Results 51 to 60 of about 909 (176)

Characterization, Expression, and Ligand Binding of LGP2 and MDA5 in Largemouth Black Bass Micropterus salmoides (Lacepède, 1802)

open access: yesAquaculture Research, Volume 2023, Issue 1, 2023., 2023
Melanoma differentiation‐associated gene 5 (MDA5) and the laboratory of genetics and physiology 2 (LGP2) are family members of retinoic acid‐inducible gene I (RIG‐I)‐like receptors (RLRs), which play important roles in the immune response against pathogens invasion.
Xiangyu Pi   +6 more
wiley   +1 more source

Bid-deficient fish delay grass carp reovirus (GCRV) replication and attenuate GCRV-triggered apoptosis

open access: yesOncotarget, 2017
Bid, BH3-interacting domain death agonist, is a pro-apoptotic BH3-only member of Bcl-2 family, playing an important role in apoptosis. In the study, Bid genes from grass carp (Ctenopharyngodon idellus) and rare minnow (Gobiocypris rarus), named CiBid and GrBid, were cloned and analyzed.
He, Libo   +7 more
openaire   +2 more sources

IL6-STAT3-HSP90 axis regulates GCRV entry.

open access: yes, 2023
(A) GCO/CIK cells infected with GCRV (MOI = 5) at different temperatures for 1 h were prepared to quantify the relative genome entry by RT-PCR with the VP7 primer pair.
Rui Song (331963)   +13 more
core   +1 more source

IL6-STAT3 signaling pathway mediates temperature-dependent GCRV infection.

open access: yes, 2023
(A) Heat map analysis of DEGs that were up-regulated by GCRV infection in the GCRV-infected head kidney tissue was summarized (NCBI SRA database accession number PRJNA759556).
Rui Song (331963)   +13 more
core   +2 more sources

GCRV NS38 counteracts SVCV proliferation by intracellular antagonization during co-infection

open access: yesVirologica Sinica, 2023
Viral co-infection has been found in animals; however, the mechanisms of co-infection are unclear. The abundance and diversity of viruses in water make fish highly susceptible to co-infection. Here, we reported a co-infection in fish, which resulted in reduced host lethality and illustrated the intracellular molecular mechanism of viral co-infection ...
Zhuo-Cong Li   +10 more
openaire   +2 more sources

Inhibitor analysis revealed that clathrin-mediated endocytosis is involed in cellular entry of type III grass carp reovirus

open access: yesVirology Journal, 2018
Background Grass carp (Ctenopharyngodon idella) hemorrhagic disease is caused by an acute infection with grass carp reovirus (GCRV). The frequent outbreaks of this disease have suppressed development of the grass carp farming industry.
Hao Wang   +6 more
doaj   +1 more source

Table_2_Grass carp SERPINA1 inhibits GCRV infection through degrading CF2.xlsx

open access: yes, 2022
SERPINA1, a member of the serine protease inhibitor family, plays a role in viral infection and inflammation by regulating the activities of serine and cysteine proteases.
Yaping Wang (289641)   +9 more
core   +1 more source

Antibodies against outer-capsid proteins of grass carp reovirus expressed in E. coli are capable of neutralizing viral infectivity

open access: yesVirology Journal, 2011
Background Grass carp reovirus (GCRV), which causes severe infectious outbreaks of hemorrhagic disease in aquatic animals, is a highly pathogenic agent in the Aquareovirus genus of family Reoviridae.
Sun Xiaoyun, Shao Ling, Fang Qin
doaj   +1 more source

Fish type I and type II interferons: composition, receptor usage, production and function

open access: yesReviews in Aquaculture, Volume 12, Issue 2, Page 773-804, May 2020., 2020
Abstract Interferons (IFNs) have been reported in vertebrates from fish to mammals. To date, two types of IFNs, i.e. type I and type II IFNs have been reported in a range of fish species in aquaculture. In fish, type I IFNs are clarified into group I and group II, with two cysteines and four cysteines, and further into subgroups a, d, e, h, and b, c, f,
Zhen Gan   +4 more
wiley   +1 more source

Characterization of grass carp spleen transcriptome during GCRV infection

open access: yesGenetics and Molecular Research, 2016
The aim of the study was to investigate the grass carp hemorrhagic infection pathway and its key-related genes. Grass carp reovirus (GCRV) might cause hemorrhagic disease in grass carps. Healthy grass carp fingerlings (N = 60) were divided into control and infected groups.
B H, Xu   +8 more
openaire   +2 more sources

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