Chinese Medicine and confirmed to show multifunctional activities. Magnolol, a hydroxylated biphenyl natural compound isolated from Magnolia officinalis, has been extensively documented and shows a range of biological activities.
Jianhong Zhang, Zhixi Chen, Xianhua Huang, Weimei Shi, Rui Zhang, Meiling Chen, Hao Huang, Longhuo Wu, Antoni Camins   +8 more
wiley   +1 more source

Novel Duck Orthoreovirus Induces Ferroptosis in HD11 Cells by Hijacking Cellular Iron Metabolism and Promoting Iron Accumulation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Novel duck orthoreovirus (NDRV) infection induces severe splenic necrosis in ducks, resulting in a cascade of detrimental consequences, including immunosuppression, secondary infections, and diminished vaccine efficacy. Avian orthoreovirus (ARV) exhibits high tropism for macrophages, with splenic macrophages being identified as the primary target cells
Hongzhi Wang, Di Lei, Chenchen Jiang, Boyi Xu, Yi Tang, Rendong Fang, Zongfu Wu   +6 more
wiley   +1 more source